IONP-PLL: A novel non-viral vector for efficient gene delivery

Journal of Gene Medicine

Volumn 5, Issue 9, 2003, Pages 803-817

  Xiang, Juan Juan ^a   Tang, Jing Qun ^b   Zhu, Shi Guo ^a   Nie, Xin Min ^a   Lu, Hong Bin ^a   Shen, Shou Rong ^c   Li, Xiao Ling ^a   Tang, Ke ^a   Zhou, Ming ^a   Li, Gui Yuan ^a  

^a Central South University   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

CNS disease; Gene transfer; Iron oxide nanoparticles; Non viral gene vector

Indexed keywords

AGAROSE; ENHANCED GREEN FLUORESCENT PROTEIN; LIPOSOME; LUCIFERASE; MONOCRYSTALLINE IRON OXIDE NANOPARTICLE; PLASMID DNA; POLYLYSINE; DNA; FERRIC ION; FERRIC OXIDE; GREEN FLUORESCENT PROTEIN; PHOTOPROTEIN;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN NERVE CELL; BRAIN REGION; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; GENE THERAPY; GENETIC TRANSFECTION; GLIA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY PARENCHYMA; LUNG PARENCHYMA; MARKER GENE; MEDICAL RESEARCH; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; REPORTER GENE; SEDIMENTATION; SPLEEN; TRANSPORT KINETICS; ANIMAL; BRAIN; CHEMISTRY; FIBROBLAST; GENE TARGETING; GENE VECTOR; GENETICS; GLIA; KIDNEY; METABOLISM; METHODOLOGY; TISSUE DISTRIBUTION; TUMOR CELL LINE; ULTRASTRUCTURE;

ANIMALS; BRAIN; CELL LINE; CELL LINE, TUMOR; DNA; FERRIC COMPOUNDS; FIBROBLASTS; GENE TARGETING; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; KIDNEY; LUMINESCENT PROTEINS; MICE; NEUROGLIA; POLYLYSINE; TISSUE DISTRIBUTION; TRANSFECTION;

EID: 2342584873     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.419     Document Type: Article

References (34)

