메뉴 건너뛰기




Volumn 19, Issue 2, 2005, Pages 135-139

Beyond the statins: New therapeutic perspectives in cardiovascular disease prevention

Author keywords

Combination lipid modifying therapy; High density lipoprotein cholesterol; Nicotinic acid; Statin

Indexed keywords

ANTIOXIDANT; FIBRIC ACID DERIVATIVE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NICOTINIC ACID; TRIACYLGLYCEROL;

EID: 23744466024     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10557-005-1049-z     Document Type: Review
Times cited : (23)

References (43)
  • 1
    • 0342981862 scopus 로고    scopus 로고
    • The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators
    • Sacks FM, Pfeffer MA, Moyle LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N Engl J Med 1996;335:1001-1009.
    • (1996) N Engl J Med , vol.335 , pp. 1001-1009
    • Sacks, F.M.1    Pfeffer, M.A.2    Moyle, L.A.3
  • 2
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998;339:1349-1357.
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 3
    • 0027987849 scopus 로고    scopus 로고
    • Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet 1999;344:1383-1389.
    • (1999) Lancet , vol.344 , pp. 1383-1389
  • 4
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
    • West of Scotland Coronary Prevention Study Group
    • Shepherd J, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med 1995;333:1301-1307.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3
  • 5
    • 0032572086 scopus 로고    scopus 로고
    • Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AF-CAPS/TexCAPS. Air Force/Texas Coronary Athersclerosis Prevention Study
    • Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AF-CAPS/TexCAPS. Air Force/Texas Coronary Athersclerosis Prevention Study. J Am Med Assoc 1998;279:1615-1622.
    • (1998) J Am Med Assoc , vol.279 , pp. 1615-1622
    • Downs, J.R.1    Clearfield, M.2    Weis, S.3
  • 6
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). J Am Med Assoc 2001;285:2486-2497.
    • (2001) J Am Med Assoc , vol.285 , pp. 2486-2497
  • 8
    • 0034680352 scopus 로고    scopus 로고
    • Effect of pravastatin on coronary disease events in subgroups defined by coronary risk factors. The Prospective Pravastatin Pooling Project
    • Sacks FM, Tonkin AM, Shepherd J, et al. Effect of pravastatin on coronary disease events in subgroups defined by coronary risk factors. The Prospective Pravastatin Pooling Project. Circulation 2000;102:1893-1900.
    • (2000) Circulation , vol.102 , pp. 1893-1900
    • Sacks, F.M.1    Tonkin, A.M.2    Shepherd, J.3
  • 9
    • 0037177205 scopus 로고    scopus 로고
    • Coronary heart disease in patients with low LDL-cholesterol: Benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factors
    • Sacks FM, Tonkin AM, Craven T, et al. Coronary heart disease in patients with low LDL-cholesterol: Benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factors. Circulation 2002;105:1424-1428.
    • (2002) Circulation , vol.105 , pp. 1424-1428
    • Sacks, F.M.1    Tonkin, A.M.2    Craven, T.3
  • 10
    • 0017384270 scopus 로고
    • High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study
    • Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med 1977;62:707-714.
    • (1977) Am J Med , vol.62 , pp. 707-714
    • Gordon, T.1    Castelli, W.P.2    Hjortland, M.C.3    Kannel, W.B.4    Dawber, T.R.5
  • 11
    • 0029759109 scopus 로고    scopus 로고
    • High-density lipoprotein cholesterol as a predictor of coronary heart disease risk: The PROCAM experience and pathophysiological implications for reverse cholesterol transport
    • Assmann G, Schulte H, von Eckardstein A, Huang Y. High-density lipoprotein cholesterol as a predictor of coronary heart disease risk: The PROCAM experience and pathophysiological implications for reverse cholesterol transport. Atherosclerosis 1996;124:S11-S20.
    • (1996) Atherosclerosis , vol.124
