A short stereoselective synthesis of (R)-salmeterol

Synlett

Volumn , Issue 12, 2005, Pages 1948-1950

  Buchanan, David J ^a   Dixon, Darren J ^a   Looker, Brian E ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

lactol; 1,2 Amino alcohol; Asymmetric synthesis; oxy Michael addition

Indexed keywords

SALMETEROL;

AMINATION; ARTICLE; CATALYSIS; CHIRAL CHROMATOGRAPHY; DEPROTECTION REACTION; DIASTEREOISOMER; DRUG SYNTHESIS; HYDROLYSIS; MICHAEL ADDITION; POLYMERIZATION; REDUCTION; STEREOCHEMISTRY;

EID: 23644441571     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-871927     Document Type: Article

References (20)

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20. R = 21.84 min, 98.0% [R-isomer].