Simvastatin induces interleukin-18 production in human peripheral blood mononuclear cells

Clinical Immunology

Volumn 116, Issue 3, 2005, Pages 211-216

  Takahashi, Hideo Kohka ^a   Mori, Shuji ^a   Iwagaki, Hiromi ^a   Yoshino, Tadashi ^a   Tanaka, Noriaki ^a   Nishibori, Masahiro ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

3 Hydroxy 3 methylglutaryl coenzyme A; Human; Leukocyte function associated antigen; Peripheral blood mononuclear cells

Indexed keywords

CD40 ANTIGEN; CYTOKINE; GAMMA INTERFERON; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 12; INTERLEUKIN 18; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MEVALONIC ACID; SIMVASTATIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; HUMAN; HUMAN CELL; INHIBITION KINETICS; INTERFERON PRODUCTION; MONOCYTE; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ADULT; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD40; ANTIGENS, CD80; ANTIGENS, CD86; CD40 LIGAND; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTERCELLULAR ADHESION MOLECULE-1; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-18; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MEMBRANE GLYCOPROTEINS; MEVALONIC ACID; MIDDLE AGED; SIMVASTATIN; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 23444431956     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clim.2005.04.007     Document Type: Article

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