Eukaryotic translational coupling in UAAUG stop-start codons for the bicistronic RNA translation of the non-long terminal repeat retrotransposon SART1

Molecular and Cellular Biology

Volumn 25, Issue 17, 2005, Pages 7675-7686

  Kojima, Kenji K ^a,b   Matsumoto, Takumi ^a   Fujiwara, Haruhiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; HYBRID PROTEIN; MESSENGER RNA; ORF1 PROTEIN; ORF2 PROTEIN; POL PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CONTROLLED STUDY; EUKARYOTE; LONG TERMINAL REPEAT; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROKARYOTE; RETROPOSON; RETROVIRUS; RIBOSOMAL FRAMESHIFTING; RNA STRUCTURE; RNA TRANSLATION; SILKWORM; SITE DIRECTED MUTAGENESIS; START CODON; STOP CODON; TRANSLATION INITIATION; VIRUS; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANTIGENS, NEOPLASM; BASE SEQUENCE; CODON, INITIATOR; CODON, TERMINATOR; FRAMESHIFTING, RIBOSOMAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OPEN READING FRAMES; PROTEIN BIOSYNTHESIS; RETROELEMENTS; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA, FUNGAL; SACCHAROMYCES CEREVISIAE;

BOMBYX MORI; CELLULAR ORGANISMS; EUKARYOTA; PROKARYOTA;

EID: 23844439948     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.17.7675-7686.2005     Document Type: Article

References (38)