    • Assmann, G.1    Schulte, H.2    Von Eckardstein, A.3    Huang, Y.4
  • 12
    • 0023726344 scopus 로고
    • Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study
    • Manninen V, Elo MO, Frick MH, et al. Lipid alterations and decline in the incidence of coronary heart disease in the Helsinki Heart Study. J Am Med Assoc 1988;260:641-651.
    • (1988) J Am Med Assoc , vol.260 , pp. 641-651
    • Manninen, V.1    Elo, M.O.2    Frick, M.H.3
  • 13
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol
    • Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
    • Rubins HB, Robins SJ, Collins D, et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med 1999;341:410-418.
    • (1999) N Engl J Med , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 14
    • 0033549840 scopus 로고    scopus 로고
    • Drug treatment of lipid disorders
    • Knopp RH. Drug treatment of lipid disorders. N Engl J Med 1999;341;498-511.
    • (1999) N Engl J Med , vol.341 , pp. 498-511
    • Knopp, R.H.1
  • 15
    • 0035910051 scopus 로고    scopus 로고
    • Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S
    • Ballantyne CM, Olsson AG, Cook TJ, Mercuri MF, Pedersen TR, Kjekshus J. Influence of low high-density lipoprotein cholesterol and elevated triglyceride on coronary heart disease events and response to simvastatin therapy in 4S. Circulation 2001;104:3046-3051.
    • (2001) Circulation , vol.104 , pp. 3046-3051
    • Ballantyne, C.M.1    Olsson, A.G.2    Cook, T.J.3    Mercuri, M.F.4    Pedersen, T.R.5    Kjekshus, J.6
  • 16
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals. A randomised placebo-controlled trial
    • Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals. A randomised placebo-controlled trial. Lancet 2002;360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 17
    • 58149212612 scopus 로고
    • Distribution of lipids in 8,500 men with coronary artery disease
    • Department of Veterans Affairs HDL Intervention Trial Study Group
    • Rubins HB, Robins SJ, Collins D, et al. Distribution of lipids in 8,500 men with coronary artery disease. Department of Veterans Affairs HDL Intervention Trial Study Group. Am J Cardiol 1995;75:1196-1201.
    • (1995) Am J Cardiol , vol.75 , pp. 1196-1201
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 18
    • 0029166762 scopus 로고
    • Range of serum cholesterol valves in the population developing coronary artery disease
    • Kannel WB. Range of serum cholesterol valves in the population developing coronary artery disease. Am J Cardiol 1995;76:69C-77C.
    • (1995) Am J Cardiol , vol.76
    • Kannel, W.B.1
  • 19
    • 0028200951 scopus 로고
    • Factors associated with low and elevated plasma high density lipoprotein cholesterol and apolipoprotein A-I levels in the Framingham Offspring Study
    • Schaefer EJ, Lamon-Fava S, Ordovas JM, et al. Factors associated with low and elevated plasma high density lipoprotein cholesterol and apolipoprotein A-I levels in the Framingham Offspring Study. J Lipid Res 1994;35:871-882.
    • (1994) J Lipid Res , vol.35 , pp. 871-882
    • Schaefer, E.J.1    Lamon-Fava, S.2    Ordovas, J.M.3
  • 21
    • 0034746490 scopus 로고    scopus 로고
    • Proatherogenic role of elevated CE transfer from HDL to VLDL1 and dense LDL in type 2 diabetes. Impact of the degree of triglyceridemia
    • Guérin M, Le Goff W, Lassel TS, et al. Proatherogenic role of elevated CE transfer from HDL to VLDL1 and dense LDL in type 2 diabetes. Impact of the degree of triglyceridemia. Arterioscler Thromb Vasc Biol 2001;21:282-288.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 282-288
    • Guérin, M.1    Le Goff, W.2    Lassel, T.S.3
  • 22
    • 0026754428 scopus 로고
    • Relation of high-density lipoprotein cholesterol and triglycerides to incidence of atherosclerotic coronary artery disease (the PROCAM experience). Prospective Cardiovascular Mn̈ster Study
