Effect of capsaicin on cholecystokinin and neuropeptide Y expressions in the brain of high-fat diet fed rats

Journal of Veterinary Medical Science

Volumn 66, Issue 2, 2004, Pages 107-114

  Park, Eun Sung ^a   Jo, Seona ^a   Yi, Seong Joon ^b   Kim, Jin Sang ^c   Lee, Heungshik S ^a   Lee, In Se ^a   Seo, Kang Moon ^a   Sung, Je Kyung ^a   Lee, Inhyung ^d   Yoon, Yeo Sung ^a  

^a Seoul National University   (South Korea)

^b Kyungpook National University   (South Korea)

^c Daegu University   (South Korea)

^d OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

Author keywords

Capsaicin; Cholecystokinin; High fat diet; Immunohistochemistry; Neuropeptide Y

Indexed keywords

ANIMALIA; CAPSICUM FRUTESCENS;

CAPSAICIN; CHOLECYSTOKININ; NEUROPEPTIDE Y;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; BRAIN; COMPARATIVE STUDY; DRUG EFFECT; FAT INTAKE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT; WEIGHT GAIN;

ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CAPSAICIN; CHOLECYSTOKININ; DIETARY FATS; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; NEUROPEPTIDE Y; RATS; RATS, SPRAGUE-DAWLEY; WEIGHT GAIN;

EID: 2342634393     PISSN: 09167250     EISSN: None     Source Type: Journal    
DOI: 10.1292/jvms.66.107     Document Type: Article

References (44)

