Rapid, in vivo, evaluation of antiangiogenic and antineoplastic gene products by nonviral transfection of tumor cells

Cancer Gene Therapy

Volumn 11, Issue 5, 2004, Pages 346-353

  Weiss, Jonathan M ^a   Shivakumar, Rama ^a   Feller, Stephanie ^a   Li, Lin Hong ^a   Hanson, Art ^b   Fogler, William E ^b   Fratantoni, Joseph C ^a   Liu, Linda N ^a,c  

^a MAXCYTE INC   (United States)

^b ENTREMED INC   (United States)

^c NONE   (United States)

Author keywords

Anti angiogenesis; Anti tumor; Electroporation; Gene delivery; In vivo gene screening

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOSTATIN; ANTINEOPLASTIC AGENT; DNA; ENDOSTATIN; GENE PRODUCT; HYBRID PROTEIN; INTERLEUKIN 12; PLASMID DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RISK; CONTROLLED STUDY; CORRELATION ANALYSIS; ELECTROPORATION; EVALUATION; GENETIC IDENTIFICATION; GENETIC SCREENING; GENETIC TRANSFECTION; GROWTH INHIBITION; IMMUNOGENICITY; IN VIVO STUDY; KIDNEY CARCINOMA; LUNG METASTASIS; MELANOMA CELL; MOLECULAR CLONING; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN SECRETION; STATISTICAL SIGNIFICANCE; SURVIVAL RATE; VALIDATION PROCESS;

ANGIOSTATINS; ANIMALS; CARCINOMA, RENAL CELL; CELL DIVISION; CELL LINE, TUMOR; CLONING, MOLECULAR; ELECTROPORATION; ENDOSTATINS; EPSTEIN-BARR VIRUS NUCLEAR ANTIGENS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE THERAPY; GENETIC VECTORS; INTERLEUKIN-12; KIDNEY NEOPLASMS; LUNG NEOPLASMS; MALE; MELANOMA; MICE; MICE, INBRED BALB C; NEOVASCULARIZATION, PATHOLOGIC; RECOMBINANT FUSION PROTEINS; TRANSFECTION; VIRUSES;

ANIMALIA;

EID: 2342475274     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700686     Document Type: Article

References (28)

