Specific dose-dependent damage of Lieberkühn crypts promoted by large doses of type 2 ribosome-inactivating protein nigrin b intravenous injection to mice

Toxicology and Applied Pharmacology

Volumn 207, Issue 2, 2005, Pages 138-146

  Gayoso, M J ^a   Munoz R ^b   Arias, Y ^b   Villar, R ^c   Rojo, M A ^b   Jimenez P ^b   Ferreras, J M ^b   Aranguez, I ^d   Girbes T ^b  

^a UNIVERSITY OF VALLADOLID   (Spain)

^b UNIVERSITY OF VALLADOLID   (Spain)

^c HOSPITAL UNIVERSITARIO RÍO HORTEGA   (Spain)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Apoptosis; Nigrin b; Ribosome inactivating protein; Ricin; Small intestine; Stem cells

Indexed keywords

NIGRIN B; RIBOSOME INACTIVATING PROTEIN; RICIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BLEEDING; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYPT CELL; CYTOTOXICITY; DEATH; INTESTINE CRYPT; INTESTINE INJURY; INTESTINE VILLUS; MOUSE; NONHUMAN; STEM CELL;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INJECTIONS, INTRAVENOUS; INTESTINE, SMALL; MICE; N-GLYCOSYL HYDROLASES; PLANT PROTEINS; RICIN; STEM CELLS;

ANIMALIA;

EID: 23644435328     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2004.12.011     Document Type: Article

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