Acidosis counteracts the negative inotropic effect of K+ on ventricular muscle strips from the toad Bufo marinus

Physiological and Biochemical Zoology

Volumn 77, Issue 2, 2004, Pages 223-231

  Andersen, Johnnie Bremholm ^a   Gesser, Hans ^a   Wang, Tobias ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; LACTATE SODIUM; LACTIC ACID; POTASSIUM; PYRUVIC ACID;

ECOPHYSIOLOGY;

ACIDOSIS; ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; COMPARATIVE STUDY; DRUG EFFECT; HEART CONTRACTION; IN VITRO STUDY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; TIME; TOAD;

ACIDOSIS; ANALYSIS OF VARIANCE; ANIMALS; BUFO MARINUS; EPINEPHRINE; LACTIC ACID; MYOCARDIAL CONTRACTION; POTASSIUM; PYRUVIC ACID; SODIUM LACTATE; TIME FACTORS;

ANIMALIA; ANURA; BUFO; BUFO MARINUS;

EID: 2342449223     PISSN: 15222152     EISSN: None     Source Type: Journal    
DOI: 10.1086/383501     Document Type: Article

References (32)

1. Andersen J.B. and T. Wang. 2003. Cardiorespiratory consequences of forced activity and digestion in toads. Physiol Biochem Zool 76:459-470.
2. Blake J. 1839. Observations on the physiological effects of various agents introduced into the circulation, as indicated by the haemadynamometer. Edinb Med Surg J 36:1-52.
3. Driedzic W.R. and H. Gesser. 1994. Energy metabolism and contractility in ectothermic vertebrate hearts: hypoxia, acidosis, and low temperature. Physiol Rev 74:221-258.
4. +-gelähmten Frosch: uns Säugetiermyokards durch Adrenalin. Pflug Arch 273:145-163.
5. Farrell A.P., K.R. MacLeod, and B. Chancey. 1986. Intrinsic mechanical properties of the perfused rainbow trout heart and the effects of catecholamines and extracellular calcium under control and acidotic conditions. J Exp Biol 125:319-345.
6. Farrell A.P., K.R. MacLeod, W.R. Driedzic, and S. Wood. 1983. Cardiac performance in the in situ perfused fish heart during extracellular acidosis: interactive effects of adrenaline. J Exp Biol 107:415-429.
7. Gesser H., P. Andresen, P. Brams, and J. Sund-Laursen. 1982. Inotropic effects of adrenaline on the anoxic or hypercapnic myocardium of rainbow trout and eel. J Comp Physiol B 147:123-128.
8. i, contractility and Ca-balance under hypercapnic acidosis in the myocardium of different vertebrate species. J Exp Biol 96:405-412.
9. Gesser H. and O. Poupa. 1975. Lactate as substrate for force development in hearts with different isoenzyme patterns of lactate dehydrogenase. Comp Biochem Physiol B 52:311-313.
10. 2+ under hypercapnic acidosis of cardiac muscle: comparative aspects. J Comp Physiol B 127:301-313.
11. _. 1983. Acidosis and cardiac muscle contractility: comparative aspects. Comp Biochem Physiol A 76:559-566.
12. Hedrick M.S., W.B. Palioca, and S.S. Hillman. 1999. Effects of temperature and physical activity on blood flow shunts and intracardiac mixing in the toad Bufo marinus. Physiol Biochem Zool 72:509-519.
13. 2+ in protecting the heart from hyperkalemia and acidosis in the rabbit: implications for exercise. J Appl Physiol 77:2391-2399.
14. Lillywhite H.B., K.C. Zippel, and A.P. Farrell. 1999. Resting and maximal heart rates in ectothermic vertebrates. Comp Biochem Physiol A 124:369-382.
15. Lubbe W.F., T. Podzuweit, and L.H. Opie. 1992. Potential arrhythmogenic role of cyclic adenosine monophosphate (AMP) and cytosolic calcium overload: implications for prophylactic effects of beta-blockers in myocardial infarction and proarrhythmic effects of phosphodiesterase inhibitors. J Am Coll Cardiol 19:1622-1633.
16. Mallet R.T. 2000. Pyruvate: metabolic protector of cardiac performance. Exp Biol Med 223:136-148.
17. McDonald D.G., R.G. Boutilier, and D.P. Toews. 1980. The effects of enforced activity on ventilation, circulation and blood acid-base balance in the semi-terrestrial anuran, Bufo marinus. J Exp Biol 84:273-287.
18. +] and adrenaline on force development, relaxation and membrane potential in cardiac muscle from freshwater turtle and rainbow trout. J Exp Biol 204:261-268.
19. o. Mol Physiol 5:189-198.
20. Nielsen O.B., F. de Paoli, and K. Overgaard. 2001. Protective effects of lactic acid on force production in rat skeletal muscle. J Physiol 536:161-166.
21. O'Neill M. and D.J. Paterson. 1995. Role of the sympathetic nervous system in cardiac performance during hyperkalemia in the anaesthetized pig. Acta Physiol Scand 153:1-11.
22. +, acid, norepinephrine, and ischemia on the heart: implications for exercise. J Appl Physiol 82:1046-1052.
23. Orchard C.H. and J.C. Kentish 1990. Effects of changes of pH on the contractile function of cardiac muscle. Am J Physiol 258:C967-C981.
24. Paterson D.J., G.J. Blake, S.P. Leitch, S.M. Phillips, and H.F. Brown. 1992. Effects of catecholamines and potassium on cardiovascular performance in the rabbit. J Appl Physiol 73:1413-1418.
25. Paterson D.J., J. Rogers, T. Powell, and H.F. Brown. 1993. Effect of catecholamines on the ventricular myocyte action-potential in raised extracellular potassium. Acta Physiol Scand 148:177-186.
26. + in the frog heart. Acta Physiol Scand 151:417-419.
27. o in the rabbit. Acta Physiol Scand 156:419-427.
28. Sejersted O.M. and G. Sjøgaard. 2000. Dynamics and consequences of potassium shifts in skeletal muscle and heart during exercise. Physiol Rev 80:1411-1481.
29. Smith H.W. 1926. The actions of acids on turtle heart muscle with reference to the penetration of anions. Am J Physiol 76:411-447.
30. Tufts B.L., D.C. Mense, and D.J. Randall. 1987. The effects of forced activity on circulating catecholamines and pH and water content of erythrocytes in the toad. J Exp Biol 128:411-418.
31. Van Hall G. 2000. Lactate as a fuel for mitochondrial respiration. Acta Physiol Scand 168:643-656.
32. Wahlqvist I. and G. CampbelL 1988. Autonomic influences on heart rate and blood pressure in the toad, Bufo marinus, at rest and during exercise. J Exp Biol 134:377-396.