1. Dranoff G, Jaffee E, Lazenby A, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA. 1993;90:3539-3543.
2. Yannelli JR, Hyatt C, Johnson S, et al. Characterization of human tumor cell lines transduced with the cDNA encoding either tumor necrosis factor alpha (TNF-a) or interleukin-2 (IL-2). J Immunol Methods. 1993;161:77-90.
3. Feldman E, Ahmed T, Lutton JD, et al. Adenovirus mediated alpha interferon (IFN-alpha) gene transfer into CD34+ cells and CML mononuclear cells. Stem Cells. 1997;15:386-395.
4. Shiloni E, Karp SE, Custer MC, et al. Retroviral transduction of interferon-gamma cDNA into a nonimmunogenic murine fibrosarcoma: generation of T cells in draining lymph nodes capable of treating established parental metastatic tumor. Cancer Immunol Immunother. 1993;37: 286-292.
5. Nagai H, Hara I, Horikawa T, et al. Gene transfer of secreted-type modified interleukin-18 gene to B16F10 melanoma cells suppresses in vivo tumor growth through inhibition of tumor vessel formation. J Invest Dermatol. 2002;119:541-548.
6. Maehara N, Nagai E, Mizumoto K, et al. Gene transduction of NK4, HGF antagonist, inhibits in vitro invasion and in vivo growth of human pancreatic cancer. Clin Exp Metastasis. 2002;19:417-426.
7. Indraccolo S, Gola E, Rosato A, et al. Differential effects of angiostatin, endostatin and interferon-alpha(1) gene transfer on in vivo growth of human breast cancer cells. Gene Therapy. 2002;9:867-878.
8. Feldman AL, Alexander HR, Hewitt SM, et al. Effect of retroviral endostatin gene transfer on subcutaneous and intraperitoneal growth of murine tumors. J Natl Cancer Inst. 2001;93:1014-1020.
9. Scappaticci FA, Smith R, Pathak A, et al. Combination angiostatin and endostatin gene transfer induces synergistic antiangiogenic activity in vitro and antitumor efficacy in leukemia and solid tumors in mice. Mol Ther. 2001;3: 186-196.
10. Sauter BV, Martinet O, Zhang WJ, et al. Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases. Proc Natl Acad Sci USA. 2000;97: 4802-4807.
11. Scholz C, Starck L, Willimsky G, et al. Adenoviral transduction of tumor cells induces apoptosis in co-cultured T lymphocytes. Gene Therapy. 2002;9:1438-1446.
12. Steiner MS, Barrack ER. Transforming growth factor-beta 1 overproduction in prostate cancer: effects on growth in vivo and in vitro. Mol Endocrinol. 1992;6:15-25.
13. van Deventer HW, Serody JS, McKinnon KP, et al. Transfection of macrophage inflammatory protein 1 alpha into B16 F10 melanoma cells inhibits growth of pulmonary metastases but not subcutaneous tumors. J Immunol. 2002;169:1634-1639.
14. Klenchin VA, Sukharev SI, Serov SM, et al. Electrically induced DNA uptake by cells is a fast process involving DNA electrophoresis. Biophys J. 1991;60:804-811.
15. Wu H, Ceccarelli DF, Frappier L. The DNA segregation mechanism of Epstein-Barr virus nuclear antigen 1. EMBO Rep. 2000;1:140-144.
16. Cruickshank J, Shire K, Davidson AR, Edwards AM, Frappier L. Two domains of the Epstein-Barr virus origin DNA-binding protein, EBNA1, orchestrate sequence-specific DNA binding. J Biol Chem. 2000;275:22273-22277.
17. Li LH, Shivakumar R, Feller S, et al. Highly efficient, large volume flow electroporation. Technol Cancer Res Treat. 2002;1:341-350.
18. Iwai M, Harada Y, Ishii M, et al. Suicide gene therapy of human hepatoma and its peritonitis carcinomatosis by a vector of replicative-deficient herpes simplex virus. Biochem Biophys Res Commun. 2002;291:855-860.
19. Wilasrusmee C, Da Silva M, Singh B, et al. A new in vitro model to study endothelial injury. J Surg Res. 2002;104: 131-136.
20. Tomayko MM, Reynolds CP. Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemother Pharmacol. 1989;24:148-154.
21. Heller LC, Ingram SF, Lucas ML, et al. Effect of electrically mediated intratumor and intramuscular delivery of a plasmid encoding IFN alpha on visible B16 mouse melanomas. Technol Cancer Res Treat. 2002;1:205-209.
22. Rusciano D, Lorenzoni P, Burger M. Murine models of liver metastasis. Invas Metastasis. 1994;14:349-361.
23. Cichon T, Jamrozy L, Glogowska J, et al. Electrotransfer of gene encoding endostatin into normal and neoplastic mouse tissues: inhibition of primary tumor growth and metastatic spread. Cancer Gene Ther. 2002;9:771-777.
24. Cemazar M, Sersa G, Wilson J, et al. Effective gene transfer to solid tumors using different nonviral gene delivery techniques: electroporation, liposomes, and integrin-targeted vector. Cancer Gene Ther. 2002;9:399-406.
25. Sakurai F, Terada T, Maruyama M, et al. Therapeutic effect of intravenous delivery of lipoplexes containing the interferon-beta gene and poly I: poly C in a murine lung metastasis model. Cancer Gene Ther. 2003;10:661-668.
26. Chen ZY, He CY, Ehrhardt A, et al. Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. Mol Ther. 2003;8:495-500.
27. Li LH, Wang S, Wood M, et al. Non-viral gene transfer into resting primary lymphocytes: small and large volume. Mol Ther. 2001;3:S69.
28. Li LH, Feller S, Fratantoni JC, et al. Single base gene conversion by single strand DNA oligo delivered by electroporation. Mol Ther. 2002;5:S334.