Biochemical markers of bone metabolism and calciuria with inhaled budesonide therapy

Pediatric Nephrology

Volumn 19, Issue 5, 2004, Pages 511-515

  Akil, Ipek ^a,b   Yüksel, Hasan ^a   Ürk, Vildan ^a   Var, Ahmet ^a   Onur, Ece ^a  

^a CELAL BAYAR UNIVERSITY   (Turkey)

^b NONE   (Turkey)

Author keywords

Asthma; Bone metabolism; Calciuria; Inhaled budesonide; Natriuria

Indexed keywords

ALKALINE PHOSPHATASE; BIOCHEMICAL MARKER; BUDESONIDE; CALCIUM; CARBOXY TERMINAL TELOPEPTIDE; CORTICOSTEROID; ELECTROLYTE; GLUCOCORTICOID; OSTEOCALCIN; PARATHYROID HORMONE; PHOSPHATE; POTASSIUM; SODIUM;

ADOLESCENT; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; ASTHMA; BONE METABOLISM; CALCIUM ABSORPTION; CALCIUM BLOOD LEVEL; CALCIUM EXCRETION; CALCIUM URINE LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ELECTROLYTE BLOOD LEVEL; FEMALE; HUMAN; HYPOCALCIURIA; INTESTINE ABSORPTION; MALE; OSTEOLYSIS; PHOSPHATE BLOOD LEVEL; POTASSIUM BLOOD LEVEL; POTASSIUM EXCRETION; PRIORITY JOURNAL; SCHOOL CHILD; SIDE EFFECT; SODIUM BLOOD LEVEL; SODIUM EXCRETION; STATISTICAL ANALYSIS; URINARY EXCRETION;

ADMINISTRATION, INHALATION; ALKALINE PHOSPHATASE; ASTHMA; BIOLOGICAL MARKERS; BONE AND BONES; BRONCHODILATOR AGENTS; BUDESONIDE; CALCIUM; CHILD; COLLAGEN TYPE I; FEMALE; HUMANS; MALE; PARATHYROID HORMONE; POTASSIUM; SODIUM;

EID: 2342572844     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-004-1418-z     Document Type: Article

References (23)

1. Saravi FD, Guirao MA, Elias PC, Guarnieri PJ (2000) Influence of inhaled glucocorticoids on bone mineral density and bone metabolism (in Spanish). Rev Panam Salud Publica 7:211-218
2. Pedersen S (2002) Long-term outcomes in paediatric asthma. Allergy 57 [Suppl 74]:58-74
3. Valeri PM, Gomez EM, Valeri E, Salinas R, Bellabarba GA (2000) Effect of budesonide on bone density and metabolism in asthmatic children (in Spanish). Salud Publica Mex 42:309-314
4. Allen DB (2002) Inhaled corticosteroid therapy for asthma in preschool children: growth issues. Pediatrics 109:373-380
5. Delacourt C, Dutau G, Lefrancois G, Clerson P (2003) Comparison of the efficacy and safety of nebulized beclometasone dipropionate and budesonide in severe persistent childhood asthma. Respir Med 97 [Suppl B]:S27-S33
6. Kannisto S, Korppi M, Arikoski P, Remes K, Voutilainen R (2002) Biochemical markers of bone metabolism in relation to adrenocortical and growth suppression during the initiation phase of inhaled steroid therapy. Pediatr Res 52:258-262
7. (2002) Global strategy for asthma management and prevention (revised form). National Institute of Health, Bethesda, USA'
8. Rao R, Gregson RK, Jones AC, Miles EA, Campbell MJ, Warner JO (1999) Systemic effects of inhaled corticosteroids on growth and bone turnover in childhood asthma: a comparison of fluticasone with beclamethasone. Eur Respir J 13:87-94
9. Allen HD, Thong IG, Clifton-Bligh P, Holmes S, Nery L, Wilson KB (2000) Effects of high-dose inhaled corticosteroids on bone metabolism in prepubertal children with asthma. Pediatr Pulmonol 29:188-193
10. Bootsma P, Dekhuijzen RD, Festen J, Mulder PGH, Swinkels MJW, Herwaarden CLA van (1996) Fluticasone propionate does not influence bone metabolism in contrast to beclomethasone dipropionate. Am J Respir Crit Care 153:924-930
11. Pauwels RA, Yernault JC, Demedts MG, Geusens P (1998) Safety and efficacy of fluticasone and beclomethasone in moderate to severe asthma. Am J Respir Crit Care Med 157:827-832
12. Ali NJ, Capewell S, Ward MJ (1991) Bone turnover during high dose inhaled corticosteroid treatment. Thorax 46:160-164
13. Boulet LP, Milot J, Gagnon L, Poubellee PE, Brown J (1999) Long-term influence of inhaled corticosteroids on bone metabolism and density. Are biological markers predictors of bone loss? Am J Crit Care Med 159:838-844
14. Bahceciler NN, Sezgin G, Nursoy MA, Barlan IB, Basaran MM (2002) Inhaled corticosteroids and bone density of children with asthma. J Asthma 39:151-157
15. König P, Hillman L, Cervantes C, Levine C, Maloney C, Douglass B, Johnson L, Allen S (1993) Bone metabolism in children with asthma treated with inhaled beclomethasone dipropionate. J Pediatr 122:219-226
16. Chay OM, Goh A, Lim WH, Leong KH, Lou J (1999) Effects of inhaled corticosteroid on bone turnover in children with bronchial asthma. Respirology 4:63-67
17. Agertoft L, Pedersen S (1998) Bone mineral density in children with asthma receiving long-term treatment with inhaled budesonide. Am J Respir Crit Care Med 157:178-183
18. Martinati LC, Sette L, Chiocca E, Zaninotto M, Plebani M, Boner AL (1993) Effect of beclomethasone dipropionate nasal aerosol on serum markers of bone metabolism in children with seasonal allergic rhinitis. Clin Exp Allergy 23:986-991
19. Harris M, Hauser S, Nguyen TV, Kelly PJ, Rodda C, Morton J, Freezer N, Strauss BJG, Eisman JA, Walker JL (2001) Bone mineral density in prepubertal asthmatics receiving corticosteroid treatment. J Paediatr Child Health 37:67-71
20. Toogood JH, Crilly RG, Jones G, Nadeau J, Wells GA (1988) Effect of high-dose inhaled budesonide on calcium and phosphate metabolism and the risk of osteoporosis. Am Rev Respir Dis 138:57-61
21. Portale AA (1999) Calcium and phosphorus. In: Barratt TM, Avner ED, Harmon WE (eds) Pediatric nephrology, 4th edn. Lippincott Williams and Wilkins, pp 191-213
22. Smith BJ, Phillips PJ, Pannall PR, Cain HJ, Leckie WJ (1993) Effect of orally administered beclomethasone dipropionate on calcium absorption from the gut in normal subjects. Thorax 48:890-893
23. Borghi L, Schianchi T, Meschi T, Guerra A, Allegri F, Maggiore U, Novarim A (2002) Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med 346:77-84