Angiotensin‐converting enzyme inhibition improves cardiac fatty acid metabolism in patients with congestive heart failure

Nuclear Medicine Communications

Volumn 24, Issue 8, 2003, Pages 901-906

  Yamauchi, S ^a   Takeishi, Y ^a   Minamihaba, O ^a   Arimoto, T ^a   Hirono, O ^a   Takahashi, H ^a   Miyamoto, T ^a   Nitobe, J ^a   Nozaki, N ^a   Tachibana, H ^a   Watanabe, T ^a   Fukui, A ^a   Kubota, I ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

Angiotensin converting enzyme inhibitor; Heart failure; I BMIPP; Metabolism.

Indexed keywords

DIAGNOSTIC AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; FATTY ACID; IODOBENZENE; IODOFILTIC ACID; RADIOPHARMACEUTICAL AGENT;

ARTICLE; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HEART; HEART MUSCLE; HUMAN; MALE; METABOLISM; MIDDLE AGED; SCINTISCANNING;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ENALAPRIL; FATTY ACIDS; FEMALE; HEART; HEART FAILURE, CONGESTIVE; HUMANS; IODOBENZENES; MALE; MIDDLE AGED; MYOCARDIUM; RADIOPHARMACEUTICALS;

EID: 2342507912     PISSN: 01433636     EISSN: 14735628     Source Type: Journal    
DOI: 10.1097/01.mnm.0000084579.51410.69     Document Type: Article

References (22)

1. McFate SW. Epidemiology of congestive heart failure. Am J Cardiol 1985; 55(suppl): 3A-8A.
2. Wagoner LE, Walsh RA. The cellular pathophysiology of progression to heart failure. Curr Opin Cardiol 1997; 11: 237-244.
3. Kataoka K, Nohara R, Hosokawa R, et al. Myocardial lipid metabolism in compensated and advanced stages of heart failure: evaluation by canine pacing model with BMIPP. J Nucl Med 2001; 42: 124-129.
4. The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). N Engl J Med 1987; 316: 1429-1435.
5. The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. N Engl J Med 1991; 325: 293-302.
6. 123I-BMIPP uptake in patients with congestive heart failure. J Nucl Med 2001; 42(suppl): 172P.
7. 123I-BMIPP imaging. Ann Nucl Med 1994; 8: 177-182.
8. Takeishi Y, Atsumi H, Fujiwara S, Takahashi K, Tomoike H. ACE inhibition reduces cardiac iodine-123-MIBG release in heart failure. J Nucl Med 1997; 38: 1085-1089.
9. Fujiwara S, Takeishi Y, Atsumi H, Takahashi K, Tomoike H. Fatty acid metabolic imaging with iodine-123-BMIPP for the diagnosis of coronary artery disease. J Nucl Med 1997; 38: 175-180.
10. Takeishi Y, Fujiwara S, Atsumi H, Takahashi K, Sukekawa K, Tomoike H. Iodine-123-BMIPP imaging in unstable angina: a guide for interventional strategy. J Nucl Med 1997; 38: 1407-1411.
11. 123I-15-(p-iodophenyl)-9-R,S-methylpentadecanoic acid in acute coronary syndrome. J Nucl Med 1999; 40: 1999-2006.
12. Jun T, Hirono O, Kubota I, et al. Dobutamine stress echocardiography for the diagnosis of myocardial viability. Jpn Heart J 2000; 41: 435-443.
13. Sack MN, Kelly DP. The energy substrate switch during development of heart failure: gene regulatory mechanisms. Int J Moll Med 1998; 1: 17-24.
14. Barger PM, Kelly DP. Fatty acid utilization in the hypertrophied and failing heart: molecular regulatory mechanism. Am J Med Sci 1999; 318: 36-42.
15. Sack MN, Rader TA, Park S, Bastin J, McCune SA, Kelly DP. Fatty acid oxidation enzyme gene expression is downregulated in the failing heart. Circulation 1996; 94: 2837-2842.
16. Depre C, Vanoverschelde JLJ, Taegtmeyer H. Glucose for the heart. Circulation 1999; 99: 578-588.
17. Recchia FA, McConnell PI, Bernstein RD, Vogel TR, Xu X, Hintze TH. Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog. Circ Res 1998; 83: 969-979.
18. Fukuzawa S, Ozawa S, Inagaki M, Sugioka J, Daimon M, Kushida S. Angiotensin-converting enzyme inhibitor therapy affects myocardial fatty acid metabolism after acute myocardial infarction. J Nucl Cardiol 2000; 7: 23-28.
19. Schoonderwoerd K, Broekhoven-Schkker S, Hulsmann WC, Stam H. Involvement of lysosome-like particles in the metabolism of endogenous myocardial triglycerides during ischemia/reperfusion. Uptake and degradation of triglycerides by lysosomes isolated from rat heart. Basic Res Cardiol 1990; 85: 153-163.
20. Schoonderwoerd K, Broekhoven-Schkker S, Hulsmann WC, Stam H. Enhanced lipolysis of myocardial triglycerides during low-flow ischemia and anoxia in the isolated rat heart. Basic Res Cardiol 1989; 84: 165-173.
21. Yamamichi Y, Kusuoka H, Morishita K, et al. Metabolism of iodine-123-BMIPP in perfused rat hearts. J Nucl Med 1995; 36: 1043-1050.
22. Paul K, Ball NA, Dorn GW, Walsh RA. Left ventricular stretch stimulates angiotensin II-mediated phosphatidylinositol hydrolysis and protein kinase C ε isoforms translocation in adult guinea pig hearts. Circ Res 1997; 81: 643-650.