    • Assmann G, Schulte H. Relation of high-density lipoprotein cholesterol and triglycerides to incidence of atherosclerotic coronary artery disease (the PROCAM experience). Prospective Cardiovascular Mn̈ster Study. Am J Cardiol 1992;70:733-737.
    • (1992) Am J Cardiol , vol.70 , pp. 733-737
    • Assmann, G.1    Schulte, H.2
  • 23
    • 33645169657 scopus 로고    scopus 로고
    • International Task Force for Prevention of Coronary Heart Disease, http://www.chd-taskforce.de/guidelines/toc.htm
  • 24
    • 0036040929 scopus 로고    scopus 로고
    • Effects of fibrates on serum metabolic parameters
    • Elisaf M. Effects of fibrates on serum metabolic parameters. Curr Med Res Opin 2002;18:269-276.
    • (2002) Curr Med Res Opin , vol.18 , pp. 269-276
    • Elisaf, M.1
  • 25
    • 0344874601 scopus 로고    scopus 로고
    • Fibrates in 2003: Therapeutic action in atherogenic dyslipidaemia and future perspectives
    • Chapman MJ. Fibrates in 2003: Therapeutic action in atherogenic dyslipidaemia and future perspectives. Atherosclerosis 2003;171:1-13.
    • (2003) Atherosclerosis , vol.171 , pp. 1-13
    • Chapman, M.J.1
  • 26
    • 0342506477 scopus 로고    scopus 로고
    • Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol
    • Frick MH, Syvanne M, Nieminen MS, et al. Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol. Circulation 1997;96:2137-2143.
    • (1997) Circulation , vol.96 , pp. 2137-2143
    • Frick, M.H.1    Syvanne, M.2    Nieminen, M.S.3
  • 27
    • 0035941990 scopus 로고    scopus 로고
    • Effect of fenofibrate on progression of coronary artery disease in type 2 diabetes: The Diabetes Atherosclerosis Intervention Study, a randomised study
    • Diabetes Atherosclerosis Intervention Study Investigators. Effect of fenofibrate on progression of coronary artery disease in type 2 diabetes: The Diabetes Atherosclerosis Intervention Study, a randomised study. Lancet 2001;357:905-910.
    • (2001) Lancet , vol.357 , pp. 905-910
  • 28
    • 0035962077 scopus 로고    scopus 로고
    • Relation of gemfibrozil treatment and lipid levels with major coronary events. VA-HIT: A randomized controlled trial
    • Robins SJ, Collins D, Wittes JT, et al. Relation of gemfibrozil treatment and lipid levels with major coronary events. VA-HIT: A randomized controlled trial. J Am Med Assoc 2001;285:1585-1591.
    • (2001) J Am Med Assoc , vol.285 , pp. 1585-1591
    • Robins, S.J.1    Collins, D.2    Wittes, J.T.3
  • 30
    • 0038050331 scopus 로고    scopus 로고
    • Niacin as a component of combination therapy for dyslipidaemia
    • Miller M. Niacin as a component of combination therapy for dyslipidaemia. Mayo Clin Proc 2003;78:735-742.
    • (2003) Mayo Clin Proc , vol.78 , pp. 735-742
    • Miller, M.1
  • 31
    • 0026724433 scopus 로고
    • Differential effects of nicotinic acid in subjects with different LDL subclass patterns
    • Superko HR, Krauss RM. Differential effects of nicotinic acid in subjects with different LDL subclass patterns. Atherosclerosis 1992;95:69-76.
    • (1992) Atherosclerosis , vol.95 , pp. 69-76
    • Superko, H.R.1    Krauss, R.M.2
  • 32
    • 0016630250 scopus 로고
    • Clofibrate and niacin in coronary heart disease
    • Coronary Drug Project Research Group. Clofibrate and niacin in coronary heart disease. J Am Med Assoc 1975;231;360-381.
    • (1975) J Am Med Assoc , vol.231 , pp. 360-381
  • 33
    • 0023001772 scopus 로고
    • Fifteen year mortality in Coronary Drug Project patients: Long-term benefit with niacin
    • Canner PL, Berge KG, Wenger NK, et al. Fifteen year mortality in Coronary Drug Project patients: Long-term benefit with niacin. J Am Coll Cardiol 1986;8:1245-1255.
    • (1986) J Am Coll Cardiol , vol.8 , pp. 1245-1255
    • Canner, P.L.1    Berge, K.G.2    Wenger, N.K.3
  • 34
    • 0023910325 scopus 로고
    • Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid
