Growth hormone treatment of short stature: Status of the quality of life rationale

Hormone Research

Volumn 63, Issue 6, 2005, Pages 275-283

  Sandberg, David E ^a,b   Colsman, Melissa ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b CHILDREN S HOSPITAL OF BUFFALO   (United States)

Author keywords

Growth hormone treatment of short stature; Juvenilization; QoL assumptions regarding short stature; rhGH therapy, informed consent; Short stature; Stature related stereotypes; Stigmatization, psychosocial adaptation

Indexed keywords

RECOMBINANT GROWTH HORMONE;

ADAPTATION; ADOLESCENCE; ADULTHOOD; BEHAVIOR DISORDER; BODY HEIGHT; CHILDHOOD; CLINICAL TRIAL; COPING BEHAVIOR; EMPIRICAL RESEARCH; GROWTH RATE; HORMONAL THERAPY; HUMAN; INTELLIGENCE; MEDICAL ASSESSMENT; MEDICAL DECISION MAKING; MENTAL STRESS; OCCUPATION; PHYSICAL ATTRACTIVENESS; PHYSICAL DISABILITY; PREDICTION; PRIORITY JOURNAL; QUALITY OF LIFE; SELF ESTEEM; SHORT STATURE; SHORT SURVEY; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SOCIAL PROBLEM; SOCIAL PSYCHOLOGY; STEREOTYPY;

ADOLESCENT; ADULT; BODY HEIGHT; CHILD; FEMALE; GROWTH DISORDERS; HUMAN GROWTH HORMONE; HUMANS; MALE; PSYCHOLOGY; QUALITY OF LIFE;

EID: 23844433260     PISSN: 03010163     EISSN: None     Source Type: Journal    
DOI: 10.1159/000086593     Document Type: Short Survey

References (64)

