Metallothionein-I/II double knockout mice are no more sensitive to the carcinogenic effects of nickel subsulfide than wild-type mice

International Journal of Toxicology

Volumn 24, Issue 4, 2005, Pages 215-220

  Waalkes, Michael P ^a   Liu, Jie ^a   Kasprzak, Kazimierz S ^b   Diwan, Bhalchandra A ^c  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

Author keywords

Carcinogenesis; Metallothionein Deficient; Mice; Nickel; Sarcoma

Indexed keywords

BINDING PROTEIN; METALLOTHIONEIN; METALLOTHIONEIN I; METALLOTHIONEIN II; NICKEL; NICKEL SUBSULFIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARCINOGENIC ACTIVITY; CONTROLLED STUDY; DISEASE MODEL; DISEASE PREDISPOSITION; DOSE TIME EFFECT RELATION; FIBROSARCOMA; MALE; METAL BINDING; METAL METABOLISM; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PROTEIN BINDING; SENSITIVITY ANALYSIS; TOXICITY; TUMOR GROWTH;

ANIMALS; BODY WEIGHT; CARCINOGENS; MALE; METALLOTHIONEIN; MICE; MICE, KNOCKOUT; NEOPLASMS, EXPERIMENTAL; NICKEL; TIME FACTORS;

ANIMALIA;

EID: 23744483864     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1080/10915810591000668     Document Type: Article

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