Epinephrine (adrenaline) in the first-aid, out-of-hospital treatment of anaphylaxis

Novartis Foundation Symposium

Volumn 257, Issue , 2004, Pages 228-243

  Simons, F Estelle R ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ADRENERGIC RECEPTOR STIMULATING AGENT;

ADOLESCENT; ADULT; AGED; ANAPHYLAXIS; ANIMAL; ARTICLE; BLOOD PRESSURE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DOG; DRUG SELF ADMINISTRATION; FEMALE; FIRST AID; HUMAN; HYPERSENSITIVITY; INFANT; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PRESCHOOL CHILD; PRESCRIPTION; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ADRENERGIC AGONISTS; ADULT; AGED; ANAPHYLAXIS; ANIMALS; BLOOD PRESSURE; CHILD; CHILD, PRESCHOOL; DOGS; EPINEPHRINE; FEMALE; FIRST AID; HUMANS; HYPERSENSITIVITY; INFANT; MALE; MIDDLE AGED; PRESCRIPTIONS, DRUG; PROSPECTIVE STUDIES; RANDOMIZED CONTROLLED TRIALS; SELF ADMINISTRATION;

EID: 2342574205     PISSN: 15282511     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (34)

1. American Academy of Allergy Asthma and Immunology (AAAAI) Board of Directors 1998 Anaphylaxis in schools and other child-care settings. J Allergy Clin Immunol 102:173-176
2. Austen KF 1974 Systemic anaphylaxis in the human being. N Engl J Med 291:661-664
3. Bautista E, Simons FER, Simons KJ et al 2002 Epinephrine fails to hasten hemodynamic recovery in fully-developed anaphylactic shock. Int Arch Allergy Immunol 128:151-164
4. Bock SA, Muñoz-Furlong A, Sampson HA 2001 Fatalities due to anaphylactic reactions to foods. J Allergy Clin Immunol 107:191-193
5. Chowdhury BA, Meyer RJ 2002 Intramuscular versus subcutaneous injection of epinephrine in the treatment of anaphylaxis. J Allergy Clin Immunol 109:720-721
6. Ewan PW, Clark AT 2001 Long-term prospective observational study of patients with peanut and nut allergy after participation in a management plan. Lancet 357:111-115
7. Gold MS, Sainsbury R 2000 First aid anaphylaxis management in children who were prescribed an epinephrine autoinjector device (EpiPen). J Allergy Clin Immunol 106:171-176
8. Grouhi M, Alshehri M, Hummel D, Roifman CM 1999 Anaphylaxis and epinephrine autoinjector training: who will teach the teachers? J Allergy Clin Immunol 104:190-193
9. Gu X, Simons FER, Simons KJ 1999 Epinephrine absorption after different routes of administration in an animal model. Biopharm Drug Dispos 20:401-405
10. Gu X, Simons KJ, Simons FER 2002 Is epinephrine administration by sublingual tablet feasible for the first-aid treatment of anaphylaxis? A proof-of-concept study. Biopharm Drug Dispos 23:213-216
11. Hoffman BB 2001 Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists. In: Hardman JG, Limbird LE, Gilman AG (eds) Goodman and Gilman's the pharmacological basis of therapeutics. 10th edn, McGraw-Hill Companies Inc, New York, p 215-268
12. Huang SW 1998 A survey of EpiPen use in patients with a history of anaphylaxis. J Allergy Clin Immunol 102:525-526
13. Luciuk GH 1993 Adrenalin anaphylaxis. J Allergy Clin Immunol 91:153
14. Physicians' Desk Reference. 2003. Medical Economics Co. Inc, Montvale, NJ, available from http://www.pdr.net
15. Pumphrey RSH 2000 Lessons for management of anaphylaxis from a study of fatal reactions. Clin Exp Allergy 30:1144-1150
16. Sampson HA, Mendelson L, Rosen JP 1992 Fatal and near-fatal anaphylactic reactions to food in children and adolescents. N Engl J Med 327:380-384
17. Shekelle PG, Woolf SH, Eccles M, Grimshaw J 1999 Clinical guidelines: developing guidelines. Br Med J 318:593-596
18. Sicherer SH, Forman JA, Noone SA 2000 Use assessment of self-administered epinephrine among food-allergic children and pediatricians. Pediatrics 105:359-362
19. Simons FER, Roberts JR, Gu X, Simons KJ 1998 Epinephrine absorption in children with a history of anaphylaxis. J Allergy Clin Immunol 101:33-37
20. Simons FER, Gu X, Johnston L, Simons KJ 2000a Can epinephrine inhalations be substituted for epinephrine injection in children at risk for systemic anaphylaxis? Pediatrics 106:1040-1044
21. Simons FER, Gu X, Simons KJ 2000b Outdated EpiPen and EpiPen Jr auto-injectors: past their prime? J Allergy Clin Immunol 105:1025-1030
22. Simons FER, Peterson S, Black CD 2001a Epinephrine dispensing for the out-of-hospital treatment of anaphylaxis in infants and children: a population-based study. Ann Allergy Asthma Immunol 86:622-626
23. Simons FER, Chan ES, Gu X, Simons KJ 2001b Epinephrine for the out-of-hospital (first aid) treatment of anaphylaxis in infants: is the ampule/syringe/needle method practical? J Allergy Clin Immunol 108:1040-1044
24. Simons FER, Gu X, Simons KJ 2001c Epinephrine absorption in adults: intramuscular versus subcutaneous injection. J Allergy Clin Immunol 108:871-873
25. Simons FER, Peterson S, Black CD 2002a Epinephrine dispensing patterns for an out-ofhospital population: a novel approach to studying the epidemiology of anaphylaxis. J Allergy Clin Immunol 110:647-651
26. Simons FER, Gu X, Silver NA, Simons KJ 2002b EpiPen Jr versus EpiPen in young children weighing 15-30 kg at risk for anaphylaxis. J Allergy Clin Immunol 109:171-175
27. Simons FER, Gu X, Simons KJ 2002c Intramuscular versus subcutaneous injection of epinephrine in the treatment of anaphylaxis (correspondence). J Allergy Clin Immunol 109:720-721
28. Simons FER, Chad ZH, Gold M 2003 Anaphylaxis in children: real-time reporting from a national network. Int Immunol 15, in press
29. Smith PL, Kagey-Sobotka A, Bleecker ER et al 1980 Physiologic manifestations of human anaphylaxis. J Clin Invest 66:1072-1080
30. Toogood JH 1988 Risk of anaphylaxis in patients receiving beta-blocker drugs. J Allergy Clin Immunol 81:1-5
31. Watson A 1998 Alpha adrenergic blockers and adrenaline. A mysterious collapse. Aust Fam Physician 27:714-715
32. Yocum MW, Khan DA 1994 Assessment of patients who have experienced anaphylaxis: a 3-year survey. Mayo Clin Proc 69:16-23
33. Yocum MW, Butterfield JH, Klein JS, Volcheck GW, Schroeder DR, Silverstein MD 1999 Epidemiology of anaphylaxis in Olmsted County: a population-based study. J Allergy Clin Immunol 104:452-456
34. Yunginger JW, Sweeney KG, Sturner WQ et al 1988 Fatal food-induced anaphylaxis. J Am Med Assoc 260:1450-1452