1. Saenger P, Wikland KA, Conway GS, Davenport M, Gravholt CH, Hintz R, et al: Recommendations for the diagnosis and management of Turner syndrome. J Clin Endocrinol Metab 2001;86:3061-3069.
2. Vimalachandra D, Craig JC, Cowell CT, Knight JF: Growth hormone treatment in children with chronic renal failure: A meta-analysis of randomized controlled trials. J Pediatr 2001;139:560-567.
3. Cassidy SB: Prader-Willi syndrome in the new millennium. Endocrinologist 2001;10(suppl 1):1S-73S.
4. Sas T, de Waal W, Mulder P, Houdijk M, Jansen M, Reeser M, et al: Growth hormone treatment in children with short stature born small for gestational age: 5-year results of a randomized, double-blind, dose-response trial. J Clin Endocrinol Metab 1999;84:3064-3070.
5. Finkelstein BS, Imperiale TF, Speroff T, Marrero U, Radcliffe DJ, Cuttler L: Effect of growth hormone therapy on height in children with idiopathic short stature: A meta-analysis. Arch Pediatr Adolesc Med 2002;156:230-240.
6. Allen DB, Post N: hGH for short stature: Ethical issues raised by expanded access. J Pediatr 2004;144:648-652.
7. US Food and Drug Administration: FDA approves Humatrope for short stature. FDA Talk Paper. July 25, 2003. Available at: www.fda.gov/bbs/topics/ ANSWERS/2003/ANS01242.html. Accessed May 3, 2005.
8. Clopper R, Mazur T, Ellis AM, Michael P: Height and children's stereotypes; in Stabler B, Underwood LE (eds): Growth, Stature, and Adaptation. Chapel Hill, University of North Carolina at Chapel Hill, 1994, pp 7-18.
9. Martel LF, Biller H: Stature and Stigma: The Biopsychosocial Development of Short Males. Lexington, Lexington Books, 1987.
10. Jackson LA, Ervin KS: Height stereotypes of women and men: The liabilities of shortness for both sexes. J Soc Psychol 1992;132:433-445.
11. Gacsaly SA, Borges CA: The male physique and behavioral expectancies. J Psychol 1979;101:97-102.
12. Voss LD, Mulligan J: Bullying in school: Are short pupils at risk? Questionnaire study in a cohort. BMJ 2000;320:612-613.
13. Arkoff A, Weaver HB: Body image and body dissatisfaction in Japanese-Americans. J Soc Psychol 1966;68:323-330.
14. Rekers-Mombarg LT, Busschbach JJ, Massa GG, Dicke J, Wit JM: Quality of life of young adults with idiopathic short stature: Effect of growth hormone treatment. Acta Paediatr 1998;87:865-870.
15. Underwood LE: The social cost of being short: Societal perceptions and biases. Acta Paediatr Suppl 1991;377:3-8.
16. Eisenberg N, Roth K, Bryniarski KA, Murray E: Sex differences in the relationship of height to children's actual and attributed social and cognitive competencies. Sex Roles 1984;11:719-734.
17. Hartnett JJ, Bailey KG, Hartley CS: Body height, position, and sex as determinants of personal space. J Psychol 1974;87:129-136.
18. Bailey KG, Caffrey JV, Hartnett JJ: Body size as implied threat: Effects on personal space and person perception. Percept Mot Skills 1976;43:223-230.
19. Beigel HG: Body height in mate selection. J Soc Psychol 1954;39:257-268.
20. Graziano W, Brothen T, Berscheid E: Height and attraction: Do men and women see eye-to-eye? J Pers 1978;46:128-145.
21. Hensley WE: Height as a basis for interpersonal attraction. Adolescence 1994;29:469-474.
22. Pierce CA: Body height and romantic attraction: A meta-analytic test of the male-taller norm. Soc Behav Pers 1996;24:143-150.
23. Brackbill Y, Nevill DD: Parental expectations of achievement as affected by children's height. Merrill-Palmer Q 1981;27:429-441.
24. Wilson PR: Perceptual distortion of height as a function of ascribed academic status. J Soc Psychol 1968;74:97-102.
25. Lechelt EC: Occupational affiliation and ratings of physical height and personal esteem. Psychol Rep 1975;36:943-946.
26. Sandberg DE: Short stature: Intellectual and behavioral aspects; in Lifshitz F (ed): Pediatric Endocrinology, ed 3. New York, Dekker, 1996, pp 149-162.
27. Sandberg DE, Michael P: Psychosocial stresses related to short stature: Does their presence imply psychiatric dysfunction? In Drotar D (ed): Assessing Pediatric Health-Related Quality of Life and Functional Status: Implications for Research. Mahwah, Lawrence Erlbaum Assoc, 1998, pp 287-312.
28. Zimet GD, Cutler M, Litvene M, Dahms W, Owens R, Cuttler L: Psychological adjustment of children evaluated for short stature: a preliminary report. J Dev Behav Pediatr 1995;16:264-270.
29. Meyer-Bahlburg HFL: Short stature: Psychological issues; in Lifshitz F (ed): Pediatric Endocrinology. New York, Dekker, 1990, pp 173-196.
30. Gould MS, Wunsch-Hitzig R, Dohrenwend B: Estimating the prevalence of childhood psychopathology. A critical review. J Am Acad Child Psychiatry 1981;20:462-476.
31. Shaffer D, Fisher P, Dulcan MK, Davies M, Piacentini J, Schwab-Stone ME, et al: The NIMH Diagnostic Interview Schedule for Children Version 2.3 (DISC-2.3): Description, acceptability, prevalence rates, and performance in the MECA Study. Methods for the Epidemiology of Child and Adolescent Mental Disorders Study. J Am Acad Child Adolesc Psychiatry 1996;35:865-877.
32. Theunissen NC, Kamp GA, Koopman HM, Zwinderman KA, Vogels T, Wit JM: Quality of life and self-esteem in children treated for idiopathic short stature. J Pediatr 2002;140:507-515.