1. Allen, Y. S., Adrian, T. E., Allen, J. M., Totemoto, K., Crow, T. J., Bloom, S. R. and Polak, J. M. 1983. Neuropeptide Y distribution in the rat brain. Science 221: 877-879.
2. Adrian, T. E., Allen, J. M., Bloom, S. R., Ghatei, M. A., Rossor, M. N., Roberts, G. W., Crow, T. J., Tatemoto, K. and Polak, J. M. 1983. Neuropeptide Y distribution in human brain. Nature (Lond.) 306: 584-586.
3. Barrachina, M. D., Martinez, V., Wang, L., Wei, J. Y. and Tache, Y. 1997. Synergistic interaction between leptin and cholecystokinin to reduce short-term food intake in lean mice. Proc. Natl. Acad. Sci. U.S.A. 94: 10455-10460.
4. Beck, B., Jhanwar-Uniyal, M., Burlet, A., Chapleur-Chateau, M., Leibowitz, S. F. and Burlet, C. 1990. Rapid and localized alterations of neuropeptide Y in discrete hypothalamic nuclei with feeding status. Brain Res. 528: 245-249.
5. Billington, C. J., Briggs, J. E., Grace, M. and Levine, A. S. 1991. Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism. Am. J. Physiol. 260: R321-327.
6. Choo, J. J. and Shin, H. J. 1999. Body-fat suppressive effects of capsaicin through β-adrenergic stimulation in rats fed a high-fat diet. Kor. J. Nutrition. 32: 533-539.
7. Chronwall, B. M., Diamaggio, D. A., Massari, V. J., Pickel, V. M., Ruggiero, D. A. and Odonohue, T. L. 1985. The anatomy of neuropeptide-Y- containing neurons in rat brain. Neuroscience 15: 1159-1181.
8. Della-Fera, M. A. and Baile, C. A. 1979. Cholecystokinin octapeptide: continuous picomole injections into the cerebral ventricles suppress feeding. Science 206: 471-473.
9. Della-Fera, M. A., Coleman, B. D., Doubek, C. A., Marshall, H. N., Paterson, J., Gingerich, R. L. and Baile, C. A. 1989. Cholecystokinin concentration in specific brain areas of rats fed during the light or dark phase of the circadian cycle. Physiol. Behav. 45: 801-807.
10. Della-Fera, M. A., Koch, J., Gingerich, R. L. and Baile, C. A. 1990. Intestinal infusion of a liquid diet alters CCK and NPY concentrations in specific brain areas of rats. Physiol. Behav. 48: 423-428.
11. Erickson, J. C., Clegg, K. E. and Palmiter, R. D. 1996. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature(Lond.) 381: 415-421.
12. Farook, J. M., Zhu, Y. J., Wang, H., Moochhala, S., Leeand, L. and Wong, P. T. 2001. Strain differences in freezing behavior of PVG hooded and Sprague-Dawley rats. Neuroerport 12: 2717-2720.
13. Gibbs, J., Young, R. C. and Smith, G. P. 1973a. Cholecystokinin decreases food intake in rats. J. Comp. Physiol. Psychol. 84: 488-495.
14. Gibbs, J., Young, R. C. and Smith, G. P. 1973b. Cholecystokinin elicits satiety in rats with open gastric fistulas. Nature (Lond.) 245: 323-325.
15. Hill, D. R., Campbell, N. J., Shaw, T. M. and Woodruff, G. N. 1987. Autoradiographic localization.
16. Houpt, T. R., Anika, S. M. and Wolff, N. C. 1978. Satiety effects of cholecystokinin and caerulein in rabbits. Am. J. Physiol. 235: R23-R28.
17. Ivy, A. C. and Oldberg, E. 1928. A hormone mechanism for gall-bladder contraction and evacuation. Am. J. Physiol. 86: 599-613.
18. John, T. C., Pushpa, S. K., William, R. C. and Satya, P. K. 1984. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 115: 427-429.
19. Kalra, S. P., Clark, J. T., Sahu, A., Dube, M. C. and Kalra, P. S. 1988. Control of feeding and sexual behaviors by neuropeptide Y: physiological implications. Synapse 2: 254-257.
20. Kawada, T., Hagihara, K. I. and Iwai, K. 1986. Effects of capsaicin on lipid metabolism in rats fed a high fat diet. J. Nutr. 116: 1272-1278.
21. Levine, A. S. and Morley, J. E. 1984. Neuropeptide Y: a potent inducer of consummatory behavior in rats. Peptides 5: 1025-1029.
22. Matson, C. A. and Ritter, R. C. 1999. Long-term CCK-leptin synergy suggests a role for CCK in the regulation of body weight. Am. J. Physiol. 276: R1038-1045.
23. Norman, A. W. 1987. pp. 322-354. Hormons. Academic Press, New York.
24. Nelson, E. K. and Dawson, L. E. 1923. The constitution of capsaicin, the pungent priciple of capsicum (III). J. Am. Chem. Soc. 45: 2179-2181.
25. Polkowska, J. and Gladysz, A. 2001. Effect of food manipulation on the neuropeptide Y neuronal system in the diencephalons of ewes. J. Chem. Neuroanat. 21: 149-159.
26. Sahu, A., Kalra, P. S. and Kalra, S. P. 1988. Food deprivation and ingestion induce reciprocal changes in neuropeptide Y concentrations in the paraventricular nucleus. Peptides 9: 83-86.
27. Sahu, A. 1998a. Evidince suggesting that galanin (GAL), melanin-concentrating hormone (MCH), neurotensin(NT), proopiomelanocortin (POMC) and neuropeptide Y (NPY) are targets of leptin signaling in the hypothalamus. Endocrinology 139: 795-798.
28. Sahu, A. 1998b. Leptin decreases food intake induced by melanin-concentrating hormone (MCH), galanin (GAL) and Neuropeptide Y (NPY) in the rat. Endocrinology 139: 4739-4742.
29. Saito, A., Williams, J. A. and Goldfine, I. D. 1981. Alteration in brain cholecystokinin receptors after fasting. Nature (Lond.) 289: 599-600.
30. Scallet, A. C., Della-Fera, M. A. and Baile, C. A. 1985. Satiety, hunger and regional brain content of cholecystokinin / gastrin and met-enkephalin immunoreactivity in sheep. Peptides 6: 937-943.
31. Schick, R. R., Harty, G. J., Yaksh, T. L. and Go, V. L. 1990. Sites in the brain at which cholecystokinin octapeptide (CCK-8) acts to suppress feeding in rats: mapping study. Neuropharmacology 29: 109-118.
32. Schick, R. R., Reilly, W. M., Roddy, D. R., Yaksh, T. L. and Go, V. L. 1987. Neuronal cholecystokinin-like immunoreactivity is postprandially released from primate hypothalamus. Brain Res. 418: 20-26.
33. Schwartz, M. W., Woods, S. C., Porte, D. Jr., Seeley, R. J. and Baskin, D. G. 2000. Central nervous system control of food intake. Nature (Lond.) 404: 661-671.
34. Schwartz, M. W. 2001. Brain pathways controlling food intake and body weight. Exp. Biol. Med. 226: 978-981.
35. Smith, G. P., Gibbs, J. and Young, R. C. 1974. Cholecystokinin and intestinal satiety in the rat. Fed. Proc. 33: 1146-1149.
36. Stacher, G., Bauer, H. and Steinringer, H. 1979. Cholecystokinin decreases appetite and activation evoked by stimuli arising from the preparation of a meal in man. Physiol. Behav. 23: 325-331.
37. Stanley, B. G., Daniel, D. R., Chin, A. S. and Leibowitz, S. F. 1985. Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion. Peptides 6: 1205-1211.
38. Stanley, B. G., Kyrkouli, S. E., Lampert, S. and Leibowitz, S. F. 1986. Neuropeptide Y chronically injected into the hypothalamus: a powerful neurochemical inducer of hyperphagia and obesity. Peptides 7: 1189-1192.
39. Stern, J. J., Cudillo, C. A. and Kruper, J. 1976. Ventromedial hypothalamus and short-term feeding suppression by caerulein in male rats. J. Comp. Physiol. Psychol. 90: 484-490.
40. Suzuki, T. and Iwai, K. 1984. Constituents of red pepper species: chemistry, biochemistry, pharmacology, and food science of the pungent principle of capsicum species, pp. 227-229. In: The Alkaloids, Academic Press, New York.
41. Swanson, L. W. 1992. pp. 45-123. Brain Maps: Structure of the Rat Brain, Elsevier Science Publishers B.V., Netherlands.
42. Tatemoto, K., Carlquist, M. and Mutt, V. 1982. Neuropeptide Y-a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide. Nature (Lond.) 296: 650-660.
43. Zhang, D. M., Bula, W. and Stellar, D. 1986. Brain cholecystokinin as a satiety peptide. Physiol. Behav. 36: 1183-1186.
44. Ziotopoulou, M., Mantzoros, C. S., Hileman, S. M. and Flier, J. S. 2000. Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice. Am. J. Physiol. 279: E838-E845.