Less IS less: A randomised controlled trial comparing cautious and rapid nalbuphine dosing regimens

Emergency Medicine Journal

Volumn 21, Issue 3, 2004, Pages 362-364

  Woollard, Malcolm ^a,b   Whitfield, R ^a   Smith, K ^a   Jones, T ^a   Thomas, G ^a   Hinton, C ^a  

^a WELSH AMBULANCE SERVICES NHS TRUST   (United Kingdom)

^b Welsh Ambulance Services NHS Trust ^*  (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NALBUPHINE;

ANALGESIC ACTIVITY; ARTICLE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DOSE RESPONSE; DROWSINESS; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG RESPONSE; HUMAN; MAJOR CLINICAL STUDY; MAXIMUM PERMISSIBLE DOSE; NAUSEA; OUTCOMES RESEARCH; PAIN ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SCORING SYSTEM; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; THORAX PAIN; VOMITING;

ADULT; AGED; ANALGESIA; ANALGESICS, OPIOID; CHEST PAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; EMERGENCY MEDICAL SERVICES; FEMALE; HUMANS; MALE; MIDDLE AGED; NALBUPHINE; PAIN MEASUREMENT; WOUNDS AND INJURIES;

EID: 2342633276     PISSN: 14720205     EISSN: None     Source Type: Journal    
DOI: 10.1136/emj.2004.014324     Document Type: Article

References (16)

1. Stene JK, Stofberg L, MacDonald G, et al. Nalbuphine analgesia in the pre-hospital setting. Am J Emerg Med 1988;6:634-9.
2. Chambers JA, Guly HR. Prehospital intravenous nalbuphine administered by paramedics. Resuscitation 1994;27:153-8.
3. Jamidar HA, Crooks SW, Adgey AA. Nalbuphine versus diamorphine early in the course of suspected myocardial infarction. Eur Heart J 1987;8:597-602.
4. Nikoda VV, Lebedeva RN, Artamoshina MP, et al. Comparative evalauation of the use of nalbuphine and buprenoriphine in prehospital care. Anesteziol Reanimatol 1998;5:23-8.
5. Dempsey C. Nubain Audit. Ambulance UK 1996;11:6-7.
6. Woollard M, Jones T, Pitt K, et al. Hitting them where it hurts? Low dose nalbuphine therapy. Emerg Med J 2002;19:565-70.
7. Bolton JE, Wilkinson RC. Responsiveness of pain scales: a comparison of three pain intensity measures in chiropractic patients. J Manipulative Physiol Ther 1998;21:1-17.
8. Bondestam E, Hovgren K, Gaston JF, et al. Pain assessment by patients and nurses in the early phase of acute myocardial infarction. J Adv Nurs 1987;12:677-82.
9. Price DD, Bush FM, Long S, et al. A comparison of pain measurement characteristics of mechanical visual analogue and simple numerical rating scales. Pain 1994;56:217-26.
10. Ekblom A, Hansson P. Pain intensity measurements in patients with acute pain receiving afferent stimulation. J Neurol Neurosurg Psychiatry 1988;51:481-6.
11. Seymour RA. The use of pain scales in assessing the efficacy of analgesics in post-operative dental pain. Eur J Clin Pharmacol 1982;23:441-4.
12. Ohnhaus EE, Adler R. Methodological problems in the measurement of pain: a comparison between the verbal rating scale and the visual analogue scale. Pain 1975;1:379-84.
13. Moher D, Schulz KF, Altman DG, for the Consort Group. The Consort statement: revised recommendations for improving the quality of reports of parallel-group randomised trials. Lancet 2001;357:1191-4.
14. Houlihan KP, Mitchell RG, Flapan AD, et al. Excessive morphine requirements after pre-hospital nalbuphine analgesia. J Accid Emerg Med 1999;16:29-31.
15. Bailey PL, Clark NJ, Pace NL, et al. Failure of nalbuphine to antagonize morphine: a double-blind comparison with naloxone. Anesth Analg 1986;65:605-11.
16. Kelly AS, Guly HR. Nalbuphine - the optimal pre-hospital analgesic for lower limb fractures? Pre-hospital Immediate Care 1999;3:224-5.