메뉴 건너뛰기




Volumn 94, Issue 2, 2005, Pages 235-237

Clopidogrel "resistance" and statin cotreatment - Significant for cardiocoronary prevention in real life?

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; ATORVASTATIN; CLOPIDOGREL; CYCLIC AMP; CYTOCHROME P450 3A4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; PRASUGREL; PRAVASTATIN; PROSTACYCLIN; PURINE P2Y12 RECEPTOR; SIMVASTATIN; THROMBOXANE; UNCLASSIFIED DRUG;

EID: 23744463417     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH05-07-0468     Document Type: Editorial
Times cited : (6)

References (37)
  • 1
    • 0025280866 scopus 로고
    • Platelet hyperreactivity and prognosis in survivors of myocardial infarction
    • Trip MD, Cats VM, van Capelle FJ et al. Platelet hyperreactivity and prognosis in survivors of myocardial infarction. N Engl J Med 1990; 322: 1549-54.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1549-1554
    • Trip, M.D.1    Cats, V.M.2    van Capelle, F.J.3
  • 2
    • 10444281593 scopus 로고    scopus 로고
    • Variable extent of clopidogrel responsiveness in patients after coronary stenting
    • Grossmann R, Sokolova O, Schnurr A et al. Variable extent of clopidogrel responsiveness in patients after coronary stenting. Thromb Haemost 2004; 92: 1201-6.
    • (2004) Thromb. Haemost. , vol.92 , pp. 1201-1206
    • Grossmann, R.1    Sokolova, O.2    Schnurr, A.3
  • 3
    • 0038291914 scopus 로고    scopus 로고
    • Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement
    • Müller I, Besta F, Schulz C et al. Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement. Thromb Haemost 2003; 89: 783-7.
    • (2003) Thromb. Haemost. , vol.89 , pp. 783-787
    • Müller, I.1    Besta, F.2    Schulz, C.3
  • 4
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Matetzky S, Shenkman B, Guetta V et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation 2004; 109: 3171-5.
    • (2004) Circulation , vol.109 , pp. 3171-3175
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3
  • 5
    • 16844368927 scopus 로고    scopus 로고
    • A patient with stent thrombosis, clopidogrel-resistance and failure to metabolize clopidogrel to its active metabolite
    • Beckerath von N, Taubert D, Pogatsa-Murray G et al. A patient with stent thrombosis, clopidogrel-resistance and failure to metabolize clopidogrel to its active metabolite. Thromb Haemost 2005; 93: 789-91.
    • (2005) Thromb. Haemost. , vol.93 , pp. 789-791
    • Beckerath von, N.1    Taubert, D.2    Pogatsa-Murray, G.3
  • 6
    • 0036379817 scopus 로고    scopus 로고
    • Individual variations of platelet inhibition after loading doses of clopidogrel
    • Järemo P, Lindahl TL, Fransson SG et al. Individual variations of platelet inhibition after loading doses of clopidogrel. J Intern Med 2002; 252: 233-8.
    • (2002) J. Intern. Med. , vol.252 , pp. 233-238
    • Järemo, P.1    Lindahl, T.L.2    Fransson, S.G.3
  • 7
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting. Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • Gurbel PA, Bliden KP, Hiatt BL et al. Clopidogrel for coronary stenting. Response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation 2003; 107: 2908-13.
    • (2003) Circulation , vol.107 , pp. 2908-2913
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3
  • 8
    • 11844256436 scopus 로고    scopus 로고
    • Variability in platelet responsiveness to clopidogrel among 544 individuals
    • Serebruany VL, Steinhubl SR, Berger PB et al. Variability in platelet responsiveness to clopidogrel among 544 individuals. J Am Coll Cardiol 2005; 45: 246-51.
