Effects of 3,4-methylenedioxymethamphetamine ('Ecstasy') on the jaw-opening reflex and on the α2-adrenoceptors which regulate this reflex in the anesthetized rat

European Journal of Oral Sciences

Volumn 112, Issue 2, 2004, Pages 127-133

  Arrue, Aurora ^a   Gómez, Francisco M ^a   Giralt, M Teresa ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

2 adrenoceptors; 3, 4 methylenedioxymethamphetamine; Bruxism; Jaw opening reflex; Rat

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; ADRENERGIC RECEPTOR AFFECTING AGENT;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRUXISM; DRUG USE; ELECTROMYOGRAM; ELECTROSTIMULATION; JAW OPENING REFLEX; MALE; NONHUMAN; NORADRENERGIC SYSTEM; RAT; RECEPTOR SENSITIVITY; ANIMAL; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ELECTROMYOGRAPHY; EVOKED MUSCLE RESPONSE; INTRAVENOUS DRUG ADMINISTRATION; MANDIBLE; NECK MUSCLE; REFLEX; SPRAGUE DAWLEY RAT;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC UPTAKE INHIBITORS; ANIMALS; BRUXISM; CLONIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; EVOKED POTENTIALS, MOTOR; INJECTIONS, INTRAVENOUS; MALE; MANDIBLE; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; NECK MUSCLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; REFLEX;

EID: 2342535012     PISSN: 09098836     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0722.2004.00114.x     Document Type: Article

References (49)

