Pharmacokinetic/pharmacodynamic modelling of GnRH antagonist degarelix: A comparison of the non-linear mixed-effects programs NONMEM and NLME

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 31, Issue 6, 2004, Pages 441-461

  Tornøe, Christoffer W ^a   Agersø, Henrik ^a   Nielsen, Henrik A ^b   Madsen, Henrik ^b   Jonsson, E Niclas ^c  

^a Ferring Pharmaceuticals AS   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Degarelix; GnRH antagonist; NLME; Non linear mixed effects programs; NONMEM; Population pharmacokinetic pharmacodynamic modelling

Indexed keywords

DEGARELIX; FE 200486; GONADORELIN ANTAGONIST; UNCLASSIFIED DRUG;

ACCURACY; ALGORITHM; ARTICLE; CLINICAL TRIAL; COMPARTMENT MODEL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HUMAN; INTERMETHOD COMPARISON; MALE; METHODOLOGY; NONLINEAR SYSTEM; NORMAL HUMAN; OPEN STUDY; PARAMETRIC TEST; PHARMACOLOGICAL PARAMETERS; POPULATION; PRIORITY JOURNAL; PROSTATE CANCER; THEORETICAL MODEL;

ALGORITHMS; COMPUTER SIMULATION; GONADOTROPIN-RELEASING HORMONE; HUMANS; MODELS, BIOLOGICAL; OLIGOPEPTIDES;

EID: 23844460832     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-005-5911-1     Document Type: Article

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