    • (2005) J. Am. Coll. Cardiol. , vol.45 , pp. 246-251
    • Serebruany, V.L.1    Steinhubl, S.R.2    Berger, P.B.3
  • 9
    • 33644577345 scopus 로고    scopus 로고
    • Ausmaß der Thrombozyteninhibition nach einer Initialdosis von 600 mg Clopidogrel und Prävalenz von Non-Respondern zum Zeitpunkt der Koronarintervention
    • Hochholzer W, Trenk D, Frundi D et al. Ausmaß der Thrombozyteninhibition nach einer Initialdosis von 600 mg Clopidogrel und Prävalenz von Non-Respondern zum Zeitpunkt der Koronarintervention. Z Kardiol 2004; 93: P1384.
    • (2004) Z Kardiol. , vol.93
    • Hochholzer, W.1    Trenk, D.2    Frundi, D.3
  • 10
    • 4444353174 scopus 로고    scopus 로고
    • Pharmacokinetics of clopidogrel after administration of a high loading dose
    • Taubert D, Kastrati A, Harlfinger S et al. Pharmacokinetics of clopidogrel after administration of a high loading dose. Thromb Haemost 2004; 92: 311-6.
    • (2004) Thromb. Haemost. , vol.92 , pp. 311-316
    • Taubert, D.1    Kastrati, A.2    Harlfinger, S.3
  • 11
    • 17444429227 scopus 로고    scopus 로고
    • P2Y12 gene H2 haplotype is not associated with increased adenosine diphosphate-induced platelet aggregation after initiation of clopidogrel therapy with a high loading dose
    • Beckerath von N, Beckerath von O, Koch W et al. P2Y12 gene H2 haplotype is not associated with increased adenosine diphosphate-induced platelet aggregation after initiation of clopidogrel therapy with a high loading dose. Blood Coagul Fibrinolysis 2005; 16: 199-204.
    • (2005) Blood Coagul. Fibrinolysis , vol.16 , pp. 199-204
    • Beckerath von, N.1    Beckerath von, O.2    Koch, W.3
  • 13
    • 14644439816 scopus 로고    scopus 로고
    • Existence of a clinically relevant interaction between clopidogrel and HMG-CoA reductase inhibitors? Reevaluating the evidence
    • Poulsen TS, Vinholt PM, Mickley H et al. Existence of a clinically relevant interaction between clopidogrel and HMG-CoA reductase inhibitors? Reevaluating the evidence. Basic Clin Pharmacol Toxicol 2005; 96: 103-10.
    • (2005) Basic. Clin. Pharmacol. Toxicol. , vol.96 , pp. 103-110
    • Poulsen, T.S.1    Vinholt, P.M.2    Mickley, H.3
  • 14
    • 0035197548 scopus 로고    scopus 로고
    • Identification of variants of CYP 3A4 and characterization of their abilities to metabolize testosterone and chlopyrifos
    • Dai D, Tang J, Rose R et al. Identification of variants of CYP 3A4 and characterization of their abilities to metabolize testosterone and chlopyrifos. J Pharmacol Exp Ther 2001; 299: 825-31.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 825-831
    • Dai, D.1    Tang, J.2    Rose, R.3
  • 15
    • 1642453779 scopus 로고    scopus 로고
    • Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance
    • Lau WC, Gurbel PA, Watkins PB et al. Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance. Circulation 2004; 109: 166-71.
    • (2004) Circulation , vol.109 , pp. 166-171
    • Lau, W.C.1    Gurbel, P.A.2    Watkins, P.B.3
  • 16
    • 0038508970 scopus 로고    scopus 로고
    • The metabolism of clopidogrel is catalyzed human cytochrome p450 3A and is inhibited by atorvastatin
    • Clarke TA, Waskell LA. The metabolism of clopidogrel is catalyzed human cytochrome p450 3A and is inhibited by atorvastatin. Drug Metab Dispos 2003; 31: 53-9.
