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Volumn 95, Issue 1, 2005, Pages 95-98

Effect of low molecular weight heparin and different heparin molecular weight fractions on the activity of the matrix-degrading enzyme aggrecanase: Structure-function relationship

Author keywords

Aggrecanase; Anti inflammatory; Anticancer; Heparin; Inflammation; Invasion; Low molecular weight heparin

Indexed keywords

AGGRECANASE; ENOXAPARIN; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN; RECOMBINANT TISSUE FACTOR PATHWAY INHIBITOR; STREPTAVIDIN; TINZAPARIN; DALTEPARIN; PROTEINASE; PROTEINASE INHIBITOR;

EID: 23844432006     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20398     Document Type: Article
Times cited : (12)

References (10)
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  • 6
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    • The structure of aggrecan fragments in human synovial fluid: Evidence for the involvement in osteoarthritis of a novel proteinease, which cleaves the Glu373-Ala 374 bond in the interglobular domain
    • Sandy JD, Flannery CR, Neame PJ, Lohmander LS. 1992. The structure of aggrecan fragments in human synovial fluid: Evidence for the involvement in osteoarthritis of a novel proteinease, which cleaves the Glu373-Ala 374 bond in the interglobular domain. J Clin Invest 89:1512-1516.
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  • 9
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    • The thrombspondin motif of aggrecanase-1 is critical for aggrecan substrate recognition and cleavage
    • Tortorella MD, Pratta M, Liu RQ, Abbaszade I, Ross H, Burn T, Arner E. 2000. The thrombspondin motif of aggrecanase-1 is critical for aggrecan substrate recognition and cleavage. J Biol Chem 275:25791-25797.
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  • 10
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    • ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain
    • Westling J, Fosang AJ, Last K, et al. 2002. ADAMTS4 cleaves at the aggrecanase site (Glu373-Ala374) and secondarily at the matrix metalloproteinase site (Asn341-Phe342) in the aggrecan interglobular domain. J Biol Chem 277:16059-16066.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.