1. Adhin, M. R., and J. van Duin. 1990. Scanning model for translational reinitiation in eubacteria. J. Mol. Biol. 213:811-818.
2. Ahmadian, G., J. S. Randhawa, and A. J. Easton. 2000. Expression of the ORF-2 protein of the human respiratory syncytial virus M2 gene is initiated by a ribosomal termination-dependent reinitiation mechanism. EMBO J. 19:2681-2689.
3. Aksoy, S., C. L. Squires, and C. Squires. 1984. Translational coupling of the trpB and trpA genes in the Escherichia coli tryptophan operon. J. Bacteriol. 157:363-367.
4. Belcourt, M. F., and P. J. Farabaugh. 1990. Ribosomal frameshifting in the yeast retrotransposon Ty: tRNAs induce slippage on a 7 nucleotide minimal site. Cell 62:339-352.
5. Bouhidel, K., C. Terzian, and H. Pinon. 1994. The full-length transcript of the I factor, a LINE element of Drosophila melanogaster, is a potential bicistronic RNA messenger. Nucleic Acids Res. 22:2370-2374.
6. Brodskii, L. I., V. V. Ivanov, I. L. Kalaidzidis, A. M. Leontovich, V. K. Nikolaev, S. I. Feranehuk, and V. A. Drachev. 1995. GeneBee-NET: an Internet-based server for analyzing biopolymers structure. Biokhimiia 60: 1221-1230. (In Russian.)
7. Ergün, S., C. Buschmann, J. Heukeshoven, K. Dammann, F. Schnieders, H. Lauke, F. Chalajour, N. Kilic, W. H. Strätling, and G. G. Schumann. 2004. Cell type-specific expression of LINE-1 open reading frames 1 and 2 in fetal and adult human tissues. J. Biol. Chem. 279:27753-27763.
8. Fütterer, J., Z. Kiss-László, and T. Hohn. 1993. Nonlinear ribosome migration on cauliflower mosaic virus 35S RNA. Cell 73:789-802.
9. Han, J. S., S. T. Szak, and J. D. Boeke. 2004. Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes. Nature 429:268-274.
10. Hinnebusch, A. G. 1997. Translational regulation of yeast GCN4. A window on factors that control initiator-tRNA binding to the ribosome. J. Biol. Chem. 272:21661-21664.
11. Horvath, C. M., M. A. Williams, and R. A. Lamb. 1990. Eukaryotic coupled translation of tandem cistrons: identification of the influenza B virus BM2 polypeptide. EMBO J. 9:2639-2647.
12. Ilves, H., O. Kahre, and M. Speek. 1992. Translation of the rat LINE bicistronic RNAs in vitro involves ribosomal reinitiation instead of frameshifting. Mol. Cell. Biol. 12:4242-4248.
13. Inokuchi, Y., A. Hirashima, Y. Sekine, L. Janosi, and A. Kaji. 2000. Role of ribosome recycling factor (RRF) in translational coupling. EMBO J. 19: 3788-3798.
14. Jacks, T., M. D. Power, F. R. Masiarz, P. A. Luciw, P. J. Barr, and H. E. Varmus. 1988. Characterization of ribosomal frameshifting in HIV-1 gag-pol expression. Nature 331:280-283.
15. Kawakami, K., S. Pande, B. Faiola, D. P. Moore, J. D. Boeke, P. J. Farabaugh, J. N. Strathern, Y. Nakamura, and D. J. Garfinkel. 1993. A rare tRNA-Arg(CCU) that regulates Ty1 element ribosomal frameshifting is essential for Ty1 retrotransposition in Saccharomyces cerevisiae. Genetics 135: 309-320.
16. Kim, Y. G., S. Maas, and A. Rich. 2001. Comparative mutational analysis of cis-acting RNA signals for translational frameshifting in HIV-1 and HTLV-2. Nucleic Acids Res. 29:1125-1131.
17. Kojima, K. K., and H. Fujiwara. 2003. Evolution of target specificity in R1 clade non-LTR retrotransposons. Mol. Biol. Evol. 20:351-361.
18. Kozak, M. 1987. Effects of intercistronic length on the efficiency of reinitiation by eucaryotic ribosomes. Mol. Cell. Biol. 7:3438-3445.
19. Kozak, M. 1990. Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes. Proc. Natl. Acad. Sci. USA 87: 8301-8305.
20. Kozak, M. 1999. Initiation of translation in prokaryotes and eukaryotes. Gene 234:187-208.
21. Kozak, M. 2001. Constraints on reinitiation of translation in mammals. Nucleic Acids Res. 29:5226-5232.
22. Kubo, Y., S. Okazaki, T. Anzai, and H. Fujiwara. 2001. Structural and phylogenetic analysis of TRAS, telomeric repeat-specific non-LTR retrotransposon families in Lepidopteran insects. Mol. Biol. Evol. 18:848-857.
23. Luukkonen, B. G., W. Tan, and S. Schwartz. 1995. Efficiency of reinitiation of translation on human immunodeficiency virus type 1 mRNAs is determined by the length of the upstream open reading frame and by intercistronic distance. J. Virol. 69:4086-4094.
24. Malik, H. S., W. D. Burke, and T. H. Eickbush. 1999. The age and evolution of non-LTR retrotransposable elements. Mol. Biol. Evol. 16:793-805.
25. Malik, H. S., and T. H. Eickbush. 2001. Phylogenetic analysis of ribonuclease H domains suggests a late, chimeric origin of LTR retrotransposable elements and retroviruses. Genome Res. 11:1187-1197.
26. Matsumoto, T., H. Takahashi, and H. Fujiwara. 2003. Targeted nuclear import of open reading frame 1 protein is required for in vivo retrotransposition of a telomere-specific non-long terminal repeat retrotransposon, SART1. Mol. Cell. Biol. 24:105-122.
27. McMillan, J. P., and M. F. Singer. 1993. Translation of the human LINE-1 element, L1Hs. Proc. Natl. Acad. Sci. USA 90:11533-11537.
28. Meyers, G. 2003. Translation of the minor capsid protein of a calicivirus is initiated by a novel termination-dependent reinitiation mechanism. J. Biol. Chem. 278:34051-34060.
29. Osanai, M., H. Takahashi, K. K. Kojima, M. Hamada, and H. Fujiwara. 2004. Essential motifs in the 3′ untranslated region required for retrotransposition and the precise start of reverse transcription in non-long-terminal-repeat retrotransposon SART1. Mol. Cell. Biol. 24:7902-7913.
30. Peabody, D. S. 1989. Translation initiation at non-AUG triplets in mammalian cells. J. Biol. Chem. 264:5031-5035.
31. Peabody, D. S., and P. Berg. 1986. Termination-reinitiation occurs in the translation of mammalian cell mRNAs. Mol. Cell. Biol. 6:2695-2703.
32. Pestova, T. V., V. G. Kolupaeva, I. B. Lomakin, E. V. Pilipenko, I. N. Shatsky, V. I. Agol, and C. U. Hellen. 2001. Molecular mechanisms of translation initiation in eukaryotes. Proc. Natl. Acad. Sci. USA 98:7029-7036.
33. Sprengel, R., B. Reiss, and H. Schaller. 1985. Translationally coupled initiation of protein synthesis in Bacillus subtilis. Nucleic Acids Res. 13:893-909.
34. Szabo, G., Z. Katarova, and R. Greenspan. 1994. Distinct protein forms are produced from alternatively spliced bicistronic glutamic acid decarboxylase mRNAs during development. Mol. Cell. Biol. 14:7535-7545.
35. Takahashi, H., and H. Fujiwara. 1999. Transcription analysis of the telomeric repeat-specific retrotransposons TRAS1 and SART1 of the silkworm Bombyx mori. Nucleic Acids Res. 27:2015-2021.
36. Takahashi, H., and H. Fujiwara. 2002. Transplantation of target site specificity by swapping the endonuclease domains of two LINEs. EMBO J. 21: 408-417.
37. Takahashi, H., S. Okazaki, and H. Fujiwara. 1997. A new family of site-specific retrotransposons, SART1, is inserted into telomeric repeats of the silkworm, Bombyx mori. Nucleic Acids Res. 25:1578-1584.
38. Wilson, J. E., M. J. Powell, S. E. Hoover, and P. Sarnow. 2000. Naturally occurring dicistronic cricket paralysis virus RNA is regulated by two internal ribosome entry sites. Mol. Cell. Biol. 20:4990-4999.