    • (2003) Drug Metab. Dispos. , vol.31 , pp. 53-59
    • Clarke, T.A.1    Waskell, L.A.2
  • 17
    • 17644367866 scopus 로고    scopus 로고
    • Atorvastatin does not affect the pharmacokinetics of cyclosporine in renal transplant recipients
    • Hermann M, Asberg A, Christensen H et al. Atorvastatin does not affect the pharmacokinetics of cyclosporine in renal transplant recipients. Eur J Clin Pharmacol 2005; 61: 59-62.
    • (2005) Eur. J. Clin. Pharmacol. , vol.61 , pp. 59-62
    • Hermann, M.1    Asberg, A.2    Christensen, H.3
  • 18
    • 0037422534 scopus 로고    scopus 로고
    • Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation. A new drug-drug interaction
    • Lau WC, Waskell LA, Watkins PB et al. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation. A new drug-drug interaction. Circulation 2003; 107: 32-7.
    • (2003) Circulation , vol.107 , pp. 32-37
    • Lau, W.C.1    Waskell, L.A.2    Watkins, P.B.3
  • 19
    • 23744488517 scopus 로고    scopus 로고
    • The antiplatelet effect of clopidogrel is not attenuated by statin treatment in stable patients with ischemic heart disease
    • Vinholt P, Poulsen TS, Korsholm L et al. The antiplatelet effect of clopidogrel is not attenuated by statin treatment in stable patients with ischemic heart disease. Thromb Haemost 2005; 94: 438-43.
    • (2005) Thromb. Haemost. , vol.94 , pp. 438-443
    • Vinholt, P.1    Poulsen, T.S.2    Korsholm, L.3
  • 20
    • 7544244139 scopus 로고    scopus 로고
    • Antiplatelet effects of a 600 mg loading dose of clopidogrel are not attenuated in patients receiving atorvastatin or simvastatin for at least 4 weeks prior to coronary artery stenting
    • Gorchakova O, von Beckerath N, Gawaz M, et al. Antiplatelet effects of a 600 mg loading dose of clopidogrel are not attenuated in patients receiving atorvastatin or simvastatin for at least 4 weeks prior to coronary artery stenting. Eur Heart J 2004; 25: 1898-2002.
    • (2004) Eur. Heart. J. , vol.25 , pp. 1898-2002
    • Gorchakova, O.1    von Beckerath, N.2    Gawaz, M.3
  • 21
    • 1642410985 scopus 로고    scopus 로고
    • Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes
    • Mitsios JV, Papathanasiou AI, Rodis FI et al. Atorvastatin does not affect the antiplatelet potency of clopidogrel when it is administered concomitantly for 5 weeks in patients with acute coronary syndromes. Circulation 2004; 109: 1335-8.
    • (2004) Circulation , vol.109 , pp. 1335-1338
    • Mitsios, J.V.1    Papathanasiou, A.I.2    Rodis, F.I.3
  • 22
    • 0035421783 scopus 로고    scopus 로고
    • Profile and prevalence of aspirin resistance in patients with cardiovascular disease
    • Gum PA, Kottke-Marchant K, Poggio ED et al. Profile and prevalence of aspirin resistance in patients with cardiovascular disease. Am J Cardiol 2001; 88: 230-5.
    • (2001) Am. J. Cardiol. , vol.88 , pp. 230-235
    • Gum, P.A.1    Kottke-Marchant, K.2    Poggio, E.D.3
  • 23
    • 0037454168 scopus 로고    scopus 로고
    • A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease
    • Gum PA, Kottke-Marchant K, Welsh PA et al. A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease. J Am Coll Cardiol 2003; 41: 961-5.
    • (2003) J. Am. Coll. Cardiol. , vol.41 , pp. 961-965
    • Gum, P.A.1    Kottke-Marchant, K.2    Welsh, P.A.3
  • 24
    • 0032873146 scopus 로고    scopus 로고
    • Flow cytometric analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets - Definition and detection of clopidogrel/ticlopidine effects
    • Schwarz UR, Geiger J, Walter U et al. Flow cytometric analysis of intracellular VASP phosphorylation for the assessment of activating and inhibitory signal transduction pathways in human platelets - definition and detection of clopidogrel/ticlopidine effects. Thromb Haemost 1999; 82: 1145-52.
