Detection of cancerous endobrochial lesions by autofluorescence bronchoscopy combined with mutation analysis of p53

European Journal of Medical Research

Volumn 10, Issue 7, 2005, Pages 273-277

  Lang, Susanne M ^a,c   Ebelt, K ^a   Hautmann, H ^b   Stratakis, D F ^a   Huber, R M ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c Klinik Bad Reichenhall   (Germany)

Author keywords

Autofluorescence; Lung cancer; p53

Indexed keywords

PROTEIN P53; DNA;

ADULT; AGED; ARTICLE; AUTOFLUORESCENCE; BRONCHOSCOPY; BRONCHUS BIOPSY; BRONCHUS TUMOR; CANCER DIAGNOSIS; CANCER SCREENING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE COURSE; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HUMAN; INTERMETHOD COMPARISON; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG DYSPLASIA; LUNG METASTASIS; LUNG SQUAMOUS CELL CARCINOMA; MALE; MULTICENTER STUDY; MUTATIONAL ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR LOCALIZATION; FLUORESCENCE; GENETICS; LUNG CARCINOMA; LUNG TUMOR; MASS SCREENING; METASTASIS; METHODOLOGY; MIDDLE AGED; NUCLEOTIDE SEQUENCE; TUMOR SUPPRESSOR GENE;

BRONCHOSCOPY; CARCINOMA, BRONCHOGENIC; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; FLUORESCENCE; GENES, P53; HUMANS; LUNG NEOPLASMS; MALE; MASS SCREENING; MIDDLE AGED; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL;

