Contribution to the qualification of technical microwave systems and to the validation of microwave-assisted reactions and processes

Chemical Engineering and Technology

Volumn 28, Issue 8, 2005, Pages 871-881

  Nuchter M ^a   Ondruschka, Bernd ^a   Weiss D ^a   Beckert, R ^a   Bonrath, W ^b   Gum, A ^b  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b DSM NUTRITIONAL PRODUCTS LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL REACTORS; HEAT TRANSFER; IRRADIATION; MICROWAVES; PROCESS ENGINEERING; QUALITY CONTROL; TEMPERATURE MEASUREMENT; THERMAL EFFECTS;

IRRADIATION MODUS; MICROWAVE-ASSISTED PROCESSES; MICROWAVE-ASSISTED REACTIONS; MONITORING TECHNOLOGY; TECHNICAL MICROWAVE SYSTEMS;

CHEMICAL REACTIONS;

IRRADIATION;

EID: 23844498703     PISSN: 09307516     EISSN: None     Source Type: Journal    
DOI: 10.1002/ceat.200500136     Document Type: Article

References (35)

1. Act on Protection against Hazardous Substances (Chemicals Act), new version with notification from June 20, 2002, I 2090; finally changed through § 10 of the law from May 13, 2004, I 934.
2. Directive 2004/9/EG of the European Parliament and of the council for inspection and control of "Good Laboratory Praxis" (GLP) (codified version from Feb. 2, 2004).
3. Directive 2004/10/EG of the European Parliament and of the council for approximation of laws and administrative regulations for using "Good Laboratory Praxis" (GLP) for controlling the use in experiments with chemical compounds (codified version from Feb. 11, 2004).
4. M. Nüchter. B. Ondruschka, W. Bonrath, A. Gum, Green Chem. 2004, 6, 128.
5. M. Nüchter, B. Ondruschka, Nachr. Chem. 2003, 51, 522.
6. A. Loupy et al.. Synthesis 1998, 1213.
7. Y. Xu, Q.-X. Guo, Heterocycles 2004, 63, 903.
8. M. Panunzio et al., Mat. Res. Innovat. 2004, 8, 27.
9. S. K. Das, Synlett 2004, 915.
10. A. Dandia, K. Arya, M. Sati, S. Gautam, Tetrahedron 2004, 60, 5253.
11. N. C. Ganguly, M. Datta, Synlett 2004, 659.
12. M. O. Liu et al., J. Organomet. Chem. 2004, 689, 1078.
13. Technical microwave systems for application in organic synthesis are available from the following companies: MLS GmbH/Milestone srl. DE/IT www.mls-mikrowellen.de CEM USA www.cem.com Biotage/Personal Chemistry S www.biotage.com Anton Paar GmbH AT www.anton-paar.com Plasmatronika PI www.plazmatronika.pl Furthermore, there exist some modifications of domestic microwave ovens, which are used occasionally in organic synthesis. Also, reactions in systems of Prolabo (F) are described, but these systems are no longer available on the market.
14. R. S. Varma, Green Chem. 1999, 1, 43.
15. N. Kuhnert, Angew. Chem. Int. Ed. 2002, 41, 1863.
16. B. H. Hayes, Microwave Synthesis, CEM Publishing, Matthews, NC, 2002, 181.
17. H. G. O. Becker et al., Organikum, 20th ed., Wiley-VCH, Weinheim, New York 1999, 444.
18. A. Hantzsch, Liebigs Ann. Chem. 1882, 215, 1.
19. C. O. Kappe, Tetrahedron 1993, 32, 6937.
20. C. O. Kappe, D. Kumar, R. S. Varma, Synthesis 1999, 1799.
21. N. E. Leadbeater, M. Marco, Org. Lett. 2002, 4, 2973.
22. N. E. Leadbeater, M. Marco, J. Org. Chem. 2003, 68, 888.
23. N. E. Leadbeater, M. Marco, Angew. Chem. 2003, 115, 1445.
24. H. G. O. Becker et al., Organikum, 20th ed., Wiley-VCH, Weinheim, New York 1999, 503.
25. D. Bogdal, J. Chem. Res. 1998, 468.
26. G. V. Reddy et al., Synth. Comm. 2001, 31, 2881.
27. www.oc-praktikum.de. This site presents an internet project of eight German university research groups for a higher level of education of chemistry students in organic chemistry with modern aspects and detailed description of several experiments, also with alternative energy entry, facts of toxicology and eco-toxicology.
28. J. D. Ferguson, Mol. Diversity 2003, 7, 281.
29. J. J. Chen, S. V. Deshpande, Tetrahedron Lett. 2003, 44, 8873.
30. B. Hayes, Aldrichimica Acta 2004, 37, 66.
31. M. Nüchter, B. Ondruschka, W. Lautenschläger, DE 101 04 329 A1, A62C 3/16, 2001.
32. M. Nüchter et al., Chem. Eng. Technol. 2003, 26 (12), 1207. 10.1002/ceat.200301836
33. European Standard SN 60706, 1995, Method for Measuring Serviceability of Microwave Devices for Domestic Use and Similar Purposes.
34. S. K. Bansal et al., AAPS PharmSciTech 2004, 5, Art. 22 (www.aapspharmscitech.org) and literature cited there.
35. B. Pohl, Accred. Qual. Assur. 2004, 9, 503.