Selective COX-2 inhibitor, NS-398, inhibits the replicative senescence of cultured dermal fibroblasts

Mechanisms of Ageing and Development

Volumn 125, Issue 5, 2004, Pages 359-366

  Han, Ji Hyun ^a   Roh, Min Soo ^b   Park, Chi Hyun ^a   Park, Kyung Chan ^a   Cho, Kwang Hyun ^a   Kim, Kyu Han ^a   Eun, Hee Chul ^a   Chung, Jin Ho ^a  

^a Seoul National University Hospital   (South Korea)

^b AmorePacific Corporation   (South Korea)

Author keywords

COX 2; NS 398; PGE2; Replicative senescence

Indexed keywords

CELL CYCLE PROTEIN; CYCLINE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; INTERSTITIAL COLLAGENASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROCOLLAGEN; PROSTAGLANDIN E2; PROTEIN P53; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

AGING; ARTICLE; CELL AGING; CELL CYCLE; CELL GROWTH; CELL PROLIFERATION; CELLULAR DISTRIBUTION; COLLAGEN DISEASE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; EXPERIMENTAL MODEL; FIBROBLAST; GROWTH INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SKIN CELL;

ARTHRITIS, RHEUMATOID; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; FIBROBLASTS; HUMANS; ISOENZYMES; MALE; MATRIX METALLOPROTEINASE 1; MEMBRANE PROTEINS; NEOPLASMS; NITROBENZENES; PROLIFERATING CELL NUCLEAR ANTIGEN; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SKIN; SULFONAMIDES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 2342557049     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2004.02.002     Document Type: Article

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