Protective effect of L-carnitine against oxidative damage caused by experimental chronic aflatoxicosis in quail (Coturnix Coturnix)

Acta Veterinaria Hungarica

Volumn 53, Issue 3, 2005, Pages 319-324

  Citil, M ^a   Gunes, V ^a   Atakisi, O ^a   Ozcan, Ayla ^a   Tuzcu, M ^a   Dogan, A ^a  

^a KAFKAS UNIVERSITY   (Turkey)

Author keywords

Aflatoxicosis; L carnitine; Malondialdehyde; Quail; Reduced glutathione

Indexed keywords

AFLATOXIN; CARNITINE;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ARTICLE; BIRD DISEASE; CHEMICALLY INDUCED DISORDER; COTURNIX; DIET SUPPLEMENTATION; DRUG ANTAGONISM; DRUG EFFECT; LIPID PEROXIDATION; METABOLISM; MYCOTOXICOSIS;

AFLATOXINS; ANIMAL FEED; ANIMALS; CARNITINE; COTURNIX; DIETARY SUPPLEMENTS; LIPID PEROXIDATION; MYCOTOXICOSIS; POULTRY DISEASES;

COTURNIX; COTURNIX COTURNIX; PHASIANIDAE;

EID: 23844431918     PISSN: 02366290     EISSN: None     Source Type: Journal    
DOI: 10.1556/AVet.53.2005.3.5     Document Type: Article

References (22)

1. Arockia Rani, P. J. and Panneerselvam, C. (2001): L-carnitine as a free radical scavenger in aging. Exp. Gerontol. 36, 1713-1726.
2. Atroshi, F., Rizzo, A., Biese, L., Veijalainen, P., Saloniemi, H., Sankari, S. and Andersson, K. (1999): Fumonisin B1-induced DNA damage in rat liver and spleen: Effect of pre-treatment with coenzyme Q10, L-carnitine, α-tocopherol and selenium. Pharmacol. Res. 40, 459-467.
3. Beutler, E., Duran, O. and Kelley, B. M. (1963): Improved method for determination of blood glutathione. J. Lab. Clin. Med. 61, 882-888.
4. Bryden, W. L., Cumming, R. B. and Balnove, D. (1979): The influence of vitamin A status on the response of chickens to aflatoxin B1 and changes in liver lipid metabolism associated with aflatoxicosis. Br. J. Nutr. 41, 529-540.
5. Chang, C. F. and Hamilton, P. B. (1982): Experimental aflatoxicosis in young Japanese quail. Poultry Sci. 61, 869-874.
6. Fritz, I. B. and Arrigoni-Martelli, E. (1993): Sites of action of carnitine and its derivatives on the cardiovascular system. Interactions with membranes. Trends Pharmacol. Sci. 14, 355-360.
7. Galvano, F., Piva, A., Ritieni, A. and Galvano, G. (2001): Dietary strategies to counteract the effects of mycotoxins: a review. J. Food Protect. 64, 120-131.
8. Gutteridge, J. M. C. and Halliwell, B. (1990): The measurement and mechanism of lipid peroxidation in biological systems. Trends Biochem. Sci. 15, 129-135.
9. Ibrahim, I. K., Shareef, A. M. and Al-Joubory, K. M. (2000): Ameliorative effects of sodium bentonite on phagocytosis and Newcastle disease antibody formation in broiler chickens during aflatoxicosis. Res. Vet. Sci. 69, 119-122.
10. Kalaiselvi, P. and Panneerselvam, C. (1998): Effect of L-carnitine on the status of lipid peroxidation and antioxidants in aging rats. J. Nutr. Biochem. 9, 575-581.
11. Merkley, J. W., Maxwell, R. J., Phillips, J. G. and Huff, W. E. (1987): Hepatic fatty acid profiles in aflatoxin-exposed broiler chickens. Poultry Sci. 66, 59-67.
12. Mézes, M., Barta, M. and Nagy, G. (1998): Comparative investigation on the effect of T-2 mycotoxin on lipid peroxidation and antioxidant status in different poultry species. Res. Vet. Sci. 66, 19-23.
13. NRC (1984): Nutrient Requirements of Poultry. Washington, DC.
14. Rao, J. R., Sharma, N. N. and John, T. S. (1995): Influence of dietary aflatoxin on Eimeria uzura infection in Japanese quail. Vet. Parasitol. 56, 17-22.
15. Rastogi, R., Srivastava, A. K. and Rastogi, A. K. (2001): Long-term effect of aflatoxin B1 and lipid peroxidation in rat liver and kidney. Effect of picroliv and silymarin. Phytother. Res. 15, 307-310.
16. Rebouche, C. J. (1992): Carnitine function and requirements during the life cycle. FASEB J. 6, 3379-3386.
17. Rosa, C. A., Miazzo, R., Magnoli, C., Salvano, M., Chiac, S. M., Ferrero, S., Saenz, M., Carvalho, E. C. and Dalcero, A. (2001): Evaluation of the efficacy of bentonite from the south of Argentina to ameliorate the toxic effects of AF in broilers. Poultry Sci. 80, 139-144.
18. Shotwell, O. L., Hesseltine, C. V., Stubblefield, R. D. and Sorenson, W. G. (1966): Production of aflatoxin on rice. Applied Microbiol. 14, 425-429.
19. Souza, M. F., Tome, A. R. and Rao, V. S. (1999): Inhibition by the bioflavonoid ternatin on aflatoxin B1-induced lipid peroxidation in rat liver. J. Pharmacol. 51, 125-129.
20. SPSS for Windows, Release 6.0, Copyright SPSS, Inc., 1989-1993, June 17, 1993.
21. Verma, R. J. and Nair, A. (2001): Ameliorative effect of vitamin E on aflatoxin-induced lipid peroxidation in the testis of mice. Asian J. Androl. 3, 217-221.
22. Yoshoiko, T., Kawada, K. and Shimada, T. (1979): Lipid peroxidation in maternal and cord blood and protective mechanism against activated-oxygen toxicity in the blood. Am. J. Obstet. Gynecol. 135, 372-376.