Complement regulation during pregnancy

Immunologic Research

Volumn 32, Issue 1-3, 2005, Pages 187-192

  Molina, Hector ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Complement; Complement regulation; Fetal loss; Innate immunity; Pregnancy

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C5A; COMPLEMENT MEMBRANE ATTACK COMPLEX; PROTEIN CRRY; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ANGIOGENESIS; CELL PROTECTION; COMPLEMENT ACTIVATION; GLOMERULONEPHRITIS; HEYMANN NEPHRITIS; HUMAN; IMMUNOREGULATION; INFLAMMATION; INFLAMMATORY CELL; INNATE IMMUNITY; MOLECULAR MECHANICS; NONHUMAN; PHENOTYPE; PLACENTA; PREGNANCY; PREGNANCY DISORDER; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN SYNTHESIS; REVIEW; SURVIVAL; TISSUE INJURY;

ANIMALS; COMPLEMENT ACTIVATION; COMPLEMENT C3; COMPLEMENT SYSTEM PROTEINS; FEMALE; FETAL DEATH; HUMANS; IMMUNITY, NATURAL; MALE; MICE; MICE, KNOCKOUT; PHENOTYPE; PREGNANCY; RECEPTORS, COMPLEMENT;

EID: 23844436894     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1385/IR:32:1-3:187     Document Type: Review

References (29)

1. Schmidt BZ, Colten HR: Complement: a critical test of its biological importance. Immunol Rev 2000;178:166-176.
2. Molina H: Complement and immunity. Rheum Dis Clin N Am 2004;30:1-18.
3. Hourcade D, Holers VM, Atkinson JP: The regulators of complement activation (RCA) gene cluster. Adv Immunol 1989;45:381-416.
4. Lublin DM, Atkinson JP: Decay-accelerating factor and membrane cofactor protein. Curr Top Microbiol Immunol 1989;153:123-145.
5. Tsujimura A, Shida K, Kitamura M, et al: Molecular cloning of a murine homologue of membrane cofactor protein (CD46): preferential expression in testicular germ cells. Biochem J 1998;330:163-168.
6. Wong W, Fearon DT: P65: a C3b-binding protein on murine cells that shares antigenic determinants with the human C3b receptor (CR1) and is distinct from murine C3b receptor. J Immunol 1985;134:4048-4056.
7. Paul MS, Aegerter M, O'Brien SE, Kurtz CB, Weis JH: The murine complement receptor gene family I: analysis of mCRY gene products and their homology to human CR1. J Immunol 1989;142:582-589.
8. Molina H, Wong W, Kinoshita T, Brenner C, Foley S, Holers VM: Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1. J Exp Med 1992;175:121-129.
9. Kim Y-U, Kinoshita T, Molina H, et al: Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein. J Exp Med 1995;181:151-159.
10. Seya T, Hara T, Matsumoto M, Sugita Y, Akedo H: Complement-mediated tumor cell damage induced by antibodies against membrane cofactor protein (MCP,CD46). J Exp Med 1990;172:1673-1680.
11. Seya T, Kojima A, Hara T, Hazeki K, Sugita Y, Akedo H: Enhancement of lymphocyte-mediated K562 cytotoxicity by antibodies against complement membrane cofactor protein (CD46) and decay-accelerating factor (CD55). Immunobiology 1991;183:115-124.
12. Quigg RJ, Morgan BP, Holers VM, Adler S, Sneed AE, Lo CF: Complement regulation in rat glomerulus: Crry and CD59 regulate complement in glomerular mesangial and endothelial cells. Kidney Int 1995;48:412-421.
13. Nomura A, Nishikawa K, Yuzawa Y, et al: Tubulointerstitial injury induced in rats by a monoclonal antibody that inhibits function of a membrane inhibitor of complement. J Clin Invest 1995;96:2348-2356.
14. Matsuo S, Ichida S, Takizawa H, et al: In vivo effects of monoclonal antibodies that functionally inhibit complement regulatory proteins in rats. J Exp Med 1994;180:1619-1627.
15. McCurry KR, Kooyman DL, Diamond LE, Byrne GW, Logan JS, Platt J: Transgenic expression of human complement regulatory proteins in mice results in diminished complement deposition during organ xenoperfusion. Transplantation 1995;59:1177-1182.
16. Quigg RJ, Kozono Y, Berthiaume D, et al: Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor. J Immunol 1998;160:4553-4560.
17. Schiller B, He C, Salant DJ, Lim A, Alexander JJ, Quigg R: Inhibition of complement regulation is key to the pathogenesis of Heymann nephritis. J Exp Med 1998;188:1353-1358.
18. Xu C, Mao D, Holers MV, Palanca B, Cheng AM, Molina H: A critical role for murine complement regulator Crry in fetomaternal tolerance. Science 2000;287:498-501.
19. Billington WD: The normal fetomaternal immune relationship. Baillière's Clin Obstet Gynaecol 1992;6:417-438.
20. Mao D, Wu X, Deppong C, et al: Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway. Immunity 2003;19:813-822.
21. Rinkenberger J, Werb Z: The labyrinthine placenta. Nat Genet 2000;25:248-250.
22. Kingdom J, Huppertz B, Seaward G, Kaufmann P: Development of the placental villous tree and its consequences for fetal growth. Eur J Obstet Gynecol Reprod Biol 2000;92:35-43.
23. Cross JC: Genetic insights into trophoblast differentiation and placental morphogenesis. Cell Dev Biol 2000;11:105-113.
24. Hill JA: Immunological contributions to recurrent pregnancy loss. Baillière's Clin Obstet Gynaecol 1992;6:489-505.
25. Vince GS, Johnson PM: Materno-fetal immunobiology in normal pregnancy and its possible failure in recurrent spontaneous abortion? Hum Reprod 1995;10:107-113.
26. McIntyre JA: Immune recognition at the maternal-fetal interface: overview. Am J Reprod Immunol 1992;28:127-131.
27. Rooney IA, Oglesby TJ, Atkinson JP: Complement in human reproduction: activation and control. Immunol Res 1993;12:276-294.
28. Holmes CH, Simpson KL: Complement and pregnancy: new insights into the immunobiology of the fetomaternal relationship. Baillière's Clin Obstet Gynaecol 1992;6:439-460.
29. Holers VM, Girardi G, Mo L, et al: Complement C3 activation is required for the antiphospholipid antibody-induced fetal loss. J Exp Med 2002;195:211-220.