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Volumn 34, Issue 3, 2004, Pages 159-161
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Phase I/II study of combination therapy of oral fluorinated pyrimidine compound S-1 with low-dose cisplatin in patients with unresectable and/or recurrent advanced gastric cancer: A novel study design to evaluate safety and efficacy
a
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Author keywords
Continual reassessment method; Gastric cancer; Low dose cisplatin; Phase I II trial; S 1
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Indexed keywords
5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR;
CISPLATIN;
ANTINEOPLASTIC AGENT;
OXONIC ACID;
PYRIDINE DERIVATIVE;
S 1 (COMBINATION);
TEGAFUR;
ADULT;
ADVANCED CANCER;
AGED;
ALOPECIA;
ARTICLE;
CANCER RECURRENCE;
CANCER SURVIVAL;
CLINICAL PROTOCOL;
CLINICAL TRIAL;
CONTROLLED CLINICAL TRIAL;
CONTROLLED STUDY;
DISEASE SEVERITY;
DRUG DOSE REGIMEN;
DRUG EFFICACY;
DRUG RESPONSE;
DRUG SAFETY;
FATIGUE;
FEBRILE NEUTROPENIA;
HUMAN;
LEUKOPENIA;
LOW DRUG DOSE;
MAJOR CLINICAL STUDY;
NAUSEA AND VOMITING;
NEUTROPENIA;
PATIENT SELECTION;
PHASE 1 CLINICAL TRIAL;
PHASE 2 CLINICAL TRIAL;
STATISTICAL ANALYSIS;
STATISTICAL SIGNIFICANCE;
STOMACH CANCER;
THROMBOCYTOPENIA;
AMBULATORY CARE;
CHEMICALLY INDUCED DISORDER;
DOSE RESPONSE;
DRUG ADMINISTRATION;
DRUG COMBINATION;
FEMALE;
MALE;
MIDDLE AGED;
MULTICENTER STUDY;
ORAL DRUG ADMINISTRATION;
STOMACH TUMOR;
TUMOR RECURRENCE;
ADMINISTRATION, ORAL;
ADULT;
AGED;
AMBULATORY CARE;
ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS;
CISPLATIN;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DRUG ADMINISTRATION SCHEDULE;
DRUG COMBINATIONS;
FEMALE;
HUMANS;
LEUKOPENIA;
MALE;
MIDDLE AGED;
NEOPLASM RECURRENCE, LOCAL;
NEUTROPENIA;
OXONIC ACID;
PYRIDINES;
STOMACH NEOPLASMS;
TEGAFUR;
THROMBOCYTOPENIA;
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EID: 2342503214
PISSN: 03682811
EISSN: 14653621
Source Type: Journal
DOI: 10.1093/jjco/hyh031 Document Type: Article |
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Times cited : (3)
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References (7)
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