Is prolongation of the QTc interval during isoflurane anaesthesia more prominent in women pretreated with anthracyclines for breast cancer?

British Journal of Anaesthesia

Volumn 92, Issue 5, 2004, Pages 658-661

  Owczuk, R ^a   Wujtewicz, M A ^a   Sawicka, W ^a   Wujtewicz, M ^a   Swierblewski, M ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

Anaesthesia, general; Anaesthetics volatile, isoflurane; Chemotherapy, anticancer; Monitoring, electrocardiography, QT interval; Pharmacology, anthracyclines

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIRUBICIN; ETOMIDATE; FENTANYL; FLUOROURACIL; ISOFLURANE; MIDAZOLAM; NITROUS OXIDE; OXYGEN; VECURONIUM;

ADULT; ANESTHESIA INDUCTION; ANESTHETIC RECOVERY; ARTICLE; BREAST CANCER; BREAST SURGERY; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; ENDOTRACHEAL INTUBATION; FEMALE; HUMAN; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION; STANDARDIZATION; STATISTICAL SIGNIFICANCE;

EID: 2342631352     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aeh132     Document Type: Article

References (18)

1. Khan IA. Clinical and therapeutic aspects of congenital and acquired long QT syndrome. Am J Med 2002; 112: 58-66
2. Moss AJ. Measurement of the QT interval and the risk associated with QTc interval prolongation: a review. Am J Cardiol 1993; 72: 23B-25B
3. Dumaine R, Antzelevitch C. Molecular mechanisms underlying the long QT syndrome. Curr Opin Cardiol 2002; 17: 36-42
4. Chiang CE, Roden DM. The long QT syndromes: genetic basis and clinical implications. J Am Coll Cardiol 2000; 36: 1-12
5. Larsen RL, Jakacki RI, Vetter VL, Meadows AT, Silber JH, Barber G. Electrocardiographic changes and arrhythmias after cancer therapy in children and young adults. Am J Cardiol 1992; 70: 73-7
6. Meinardi MT, van Veldhuisen DJ, Gietema JA, et al. Prospective evaluation of early cardiac damage induced by epirubicin-containing adjuvant chemotherapy and locoregional radiotherapy in breast cancer patients. J Clin Oncol 2001; 19: 2746-53
7. Nousiainen T, Vanninen E, Rantala A, Jantunen E, Hartikainen J. QT dispersion and late potentials during doxorubicin therapy for non-Hodgkin's lymphoma. J Intern Med 1999; 245: 359-64
8. Wisely NA, Shipton EA. Long QT syndrome and anaesthesia. Eur J Anaesthesiol 2002; 19: 853-9
9. Booker PD, Whyte SD, Ladusnas EJ. Long QT syndrome and anaesthesia. Br J Anaesth 2003; 90: 349-66
10. Paventi S, Santevecchi A, Ranieri R. Effects of sevoflurane versus propofol on QT interval. Minerva Anestesiol 2001; 67: 637-40
11. Kleinsasser A, Loeckinger A, Lindner KH, Keller C, Boehler M, Puehringer F. Reversing sevoflurane-associated Q-Tc prolongation by changing to propofol. Anaesthesia 2001; 56: 248-50
12. Michaloudis D, Fraidakis O, Lefaki T, et al. Anaesthesia and the QT interval in humans. The effects of isoflurane and halothane. Anaesthesia 1996; 51: 219-24
13. Malik M, Batchvarow VN. Measurement, interpretation and clinical potential of QT dispersion. J Am Coll Cardiol 2000; 36: 1749-66
14. Benhorin J, Merri M, Alberti M, et al. Long QT syndrome. New electrocardiographic characteristics. Circulation 1990; 82: 521-7
15. Grenier MA, Lipshultz SE. Epidemiology of anthracycline cardiotoxicity in children and adults. Semin Oncol 1998; 25 (Suppl. 10): 72-85
16. Michaloudis D, Fraidakis O, Petrou A, Gigourtsi C, Parthenakis F. Anaesthesia and the QT interval. Effects of isoflurane and halothane in unpremedicated children. Anaesthesia 1998; 53: 435-9
17. Kleinsasser A, Kuenszberg E, Loeckinger A, et al. Sevoflurane, but not propofol, significantly prolongs the Q-T interval. Anesth Analg 2000; 90: 25-7
18. Viskin S. Long QT syndrome and torsade de pointes. Lancet 1999; 354: 1625-33