Sodium channel activators: Model of binding inside the pore and a possible mechanism of action

FEBS Letters

Volumn 579, Issue 20, 2005, Pages 4207-4212

  Tikhonov, Denis B ^a   Zhorov, Boris S ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Batrachotoxin; Channel block; Channel gating; Energy minimization; Ion permeation; Monte Carlo minimization; Veratridine

Indexed keywords

ACONITINE; BATRACHOTOXIN; GRAYANOTOXIN; LAPPACONITINE; N METHYLSTRYCHNINE; PANCURONIUM; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; SODIUM CHANNEL STIMULATING AGENT; UNCLASSIFIED DRUG; VERATRAMINE; VERATRIDINE;

ALLOSTERISM; ARTICLE; BINDING SITE; CHANNEL GATING; CRYSTAL STRUCTURE; DRUG STRUCTURE; HYDROPHILICITY; HYDROPHOBICITY; ION PERMEABILITY; ION TRANSPORT; MONTE CARLO METHOD; POROSITY; PRIORITY JOURNAL;

BATRACHOTOXINS; BINDING SITES; BIOLOGICAL TRANSPORT; CATIONS, MONOVALENT; LIGANDS; MODELS, MOLECULAR; SODIUM; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS; VERATRIDINE;

EID: 23644439944     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.07.017     Document Type: Article

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