1. PEROUTKA SJ, NEWMAN H, HARRIS H. Subjective effects of 3, 4-methylenedioxymethamphetamine in recreational users. Neuropsychopharmacol 1988; 1: 273-277.
2. VOLLENWEIDER FX, GAMMA A, LIETCHTI M, HUBER T. Psychological and cardiovascular effects and short-term sequelae of MDMA ('Ecstasy') in MDMA-näive healthy volunteers. Neuropsychopharmacol 1998; 19: 241-251.
3. SOLOWIJ N, HALL W, LEE N. Recreational MDMA use in Sidney: a profile of 'Ecstasy' users and their experience with the drug. Br J Addiction 1992; 87: 1161-1172.
4. MILOSEVIC A, AGRAWAL N, REDFEARN PJ, MAIR LH. The occurrence of toothwear in users of Ecstasy (3,4-methylenedioxymethamphetamine). Community Dent Oral Epidemiol 1999; 27: 283-287.
5. WINOCUR E, GAVISH A, VOLFIN G, HALACHMI M, GAZIT E. Oral motor parafunctions among heavy drug addicts and their effects on signs and symptoms of temporomandibular disorders. J Orofacial Pain 2001; 15: 56-63.
6. SPRAGUE JE, EVERMAN SL, NICHOLS DE. An integrated hypothesis for the serotonergic axonal loss induced by 3, 4-methylenedioxymethamphetamine. Neurotoxicology 1998; 19: 427-442.
7. ROTHMAN RB, BAUMAN MH, DERSH CM, ROMERO DV, RICE KC, CARRO FI, PARTILLA JS. Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse 2001; 39: 32-41.
8. 3H]paroxetine-labeled serotonin uptake sites. J Pharmacol Exp Ther 1987; 242: 911-916.
9. COMMINS DE, VOSMER G, VIRUS RM, WOOLVERTON WL, SCHUSTER CR, SEIDEN LS. Biochemical and histological evidence that MDMA is toxic to neurons in the rat brain. J Pharmacol Exp Ther 1987; 241: 338-345.
10. LOBBEZOO F, NAEIJE M. Bruxism is mainly regulated centrally, not peripherally. J Oral Rehab 2001; 28: 1085-1091.
11. WINOCUR E, GAVISH A, VOIKOVITCH M, EMODI-PERLMAN A, ELI I. Drugs and bruxism: a critical review. J Orofacial Pain 2003; 17: 99-110.
12. LAVIGNE G, MONTPLAISIR JV. Epidemiology, diagnosis, pathophysiology and pharmacology. In: FRICTON, JR, DUBNER, R, eds. Orofacial pain and temporomandibular disorders. New York, NY: Raven Press 1995, 387-404.
13. KATAKURA N, CHANDLER SH. An iontophoretic analysis of pharmacological mechanisms responsible for trigeminal motoneuronal discharge during masticatory-like activity in the guinea pig. J Neurophysiol 1990; 63: 356-369.
14. HSIAO CF, TRUEBLOOD PR, LEVINE MS, CHANDLER SH. Multiple affects of serotonin on membrane properties of trigeminal motoneurons in vitro. J Neurophysiol 1997; 77: 2910-2924.
15. KURASAWA I, TODA K, NAKAMURA Y. Non-reciprocal facilitation of trigeminal motoneurons innervating jaw-closing and jaw-opening muscles induced by iontophoretic application of serotonin in the guinea pig. Brain Res 1990; 515: 126-134.
16. NAGASE Y, MORITANI M, NAKAGAWA S, YOSHIDA A, TAKEMURA M, ZHANG LF, KIDA H, SHIGENAGA Y. Serotonergic axonal contacts on identified cat trigeminal motoneurons and their correlation with medullary raphe nucleus stimulation. J Comp Neurol 1997; 384: 443-455.
17. RIBEIRO DO, VALLE LE, METZLER CW, JACOBS BL. Facilitation of masseter EMG and masseteric (jaw-closure) reflex by serotonin in behaving cats. Brain Res 1991; 550: 197-204.
18. STAFFORD IL, JACOBS BL. Noradrenergic modulation of the masseteric reflex in behaving cats. I. Pharmacological studies. J Neurosci 1990; 10: 91-98.
19. SESSLE BJ, HU JW. Raphe-induced suppression of the jaw-opening reflex and single neurons in trigeminal subnucleus oralis, and influence of naloxone and subnucleus caudalis. Pain 1981; 10: 19-36.
20. HAMBA M, TODA K. Rat hypothalamic arcuate neuron response in electroacupuncture-induced analgesia. Brain Res Bull 1988; 21: 31-35.
21. KATAKURA N, CHANDLER SH. Iontophoretic analysis of the pharmacological mechanisms responsible for initiation and modulation of trigeminal motoneuronal discharge evoked by intra-oral afferent stimulation. Brain Res 1991; 549: 66-77.
22. 2-adrenoceptors of the jaw-opening reflex induced by orofacial stimulation in rats. Br J Pharmacol 1994; 111: 1140-1146.
23. LUND JP, OLSSON KA. The importance of reflexes and their control during jaw movement. Trends Neurosci 1983; 6: 458-463.
24. LINDQVIST B, HEIJBEL J. Bruxism in children with brain damage. Acta Odontol Scand 1974; 32: 313-319.
25. WARE JC, RUGH JD. Destructive bruxism: sleep stage relationship. Sleep 1988; 11: 172-181.
