A mild, enantioselective synthesis of (R)-salmeterol via sodium borohydride–calcium chloride asymmetric reduction of a phenacyl phenylglycinol derivative

Journal of the Chemical Society. Perkin Transactions 1

Volumn 2, Issue 20, 2002, Pages 2237-2242

  Bream, Robert N ^a   Ley, Steven V ^a   McDermott, Benjamin ^b   Procopiou, Panayiotis A ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMATION; CHELATION; CHROMATOGRAPHY; COMPLEXATION; CONDENSATION REACTIONS; DERIVATIVES; ISOMERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REDUCTION; SYNTHESIS (CHEMICAL); TITRATION; X RAY DIFFRACTION ANALYSIS;

BROMOKETONE; CALCIUM CHLORIDE; HYDROGENOLYSIS; PHENACYL PHENYLGLYCINOL DERIVATIVE; SALMETEROL; SODIUM BOROHYDRIDE;

ORGANIC COMPOUNDS;

EID: 0036026458     PISSN: 14727781     EISSN: 13645463     Source Type: Journal    
DOI: 10.1039/b207068p     Document Type: Article

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