33. Sandberg DE, Brook AE, Campos SP: Short stature: a psychosocial burden requiring growth hormone therapy? Pediatrics 1994;94:832-840.
34. Stabler B, Clopper RR, Siegel PT, Stoppani C, Compton PG, Underwood LE: Academic achievement and psychological adjustment in short children. The National Cooperative Growth Study. J Dev Behav Pediatr 1994;15:1-6.
35. Steinhausen HC, Dorr HG, Kannenberg R, Malin Z: The behavior profile of children and adolescents with short stature. J Dev Behav Pediatr 2000;21:423-428.
36. Sandberg DE, Kranzler J, Bukowski WM, Rosenbloom AL: Psychosocial aspects of short stature and growth hormone therapy. J Pediatr 1999;135:133-134.
37. Gilmour J, Skuse D: Short stature - the role of intelligence in psychosocial adjustment. Arch Dis Child 1996;75:25-31.
38. Voss LD, Mulligan J: The short 'normal' child in school: Self-esteem, behavior and attainment before puberty (The Wessex Growth Study); in Stabler B, Underwood LE (eds): Growth, Stature and Adaptation. Chapel Hill, University of North Carolina at Chapel Hill Press, 1994, pp 47-64.
39. Downie AB, Mulligan J, Stratford RJ, Betts PR, Voss LD: Are short normal children at a disadvantage? The Wessex Growth Study. BMJ 1997;314:97-100.
40. Voss LD: Short but normal. Arch Dis Child 1999;81:370-371.
41. Ulph F, Betts P, Mulligan J, Stratford RJ: Personality functioning: the influence of stature. Arch Dis Child 2004;89:17-21.
42. Wilson DM, Hammer LD, Duncan PM, Dornbusch SM, Ritter PL, Hintz RL, et al: Growth and intellectual development. Pediatrics 1986;78:646-650.
43. Sandberg DE, Bukowski WM, Fung CM, Noll RB: Height and social adjustment: Are extremes a cause for concern and action? Pediatrics 2004;114:744-750.
44. Ekwo E, Gosselink C, Roizen N, Brazdziunas D: The effect of height on family income. Am J Hum Biol 1991;3:181-188.
45. Harper B: Beauty, stature and the labour market: A British cohort study. Oxford Bull Econ Statist 2000;62:771-800.
46. Sargent JD, Blanchflower DG: Obesity and stature in adolescence and earnings in young adulthood. Analysis of a British birth cohort. Arch Pediatr Adolesc Med 1994;148:681-687.
47. Persico N, Postlewaite RJ, Silverman D: The effect of adolescent experience on labor market outcomes: The case of height. J Polit Econ 2004;112:1019-1053.
48. Judge TA, Cable DM: The effect of physical height on workplace success and income: Preliminary test of a theoretical model. J Appl Psychol 2004;89:428-441.
49. Fu H, Goldman N: Incorporating health into models of marriage choice: Demographic and sociological perspectives. J Marriage Fam 1996;58:740-758.
50. Fu H, Goldman N: The association between health-related behaviours and the risk of divorce in the USA. J Biosoc Sci 2000;32:63-88.
51. Keltner D, Capps L, Kring AM, Young RC, Heerey EA: Just teasing: A conceptual analysis and empirical review. Psychol Bull 2001;127:229-248.
52. Warm TR: The role of teasing in development and vice versa. J Dev Behav Pediatr 1997;18:97-101.
53. Downie AB, Mulligan J, McCaughey ES, Stratford RJ, Betts PR, Voss LD: Psychological response to growth hormone treatment in short normal children. Arch Dis Child 1996;75:32-35.
54. Ross JL, Sandberg DE, Rose SR, Leschek EW, Baron J, Chipman JJ, et al: Psychological adaptation in children with idiopathic short stature treated with growth hormone or placebo. J Clin Endocrinol Metab 2004;89:4873-4878.
55. Wilson DM, McCauley E, Brown DR, Dudley R: Oxandrolone therapy in constitutionally delayed growth and puberty. Bio-Technology General Corporation Cooperative Study Group. Pediatrics 1995;96:1095-1100.
56. Strickland AL: Long-term results of treatment with low-dose fluoxymesterone in constitutional delay of growth and puberty and in genetic short stature. Pediatrics 1993;91:716-720.
57. Richman RA, Kirsch LR: Testosterone treatment in adolescent boys with constitutional delay in growth and development. N Engl J Med 1988;319:1563-1567.
58. Anonymous: Guidelines for the use of growth hormone in children with short stature. A report by the Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society. J Pediatr 1995;127:857-867.
59. Noeker M, Haverkamp F: Adjustment in conditions with short stature: A conceptual framework. J Pediatr Endocrinol Metab 2000;13:1585-1594.
60. Finkelstein BS, Singh J, Silvers JB, Marrero U, Neuhauser D, Cuttler L: Patient attitudes and preferences regarding treatment: GH therapy for childhood short stature. Horm Res 1999;51(suppl 1):67-72.
61. Singh J, Cuttler L, Shin M, Silvers JB, Neuhauser D: Medical decision-making and the patient: understanding preference patterns for growth hormone therapy using conjoint analysis. Medical Care 1998;36(suppl 8):AS31-AS45.
62. Kazdin AE: Research Design in Clinical Psychology, ed 4. Boston, Allyn & Bacon, 2003.
63. Eminson DM, Powell RP, Hollis S: Cognitive behavioral interventions with short statured boys: a pilot study; in Stabler B, Underwood LE (eds): Growth, Stature, and Adaptation. Chapel Hill, The University of North Carolina at Chapel Hill, 1994, pp 135-150.
64. Grimberg A, Kutikov JK, Cucchiara AJ: Sex differences in patients referred for evaluation of poor growth. J Pediatr 2005;146:212-216.