    • (1999) Thromb. Haemost. , vol.82 , pp. 1145-1152
    • Schwarz, U.R.1    Geiger, J.2    Walter, U.3
  • 25
    • 0038354521 scopus 로고    scopus 로고
    • Resistance to thienopyridines: Clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation
    • Barragan P, Bouvier J-L, Roquebert P-O et al. Resistance to thienopyridines: Clinical detection of coronary stent thrombosis by monitoring of vasodilator-stimulated phosphoprotein phosphorylation. Cathet Cardiovasc Intervent 2003; 59: 295-302.
    • (2003) Cathet. Cardiovasc. Intervent. , vol.59 , pp. 295-302
    • Barragan, P.1    Bouvier, J.-L.2    Roquebert, P.-O.3
  • 26
    • 15944383861 scopus 로고    scopus 로고
    • Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular disease
    • Aleil B, Ravanat C, Cazenave JP et al. Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular disease. J Thromb Haemost 2005; 3: 85-92.
    • (2005) J. Thromb. Haemost. , vol.3 , pp. 85-92
    • Aleil, B.1    Ravanat, C.2    Cazenave, J.P.3
  • 27
    • 0025026740 scopus 로고
    • Platelet reactivity and arachidonic acid metabolism in type II hyperlipoproteinemia and its modification by cholesterol-lowering agents
    • Schrör K. Platelet reactivity and arachidonic acid metabolism in type II hyperlipoproteinemia and its modification by cholesterol-lowering agents. Eicosanoids 1990; 3: 67-73.
    • (1990) Eicosanoids , vol.3 , pp. 67-73
    • Schrör, K.1
  • 28
    • 4544332598 scopus 로고    scopus 로고
    • ADP induced platelet degranulation in healthy individuals is reduced by clopidogrel after pretreatment with atorvastatin
    • Piorkowski M, Weikert U, Schwimmbeck PL et al. ADP induced platelet degranulation in healthy individuals is reduced by clopidogrel after pretreatment with atorvastatin. Thromb Haemost 2004; 92: 614-20.
    • (2004) Thromb. Haemost. , vol.92 , pp. 614-620
    • Piorkowski, M.1    Weikert, U.2    Schwimmbeck, P.L.3
  • 29
    • 20544450827 scopus 로고    scopus 로고
    • Impact of combined pharmacologic treatment with clopidogrel and a statin on outcomes of patients with non-ST-segment elevation acute coronary syndromes: Perspectives from a large multinational registry
    • Lim MJ, Spencer FA, Gore JM et al. Impact of combined pharmacologic treatment with clopidogrel and a statin on outcomes of patients with non-ST-segment elevation acute coronary syndromes: perspectives from a large multinational registry. Eur Heart J 2005; 26: 1963-9.
    • (2005) Eur. Heart. J. , vol.26 , pp. 1963-1969
    • Lim, M.J.1    Spencer, F.A.2    Gore, J.M.3
  • 30
    • 0024794147 scopus 로고
    • Simvastatin reduces platelet thromboxane formation and restores normal platelet sensitivity against prostacyclin in type IIa hypercholesterolemia
    • Schrör K, Löbel P, Steinhagen-Thiessen E. Simvastatin reduces platelet thromboxane formation and restores normal platelet sensitivity against prostacyclin in type IIa hypercholesterolemia. Eicosanoids 1989; 2: 39-46.