    • Carlson LA, Rosenhamer G. Reduction of mortality in the Stockholm Ischaemic Heart Disease Secondary Prevention Study by combined treatment with clofibrate and nicotinic acid. Acta Med Scand 1988;223:405-418.
    • (1988) Acta Med Scand , vol.223 , pp. 405-418
    • Carlson, L.A.1    Rosenhamer, G.2
  • 35
    • 0025183769 scopus 로고
    • Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B
    • Brown G, Albers JJ, Fisher LD, et al. Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N Engl J Med 1990;323:1289-1298.
    • (1990) N Engl J Med , vol.323 , pp. 1289-1298
    • Brown, G.1    Albers, J.J.2    Fisher, L.D.3
  • 36
    • 0032530770 scopus 로고    scopus 로고
    • Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia
    • Guyton JR, Goldberg AC, Kreisberg RA, Sprecher DL, Superko HR, O'Connor CM. Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia. Am J Cardiol 1998;82:737-743
    • (1998) Am J Cardiol , vol.82 , pp. 737-743
    • Guyton, J.R.1    Goldberg, A.C.2    Kreisberg, R.A.3    Sprecher, D.L.4    Superko, H.R.5    O'Connor, C.M.6
  • 37
    • 0037086184 scopus 로고    scopus 로고
    • Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia
    • Kashyap ML, McGovern ME, Berra K, et al. Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia. Am J Cardiol 2002;89:672-678.
    • (2002) Am J Cardiol , vol.89 , pp. 672-678
    • Kashyap, M.L.1    McGovern, M.E.2    Berra, K.3
  • 38
    • 0035969564 scopus 로고    scopus 로고
    • Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease
    • Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-1592.
    • (2001) N Engl J Med , vol.345 , pp. 1583-1592
    • Brown, B.G.1    Zhao, X.Q.2    Chait, A.3
  • 39
    • 0030841001 scopus 로고    scopus 로고
    • Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations (Lipoprotein and Coronary Atherosclerosis Study [LCAS])
    • Herd JA, Ballantyne CM, Farmer JA, et al. Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations (Lipoprotein and Coronary Atherosclerosis Study [LCAS]). Am J Cardiol 1997;80:278-286.
    • (1997) Am J Cardiol , vol.80 , pp. 278-286
    • Herd, J.A.1    Ballantyne, C.M.2    Farmer, J.A.3
  • 40
    • 0032912006 scopus 로고    scopus 로고
    • Influence of low HDL on progression of coronary artery disease and response to fluvastatin therapy
    • Ballantyne CM, Herd JA, Ferlic LL, et al. Influence of low HDL on progression of coronary artery disease and response to fluvastatin therapy. Circulation 1999;99:736-743.
    • (1999) Circulation , vol.99 , pp. 736-743
    • Ballantyne, C.M.1    Herd, J.A.2    Ferlic, L.L.3
  • 41
    • 0028113715 scopus 로고
    • Lack of effect of lovastatin on restenosis after coronary angioplasty
    • Weintraub WS, Boccuzzi SJ, Klein JL, et al. Lack of effect of lovastatin on restenosis after coronary angioplasty. N Engl J Med 1994;331:1331-1337.
    • (1994) N Engl J Med , vol.331 , pp. 1331-1337
    • Weintraub, W.S.1    Boccuzzi, S.J.2    Klein, J.L.3
  • 42
    • 10044281651 scopus 로고    scopus 로고
    • Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2. a double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins
    • Taylor AJ, Sullenberger LE, Lee HJ, Lee JK, Grace KA. Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol (ARBITER) 2. A double-blind, placebo-controlled study of extended-release niacin on atherosclerosis progression in secondary prevention patients treated with statins. Circulation 2004;110:3512-3517.
    • (2004) Circulation , vol.110 , pp. 3512-3517
    • Taylor, A.J.1    Sullenberger, L.E.2    Lee, H.J.3    Lee, J.K.4    Grace, K.A.5
  • 43
    • 1342268255 scopus 로고    scopus 로고
    • Dyslipidaemia and diabetes - The clinical realities
    • Betteridge J. Dyslipidaemia and diabetes - the clinical realities. Br J Cardiol 2004;11(Suppl 2):S11-S15.
    • (2004) Br J Cardiol , vol.11 , Issue.2 SUPPL.
    • Betteridge, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.