Comparison of population pharmacokinetic modeling methods using simulated data: Results from the Population Modeling Workgroup

Statistics in Medicine

Volumn 16, Issue 11, 1997, Pages 1241-1262

  Roe, Denise J ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DRUG DISPOSITION; INTERMETHOD COMPARISON; PHARMACOKINETICS; POPULATION MODEL; STATISTICAL MODEL;

ANTI-ARRHYTHMIA AGENTS; DATA COLLECTION; HUMANS; INTESTINAL ABSORPTION; MALE; MODELS, CHEMICAL; PHARMACOKINETICS; QUINIDINE; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; RESEARCH DESIGN; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 0030970645     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0258(19970615)16:11<1241::AID-SIM527>3.0.CO;2-C     Document Type: Article

References (2)

1. Lindstrom, M. J. and Bates, D. M. 'Nonlinear mixed effects models for repeated measures data', Biometrics, 46, 673-687 (1990).
2. Wolfinger, R. D. 'Laplace's approximation for nonlinear mixed models', Biometrika, 80, 791-795 (1993).