Antioxidant status in acute stroke patients and patients at stroke risk

European Neurology

Volumn 51, Issue 3, 2004, Pages 157-161

  Zimmermann, C ^a   Winnefeld, K ^b   Streck, S ^b   Roskos, M ^b   Haberl, R L ^a,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c Krankenhaus Munich Harlaching   (Germany)

Author keywords

Acute stroke; Antioxidants; Glutathione; Glutathione peroxidase; Stroke risk; Superoxide dismutase

Indexed keywords

ANTIOXIDANT; COPPER; ENZYME; GLUTATHIONE; GLUTATHIONE PEROXIDASE; IRON; MALONALDEHYDE; MINERAL; SELENIUM; SUPEROXIDE DISMUTASE; ZINC;

ACUTE DISEASE; ADULT; AGED; ANAMNESIS; ARTERIOSCLEROSIS; ARTICLE; BRAIN INFARCTION; BRAIN ISCHEMIA; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME ANALYSIS; FEMALE; HOSPITAL ADMISSION; HUMAN; MALE; MEASUREMENT; PATIENT; PRIORITY JOURNAL; RISK ASSESSMENT; SCORING SYSTEM; STROKE; TIME;

AGED; ANTIOXIDANTS; CASE-CONTROL STUDIES; CEREBROVASCULAR ACCIDENT; FEMALE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HUMANS; MALE; MALONDIALDEHYDE; MIDDLE AGED; MINERALS; NEUROLOGIC EXAMINATION; REFERENCE VALUES; RISK; SELENIUM; SEVERITY OF ILLNESS INDEX; SPECTROMETRY, FLUORESCENCE; STATISTICS; STATISTICS, NONPARAMETRIC; SUPEROXIDE DISMUTASE; TIME FACTORS;

EID: 2342540913     PISSN: 00143022     EISSN: None     Source Type: Journal    
DOI: 10.1159/000077662     Document Type: Article

References (26)

1. Carden DL, Granger DN: Pathophysiology of ischaemia-reperfusion injury. J Pathol 2000;190:255-266.
2. Chan PH: Role of oxidants in ischemic brain damage. Stroke 1996;27:1124-1129.
3. El Kossi MM, Zakhary MM: Oxidative stress in the context of acute cerebrovascular stroke. Stroke 2000;31:1889-1892.
4. Leinonen JS, Ahonen JP, Lonnrot K, Jehkonen M, Dastidar P, Molnar G, Alho H: Low plasma antioxidant activity is associated with high lesion volume and neurological impairment in stroke. Stroke 2000;31:33-39.
5. Spranger M, Krempien S, Schwab S, Donneberg S, Hacke W: Superoxide dismutase activity in serum of patients with acute cerebral ischemic injury. Correlation with clinical course and infarct size. Stroke 1997;28:2425-2428.
6. Goldstein LB, Samsa GP: Reliability of the National Institutes of Health Stroke Scale. Extension to non-neurologists in the context of a clinical trial. Stroke 1997;28:307-310.
7. Truelsen T, Lindenstrom E, Boysen G: Comparison of probability of stroke between the Copenhagen City Heart Study and the Framingham Study. Stroke 1994;25:802-807.
8. Paglia DE, Valentine WN: Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158-169.
9. Yagi K: Lipid peroxides and human diseases. Chem Phys Lipids 1987;45:337-351.
10. Mergel D, Andermann G, Andermann C: Simultaneous spectrophotometric determination of oxidized and reduced glutathione in human and rabbit red cells. Methods Find Exp Clin Pharmacol 1979;1:277-283.
11. Winnefeld K, Streck S, Treff E, Jutte H, Kroll E, Marx H: Reference ranges of antioxidant parameters in whole blood (erythrocytes) in a Thuringa region. Med Klin 1999;94(suppl 3):101-102.
12. Chang CY, Lai YC, Cheng TJ, Lau MT, Hu ML: Plasma levels of antioxidant vitamins, selenium, total sulfhydryl groups and oxidative products in ischemic-stroke patients as compared to matched controls in Taiwan. Free Radic Res 1998;28:15-24.
13. Demirkaya S, Topcuoglu MA, Aydin A, Ulas UH, Isimer AI, Vural O: Malondialdehyde, glutathione peroxidase and superoxide dismutase in peripheral blood erythrocytes of patients with acute cerebral ischemia. Eur J Neurol 2001;8:43-51.
14. Sharpe PC, Mulholland C, Trinick T: Ascorbate and malondialdehyde in stroke patients. Ir J Med Sci 1994;163:488-491.
15. Schulz JB, Lindenau J, Seyfried J, Dichgans J: Glutathione, oxidative stress and neurodegeneration. Eur J Biochem 2000;267:4904-4911.
16. Bains JS, Shaw CA: Neurodegenerative disorders in humans: The role of glutathione in oxidative stress-mediated neuronal death. Brain Res Brain Res Rev 1997, 25:335-358.
17. Chang ML, Klaidman LK, Adams JD: The effects of oxidative stress on in vivo brain GSH turnover in young and mature mice. Mol Chem Neuropathol 1997;30:187-197.
18. Cherubini A, Polidori MC, Bregnocchi M, Pezzuto S, Cecchetti R, Ingegni T, di Iorio A, Senin U, Mecocci P: Antioxidant profile and early outcome in stroke patients. Stroke 2000;31:2295-2300.
19. Kocaturk PA, Akbostanci MC, Isikay C, Ocal A, Tuncel D, Kavas GO, Mutluer N: Antioxidant status in cerebrovascular accident. Biol Trace Elem Res 2001;80:115-124.
20. Zachara BA, Ukleja-Adamowicz M, Nartowicz E, Lecka J: Increased plasma glutathione peroxidase activity in patients with acute myocardial infarction. Med Sci Monit 2001;7:415-420.
21. Takizawa S, Matsushima K, Shinohara Y, Ogawa S, Komatsu N, Utsunomiya H, Watanabe KJ: Immunohistochemical localization of glutathione peroxidase in infarcted human brain. Neurol Sci 1994;122:66-73.
22. Avissar N, Whitin JC, Allen PZ, Wagner DD, Liegey P, Cohen HJ: Plasma selenium-dependent glutathione peroxidase. Cell of origin and secretion. J Biol Chem 1989;264:15850-15855.
23. Murakami T, Takemori K, Takeda T, Yoshizumi H: Relationship between erythrocytes glutathione peroxidase and incidence of stroke lesion in the stroke-prone spontaneously hypertensive rat. Clin Exp Pharmacol Physiol Suppl 1995;1:S162-164.
24. Weisbrot-Lefkowitz M, Reuhl K, Perry B, Chan PH, Inouye M, Mirochnitchenko O: Overexpression of human glutathione peroxidase protects transgenic mice against focal cerebral ischemia/reperfusion damage. Brain Res Mol Brain Res 1998;53:333-338.
25. Maehira F, Luyo GA, Miyagi I, Oshiro M, Yamane N, Kuba M, Nakazato Y: Alterations of serum selenium concentrations in the acute phase of pathological conditions. Clin Chim Acta 2002;316:137-146.
26. Bor MV, Cevik C, Uslu I, Guneral F, Duzgun E: Selenium levels and glutathione peroxidase activities in patients with acute myocardial infarction. Acta Cardiol 1999;54:271-276.