Soybean isoflavones inhibit estrogen-stimulated gene expression in mouse uteri

European Journal of Gynaecological Oncology

Volumn 25, Issue 3, 2004, Pages 311-314

  Lian, Z ^a   Niwa, K ^a   Gao, J ^a   Tagami, K ^a   Onczi, K ^a   Mori, H ^a   Tamaya, T ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

c fos jun; IL 1 , TNF ; Soybean isoflavones

Indexed keywords

DAIDZEIN; ESTRADIOL; ESTROGEN; GENISTEIN; GLYCOSIDE; INTERLEUKIN 1ALPHA; ISOFLAVONE; MESSENGER RNA; PROTEIN C JUN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GENE EXPRESSION; HORMONAL CARCINOGENESIS; MOUSE; NONHUMAN; ONCOGENE C FOS; OVARIECTOMY; PROTEIN EXPRESSION; SOYBEAN; UTERUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; DNA PRIMERS; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, FOS; GENES, JUN; GENISTEIN; INTERLEUKIN-1; ISOFLAVONES; MICE; MICE, INBRED ICR; PHYTOTHERAPY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SOYBEANS; TUMOR NECROSIS FACTOR-ALPHA; UTERINE NEOPLASMS; UTERUS;

EID: 2342559241     PISSN: 03922936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Lian Z., Niwa K., Takami K., Hashimoto M., Gao J., Yokoyama Y. et al.: "Preventive effects of isoflavones, genistein and daidzein, on estradiol-17β-related endometrial carcinogenesis in mice". Jpn. J. Cancer Res., 2001, 92, 726.
2. Onozawa M., Kawamori T., Baba M., Fukuda K., Toda T., Sato, H. et al.: "Effects of soybean isoflavone mixture on carcinogenesis in prostate and seminal vesicles of F344 rat". Jpn. J. Cancer Res., 1999, 90, 393.
3. Wei H., Browen R., Zhang X., Lebwohl M. et al.: "Isoflavone genistein inhibits the initiation and promotion of two-stage skin carcinogenesis in mice". Carcinogenesis, 1998, 19, 1509.
4. Hsieh C. Y., Santell R. C., Haslam S. Z., Helferich W. G. et al.: "Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo". Cancer Res., 1998, 58, 3833.
5. Kato K., Takahashi S., Cui L., Toda T., Suzuki S., Futakuchi M. et al.: "Suppressive effects of dietary genistin and daidzin on rat prostate carcinogenesis". Jpn. J. Cancer Res., 2000, 91, 786.
6. Fukutake M., Takahashi M., Ishida K., Kawamura H., Sugimura T., Wakabayashi K. et al.: "Quantification of genistein and genistin in soybeans and soybean products". Food Chem. Toxicol., 1996, 34, 457.
7. Giri A. K., Lu L-J, W.: "Genetic damage and the inhibition of 7, 12-dimethylbenz [a] anthracene-induced genetic damage by the phytoestrogens, genistein and daidzein, in female ICR mice". Cancer Lett., 1995, 95, 125.
8. Chomczynski P., Sacchi N. et al.: "Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction". Anal. Biochem., 1987, 162, 156.
9. Weitz A., Bresciani F.: "Estrogen induces expression of c-fos and c-myc protooncogenes in the rat uterus". Mol. Endocrionol., 1988, 2, 816.
10. Weatz A., Cicatiello L., Persiot E., Scalona M., Bresciani F. et al.: "Estrogen stimulation of transcription of c-jun protooncogene". Mol. Endocrionol., 1990, 4, 1031.
11. Lomedico P.T., Gubler U., Hellmann C.P., Dukovich M., Giri J. G., Pan Y.C. et al.: "Cloning and expression murine interleukin-1 cDNA in Escherichia coli". Nature, 1984, 312, 458.
12. Fransen L., Muller R., Marmenout A., Tavernier J., Van der Heyden J., Kawashima E. et al.: "Molecular cloning of mouse tumor necrosis factor cDNA and its eukaryotic expression". Nucl. Aci. Res., 1985, 13, 417.
13. Sabath D., Broome H.E., Prystowsky M.B.: "mRNA is a major interleukin 2-induced transcript in a cloned T-helper lymphocyte". Gene, 1990, 91, 185.
14. Niwa K., Hashimoto M., Morishita S., Lian Z., Tagami K., Mori H.: "Preventive effects of Juzen-taiho-to on N-methyl-N-nitrosourea and estradiol-17β-induced endometrial carcinogenesis in mice". Carcinogenesis, 2001, 22, 587.
15. Niwa K., Murase T., Furui T., Morishita S., Tanaka T., Mori H. et al.: "Enhancing effects of estrogens on endometrial carcinogenesis initiated by N-methyl-N-nitrosourea in ICR mice". Jpn. J. Cancer Res., 1993, 84, 951.
16. Morishita S., Niwa K., Ichigo S., Hori M., Murase T. Fujimoto J. et al.: "Overexpressions of c-fos/jun mRNA and their oncoproteins (Fos/Jun) in the mouse uterus treated with three natural estrogens". Cancer Lett., 1995, 97, 225.
17. Lian Z., Niwa K., Gao J., Tagami K., Hashimoto M., Yokoyama Y. et al.: "Shimotsu-to is the agent in Juzen-taiho-to responsible for the prevention of endometrial carcinogenesis in mice". Cancer Lett., 2002, 182, 19.
18. Castrilli G., Tatone D., Diodoro M.G., Rosini S., Piantelli M., Musiani P. et al.: "Interleukin 1 alpha and interleukin 6 promote the in vitro growth of both normal and neoplastic human cervical epithelial cells". Brit. J. Cancer, 1997, 75, 855.
19. Suganuma M., Okabe S., Marino M.W., Sakai A., Sueoka E., Fujiki H. et al.: "Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice". Cancer Res., 1999, 59, 4516.
20. Fujiki H., Suganuma M., Okabe S., Sueoka E., Suga K., Imai K. et al.: "A new concept of tumor promotion by tumor necrosis factor-alpha, and cancer preventive agents (-)-epigallocatechin gallate and green tea - a review". Cancer Dete. Preven., 2000, 24, 91.
21. Suganuma M., Okabe S., Sueoka E., Iida N., Komori A., Kim S. J. et al.: "A new process of cancer prevention mediated through inhibition of tumor necrosis factor expression". Cancer Res., 1996, 56, 3711.
22. Hur H.G., Lay J.O. Jr, Beger R.D., Freeman J.P., Rafii F. et al.: "Isolation of human intestinal bacteria metabolizing the natural isoflavone glycosides daidzin and genistin". Arch Microbiol., 2000, 174, 422.