Synthesis of Dialkyl 1,4-Dihydro-2,6-dimethylpyridine-3,5-dicarboxylates and Alkyl 1,4-Dihydro-2,6-dimethyl-3-nitropyridine-5-carboxylates Possessing a C-4 2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl (uracil) Substituent to Determine Calcium Channel Modulation Structure-Activity Relationships

Journal of Heterocyclic Chemistry

Volumn 41, Issue 2, 2004, Pages 263-266

  Fassihi, Afshin ^a   Velazquez, Carlos ^a   Knaus, Edward E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 3 NITROPYRIDINE 5 CARBOXYLATE DERIVATIVE; 1,4 DIHYDRO 2,6 DIMETHYLPYRIDINE 3,5 DICARBOXYLATE DERIVATIVE; 3 AMINOCROTONATE; 5 FORMYLURACIL; ACETOACETIC ACID; ACETONE; AMMONIUM DERIVATIVE; AMMONIUM HYDROXIDE; CALCIUM CHANNEL AFFECTING AGENT; CROTONIC ACID DERIVATIVE; DIISOPROPYL 1,4 DIHYDRO 2,6 DIMETHYL 4 (2,4 DIOXO 1,2,3,4 TETRAHYDROPYRIMIDIN 5 YL)PYRIDINE 3,5 DICARBOXYLATE; ISOBUTYL 1,4 DIHYDRO 2,6 DIMETHYL 3 NITRO 4 (2,4 DIOXO 1,2,3,4 TETRAHYDROPYRIMIDIN 5 YL)PYRIDINE 5 CARBOXYLATE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; GUINEA PIG; HEART MUSCLE CONTRACTILITY; IN VITRO STUDY; INOTROPISM; NONHUMAN; POLYMERIZATION; SMOOTH MUSCLE; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION;

EID: 2342646358     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570410218     Document Type: Article

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