1. Felgner JH, Kumar R, Sridhar CN, et al. Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations. J Biol Chem 1994; 269: 2550-2561.
2. Van Craynest N, Santaella C, Boussif O, et al. Polycationic telomers and cotelomers for gene transfer: synthesis and evaluation of their in vitro transfection efficiency. Bioconjug Chem 2002; 13: 59-75.
3. Lau C, Soriano HE, Ledley FD, et al. Retroviral gene transfer into the intestinal epithelium. Hum Gene Ther 1995; 6 1145-1151.
4. Scollay R. Gene therapy: a brief overview of the past, present, and future. Ann N Y Acad Sci 2001; 953: 26-30.
5. Cohen H, Levy RJ, Gao J, et al. Sustained delivery and expression of DNA encapsulated in polymeric nanoparticles. Gene Ther 2000; 7: 1896-1905.
6. Engelhardt JF, Ye X, Doranz B, et al. Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liver. Proc Natl Acad Sci U S A 1994; 91: 6196-6200.
7. Niidome T, Ohmori N, Ichinose A, et al. Binding of cationic α-helical peptides to plasmid DNA and their gene transfer abilities into cells. J Biol Chem 1997; 272: 15 307-15 312.
8. Chan CK, Senden T, Jans DA. Supramolecular structure and nuclear targeting efficiency determine the enhancement of transfection by modified polylysine. Gene Ther 2000; 7: 1690-1697.
9. Aoki K, Furuhata S, Hatanaka K, et al. Polyethylenimine-mediated gene transfer into pancreatic tumor dissemination in the murine peritoneal cavity. Gene Ther 2001; 3 508-514.
10. Boussif O, Lezoualc'h F, Zanta MA, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci U S A 1995; 92: 7297-7301.
11. Junghans M, Kreuter J, Zimmer A. Antisense delivery using protamine-oligonucleotide particles. Nucleic Acids Res 2000; 28 E45.
12. Felgner PL, Gadek TR, Holm M, et al. Lipofection: a highly efficient, lipid-mediated DNA transfection procedure. Proc Natl Acad Sci U S A 1987; 84: 7413-7417.
13. Nabel GJ, Nabel EG, Yang ZY, et al. Direct gene transfer with DNA liposome complexes in melanoma expression, biological activity, and lack of toxicity in humans. Proc Natl Acad Sci U S A 1993; 90: 11307-11311.
14. Marshall J. The trouble with vectors. Science 1995; 269: 1015-1055.
15. Liu F, Qi H, Huang L, et al. Factor controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration. Gene Ther 1997; 8: 177-185.
16. Kneuer C, Sameti M, Haltner EG, et al. Silica nanoparticles modified with aminosilanes as carriers for plasmid DNA. Int J Pharmaceut 2000; 196: 257-261.
17. Ogirs M, Wagner E. Targeting tumors with non-viral gene delivery systems. Drug Discovery Today 2002; 7: 479-485.
18. Xiang JJ, Zhu SG, Li GY, et al. Using iron oxide nanoparticles as gene carrier. Chin J Cancer 2001; 20: 1-6.
19. Zimmer C, Weissleder R, Poss K, et al. MR imaging of phagocytosis in experimental gliomas. Radiology 1995; 197: 533-538.
20. Moore A, Marecos E, Bogdanov A Jr, et al. Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model. Radiology 2000; 214: 568-574.
21. Morris MC, Chaloin L, Mery J, et al. A novel potent strategy for gene delivery using a single peptide vector as a carrier. Nucleic Acids Res 1999; 27: 3510-3517.
22. Dash PR, Read ML, Barrett LB, et al. Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery. Gene Ther 1999; 6: 643-650.
23. Living Colors User Manual, Clontech Laboratories, Inc., Protocol #PT2040∼1, version #PR94845.
24. Shen T, Weissleder R, Papisov M, et al. Monocrystalline iron oxide nanocompounds (MION): physicochemical properties. Magn Reson Med 1993; 29: 599-604.
25. Neuwelt EA, Weissleder R, Nilaver G, et al. Delivery of virus-sized iron oxide particles to rodent CNS neurons. Neurosurgery 1994; 34: 777-784.
26. Zimmer C, Wright SC Jr, Engelhardt RT, et al. Tumor cell endocytosis imaging facilitates delineation of the glioma-brain interface. Exp Neurol 1997; 143: 61-69.
27. Luo D, Saltzman WM. Synthetic DNA delivery systems. Nat Biotechnol 2000; 18: 33-37.
28. Laurent N, Wattiaux-De Coninck S, Mihaylova E, et al. Uptake by rat liver and intracellular fate of plasmid DNA complexed with poly-L-lysine or poly-D-lysine. FEBS Lett 1999; 443: 61-65.
29. Shi N, Pardridge WM. Noninvasive gene targeting to the brain. Proc Natl Acad Sci U S A 2000; 97: 7567-7572.
30. Chiocca EA, Choi BB, Cai WZ, et al. Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants. New Biol 1990; 2: 739-746.
31. Zlokovic BV, Apuzzo ML. Cellular and molecular neurosurgery: pathways from concept to reality. II. Vector systems and delivery methodologies for gene therapy of the central nervous system. Neurosurgery 1997; 40: 805-812.
32. Culver KW, Ram Z, Wallbridge S, et al. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 1992; 256: 1550-1552.
33. Nilaver G, Muldoon LL, Kroll RA, et al. Delivery of herpesvirus and adenovirus to nude rat intracerebral tumors after osmotic blood-brain barrier disruption. Proc Natl Acad Sci U S A 1995; 92: 9829-9833.
34. Neuwelt EA, Barnett PA, Ramsey FL, et al. Dexamethasone decreases the delivery of tumor-specific monoclonal antibody to both intracerebral and subcutaneous tumor xenografts. Neurosurgery 1993; 33: 478-484.