    • (1989) Eicosanoids , vol.2 , pp. 39-46
    • Schrör, K.1    Löbel, P.2    Steinhagen-Thiessen, E.3
  • 31
    • 0027495744 scopus 로고
    • The actions of lovastatin on platelet function and platelet eicosanoid receptors in type II hypercholesterolemia. A double-blind, placebo-controlled prospective study
    • Kaczmarek D, Hohlfeld T, Wambach G et al. The actions of lovastatin on platelet function and platelet eicosanoid receptors in type II hypercholesterolemia. A double-blind, placebo-controlled prospective study. Eur J Clin Pharmacol 1993; 45: 451-7.
    • (1993) Eur. J. Clin. Pharmacol. , vol.45 , pp. 451-457
    • Kaczmarek, D.1    Hohlfeld, T.2    Wambach, G.3
  • 32
    • 16644395324 scopus 로고    scopus 로고
    • Cholesterol-independent effects of statins and new therapeutic targets: Ischemic stroke and dementia
    • Miida T, Hirayama S, Nakamura Y. Cholesterol-independent effects of statins and new therapeutic targets: ischemic stroke and dementia. J Atheroscler Thromb 2004; 11: 253-64.
    • (2004) J. Atheroscler. Thromb. , vol.11 , pp. 253-264
    • Miida, T.1    Hirayama, S.2    Nakamura, Y.3
  • 33
    • 3042668784 scopus 로고    scopus 로고
    • New nonlipid effects of statins and their clinical relevance in cardiovascular disease
    • Undas A, Celinska-Lowenhoff M, Kaczor M et al. New nonlipid effects of statins and their clinical relevance in cardiovascular disease. Thromb Haemost 2004; 91: 1065-77.
    • (2004) Thromb. Haemost. , vol.91 , pp. 1065-1077
    • Undas, A.1    Celinska-Lowenhoff, M.2    Kaczor, M.3
  • 34
    • 8344231455 scopus 로고    scopus 로고
    • Aspirin and clopidogrel. Efficacy, safety, and the issue of drug resistance
    • Cattaneo M. Aspirin and clopidogrel. Efficacy, safety, and the issue of drug resistance. Arterioscler Thromb Vasc Biol 2004; 24: 1980-7.
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , pp. 1980-1987
    • Cattaneo, M.1
  • 35
    • 18044398749 scopus 로고    scopus 로고
    • Pharmacology of CS-747 (prasugrel, LY640315), a novel, potent antiplatelet agent with in vivo P2Y12 receptor antagonist activity
    • Niitsu Y, Jakubowski JA, Sugidachi A et al. Pharmacology of CS-747 (prasugrel, LY640315), a novel, potent antiplatelet agent with in vivo P2Y12 receptor antagonist activity. Semin Thromb Hemost 2005; 31: 184-94.
    • (2005) Semin. Thromb. Hemost. , vol.31 , pp. 184-194
    • Niitsu, Y.1    Jakubowski, J.A.2    Sugidachi, A.3
  • 36
    • 21044459487 scopus 로고    scopus 로고
    • A comparison of prasugrel (CS-747, LY640315) with clopidogrel on platelet function in healthy male volunteers
    • 87A
    • Asai F, Jakubowski et al. A comparison of prasugrel (CS-747, LY640315) with clopidogrel on platelet function in healthy male volunteers. JACC 2005; 45 (suppl 1): 87A 868-8.
    • (2005) JACC , vol.45 , Issue.SUPPL. 1 , pp. 868-878
    • Asai, F.1    Jakubowski2
  • 37
    • 24144437717 scopus 로고    scopus 로고
    • Inhibition of platelet aggregation with prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 receptor antagonist, compared with clopidogrel in aspirin-treated patients with atherosclerotic vascular disease
    • 416A
    • Wallentin L, Brandt JT. Inhibition of platelet aggregation with prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 receptor antagonist, compared with clopidogrel in aspirin-treated patients with atherosclerotic vascular disease. JACC 2005; 45 (suppl 1): 416A 1126-36.
    • (2005) JACC , vol.45 , Issue.SUPPL. 1 , pp. 1126-1136
    • Wallentin, L.1    Brandt, J.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.