26. INOUE M, YAMAMURA K, NAKAJIMA T, YAMADA Y. Changes in reflex response of the masseter and digastric muscles during sleep in freely behaving rabbits. Neurosci Res 1999; 34: 37-44.
27. LANDGREN S, OLSSON KA. The effect of electrical stimulation in the hypothalamus on the monosynaptic jaw closing and the disynaptic jaw opening reflexes in the cat. Exp Brain Res 1980; 39: 389-400.
28. INOUE M, NOZAWA-INOUE K, MIYAOKA Y, YAMADA Y. Changes in jaw reflexes by stimulation of the hypothalamus in anesthetized rabbits. Neurosci Res 2001; 41: 61-65.
29. DE LAAT A, SVENSSON P, MACALUSO GM. Are jaw and facial reflexes modulated during clinical or experimental orofacial pain? J Orofac Pain 1998; 12: 260-271.
30. DE LAAT A, VAN DER GLAS HW, WEYTJENS JLF, VAN STEENBERGHE D. The masseteric post-stimulus electromyographic-complex in people with dysfunction of the mandibular joint. Arch Oral Biol 1985; 30: 177-180.
31. SHARAV Y, MCGRATH PA, DUBNER R. Masseter inhibitory periods and sensations by electrical pulp stimulation in patients with oral-facial pain and mandibular dysfunction. Arch Oral Biol 1982; 27: 305-310.
32. PARKER RB, WAUD DR. Pharmacological estimation of drug-receptor dissociation constants. Statistical evaluation. I. Agonist. J Pharmacol Exp Ther 1971; 177: 1-12.
33. 2-adrenoceptors which modulate the jaw-opening reflex in the rat. Brain Res 1998; 801: 72-77.
34. 2- adrenoceptors which modulate the jaw-opening reflex in the rat. Psychopharmacology 1998; 138: 96-101.
35. 1B/1D receptor agonist on spinal and trigeminal reflexes in the anaesthetized rabbit. Br J Pharmacol 2000; 131: 974-980.
36. SEO K, FUJIWARA N, HU JW, CAIRNS BE, SOMEYA G. Intrathecal administration of 5-HT3 receptor agonist modulates jaw muscle activity evoked by injection of mustard oil into the temporomandibular joint in the rat. Brain Res 2002; 934: 157-161.
37. CHANDLER SH, GOLDBERG LJ, ALBA B. Effects of a serotonin agonist and antagonist on cortically induced rhythmical jaw movements in the anesthetized guinea pig. Brain Res 1985; 334: 201-206.
38. CADDEN SW. The digastric reflex evoked by tooth pulp stimulation in the cat and its modulation by stimuli applied to the limbs. Brain Res 1985; 336: 33-43.
39. STEINBUSCH HWM. Distribution of serotonin-immunoreactivity in the central nervous system of the rat. Cell bodies and terminals. Neuroscience 1981; 6: 557-618.
40. GRUDT TJ, WILLIAMS JT, TRAVAGLI RA. Inhibition by 5-hydroxytryptamine and noradrenaline in substantia gelatinosa of guinea-pig spinal trigeminal nucleus. J Physiol 1995; 485: 113-120.
41. SASA M, FUJIMOTO S, IGARASHI S, MUNEKIYO K, TAKAORI S. Microiontophoretic studies on noradrenergic inhibition from locus coeruleus of spinal trigeminal nucleus neurons. J Pharmacol Exp Ther 1979; 210: 311-315.
42. LAVELLE A, HONNER V, DOCHERTY JR. Investigation of the prejunctional alpha-2 adrenoceptor mediated actions of MDMA in rat atrium and vas deferens. Br J Pharmacol 1999; 128: 975-980.
43. CURTIS AL, MARWAH J. Evidence for alpha adrenoceptor modulation of the nociceptive jaw-opening in rats and rabbits. J Pharmacol Exp Ther 1986; 238: 576-579.
44. ARRUE A, RUIZ-ORTEGA JA, UGEDO L, GIRALT MT. Short-term effects of 3,4-methylenedioxymethamphetamine on noradrenergic activity in locus coeruleus and hippocampus of the rat. Neurosci Lett 2003; 337: 123-126.
45. NENCINI P, WOOLVERTON WL, SEIDEN LS. Enhancement of morphine-induced analgesia after repeated injections of methylenedioxymethamphetamine. Brain Res 1988; 457: 136-142.
46. HEAL DJ, PHILPOT J. A study of the possible influence of central 5-HT function on clonidine-induced hypoactivity responses in mice. Psychopharmacology 1987; 92: 219-223.
47. 1A receptors potentiates the clonidine inhibitory effect in the locus coeruleus. Eur J Pharmacol 1997; 333: 159-162.
48. SESSLE BJ. Acute and chronic craniofacial pain: Brainstem mechanisms of nociceptive transmission and neuroplasticity, and their clinical correlates. Crit Rev Oral Biol Med 2000; 11: 57-91.
49. STEPHENSON CP, HUNT GE, TOPPLE AN, MCGREGOR IS. The distribution of 3, 4-methylenedioxymethamphetamine 'Ecstasy'-induced c-fos expression in rat brain. Neuroscience 1999; 92: 1011-1023.