EID: 23644448457     PISSN: 09492321     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Frost JK, Ball WC, Jr., Levin ML, Tockman MS, Baker RR, Carter D, Eggleston JC, Erozan YS, Gupta PK, Khouri NF, Marsh BR and Stitik FP (1984) Early lung cancer detection: results of the initial (prevalence) radiologic and cytologic screening in the Johns Hopkins study. Am Rev Respir Dis 130: 549-54
2. Haussinger K, Stanzel F, Huber RM, Pichler J and Stepp H (1999) Autofluorescence detection of bronchial tumors with the D-light/AF. Diagn Ther Endosc 5: 105-112
3. Hayata Y, Kato H, Ono J, Matsushima Y, Hayashi N, Saito T and Kawate N (1982) Fluorescence fiberoptic bronchoscopy in the diagnosis of early stage lung cancer. Recent Results Cancer Res 82: 121-130
4. Henschke CI, McCauley DI, Yankelevitz DF, Naidich DP, McGuinness G, Miettinen OS, Libby DM, Pasmantier MW, Koizumi J, Altorki NK and Smith JP (1999) Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancet 354: 99-105
5. Hirsch FR, Prindiville SA, Miller YE, Franklin WA, Dempsey EC, Murphy JR, Bunn PA and Kennedy TC (2001) Fluorescence Versus White-Light Bronchoscopy for Detection of Preneoplastic Lesions: a Randomized Study. J Natl Cancer Inst 93: 1385-1391
6. Hirsch FR, Franklin WA, Gazdar AF and Bunn PA (2001) Early Detection of Lung Cancer: Clinical Perspectives of Recent Advances in Biology and Radiology. Clin Cancer Res 7: 5-22
7. Husgafvel Pursiainen K, Boffetta P, Kannio A, Nyberg F, Pershagen G, Mukeria A, Constantinescu V, Fortes C and Benhamou S (2000) p53 mutations and exposure to environmental tobacco smoke in a multicenter study on lung cancer. Cancer Res 60: 2906-2911
8. Kakihana M, Il KK, Okunaka T, Furukawa K, Hirano T, Konaka C, Kato H and Ebihara Y (1999) Early detection of bronchial lesions using system of autofluorescence endoscopy (SAFE) 1000. Diagn Ther Endosc 5: 99-104
9. Kennedy TC, Lam S and Hirsch FR (2001) Review of recent advances in fluorescence bronchoscopy in early localization of central airway lung cancer. Oncologist 6: 257-262
10. Khanavkar B, Gnudi F, Muti A, Marek W, Muller KM, Atay Z, Topalidis T and Nakhosteen JA (1998) [Basic principles of LIFE - autofluorescence bronchoscopy. Results of 194 examinations in comparison with standard procedures for early detection of bronchial carcinoma - overview]. Pneumologie 52: 71-76
11. Kubik A, Parkin DM, Khlat M, Erban J, Polak J and Adamec M (1990) Lack of benefit from semi-annual screening for cancer of the lung: follow-up report of a randomized controlled trial on a population of high-risk males in Czechoslovakia. Int J Cancer 45: 26-33
12. Lam S, MacAulay C, Hung J, LeRiche J, Profio AE and Palcic B (1993) Detection of dysplasia and carcinoma in situ with a lung imaging fluorescence endoscope device. J Thorac Cardiovasc Surg 105: 1035-1040
13. Lam S, Kennedy T, Unger M, Miller YE, Gelmont D, Rusch V, Gipe B, Howard D, leRiche JC, Coldman A and Gazdar AF (1998) Localization of bronchial intraepithelial neoplastic lesions by fluorescence bronchoscopy. Chest 113: 696-702
14. Lam S, MacAulay C, leRiche JC and Palcic B (2000) Detection and localization of early lung cancer by fluorescence bronchoscopy. Cancer 89: 2468-2473
15. Lang SM, Heinzlmann M, Stratakis DF, Teschauer W and Loeschke K (1997) Detection of Ki-ras mutations by PCR and differential hybridization and of p53 mutations by SSCP analysis in endoscopically obtained lavage solution from patients with long-standing ulcerative colitis. Am J Gastroenterol 92: 2166-2170
16. Lang SM, Stratakis DF, Freudling A, Ebelt K, Oduncu F, Hautmann H and Huber RM (2000) Detection of K-ras and p53 mutations in bronchoscopically obtained malignant and non-malignant tissue from patients with non-small cell lung cancer. Eur J Med Res 5: 341-346
17. Marek W, Kotschy-Lang N, Muti A, Kohler CH, Nielsen L, Topalidis TH, Atay Z and Nakhosteen JA (2001) Can semi-automated image cytometry on induced sputum become a screening tool for lung cancer? Evaluation of quantitative semi-automated sputum cytometry on radon-and uranium-exposed workers. Eur Respir J 18: 942-950
18. McWilliams A, MacAulay C, Gazdar AF and Lam S (2002) Innovative molecular and imaging approaches for the detection of lung cancer and its precursor lesions. Oncogene 21: 6949-6959
19. Melamed MR, Flehinger BJ, Zaman MB, Heelan RT, Perchick WA and Martini N (1984) Screening for early lung cancer. Results of the Memorial Sloan-Kettering study in New York. Chest 86: 44-53
20. Parkin DM, Bray F, Ferlay J and Pisani P (2001) Estimating the world cancer burden: Globocan 2000. Int J Cancer 94: 153-156
21. Pasic A, Vonk-Noordegraaf A, Risse EK, Postmus PE and Sutedja TG (2003) Multiple suspicious lesions detected by autofluorescence bronchoscopy predict malignant development in the bronchial mucosa in high risk patients. Lung Cancer 41: 295-301
22. Rosell R, Taron M and O'Brate A (2001) Predictive molecular markers in non-small cell lung cancer. Curr Opin Oncol 13: 101-108
23. Sato M, Sakurada A, Sagawa M, Minowa M, Takahashi H, Oyaizu T, Okada Y, Matsumura Y, Tanita T and Kondo T (2001) Diagnostic results before and after introduction of autofluorescence bronchoscopy in patients suspected of having lung cancer detected by sputum cytology in lung cancer mass screening. Lung Cancer 32: 247-253
24. Satoh Y, Ishikawa Y, Nakagawa K, Hirano T and Tsuchiya E (1997) A follow-up study of progression from dysplasia to squamous cell carcinoma with immunohistochemical examination of p53 protein overexpression in the bronchi of ex-chromate workers. Br J Cancer 75: 678-683
25. Shibuya K, Hoshino H, Chiyo M, Iyoda S, Yoshida S, Sekine Y, Lizasa T, Saitoh Y, Baba M, Hiroshima K, Ohwada H and Fujisawa T (2003) High magnification bronchovideoscopy combined with narrow band imaging could detect capillary loops of angiogenic squamous dysplasia in heavy smokers at high risk for lung cancer. Thorax 58: 989-995
26. Sutedja TG, Codrington H, Risse EK, Breuer RH, van Mourik JC, Golding RP and Postmus PE (2001) Autofluorescence bronchoscopy improves staging of radiographically occult lung cancer and has an impact on therapeutic strategy. Chest 120: 1327-1332
27. Thiberville L, Payne P, Vielkinds J, LeRiche J, Horsman D, Nouvet G, Palcic B and Lam S (1995) Evidence of cumulative gene losses with progression of premalignant epithelial lesions to carcinoma of the bronchus. Cancer Res 55: 5133-5139