Randomized controlled trial of prenatal zinc supplementation and the development of fetal heart rate

American Journal of Obstetrics and Gynecology

Volumn 190, Issue 4, 2004, Pages 1106-1112

  Merialdi, Mario ^a,b   Caulfield, Laura E ^a   Zavaleta, Nelly ^c   Figueroa, Alberto ^c   Dominici, Francesca ^a   Dipietro, Janet A ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b WORLD HEALTH ORGANIZATION   (Switzerland)

^c INSTITUTO DE INVESTIGACIÓN NUTRICIONAL   (Peru)

Author keywords

Autonomie function; Cardiac development; Central nervous system; Fetal development; Peru; Zinc

Indexed keywords

FOLIC ACID; IRON; ZINC;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; ELECTRONICS; EVALUATION; FETUS; FETUS DEVELOPMENT; FETUS HEART RATE; FETUS MONITORING; FETUS MOVEMENT; GESTATION PERIOD; HEART DEVELOPMENT; HUMAN; LOWEST INCOME GROUP; MOTOR ACTIVITY; NORMAL HUMAN; PERU; PREGNANCY COMPLICATION; PRENATAL PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VITAMIN SUPPLEMENTATION;

EID: 2342443320     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2003.09.072     Document Type: Article

References (26)

1. Frederickson CJ, Suh SW, Silva D, Frederickson CJ, Thompson RB. Importance of zinc in the central nervous system: the zinc-containing neuron. J Nutr 2000;130(Suppl):1471S-83S.
2. Golub MS, Keen CL, Gershwin ME, Hendrickx AG. Developmental zinc deficiency and behavior. J Nutr 1995;125(Suppl):2263S-71S.
3. Kirksey A, Rahmanifar A, Wachs TD, McCabe GP, Bassily NS, Bishry Z, et al. Determinants of pregnancy outcome and newborn behavior in a semirural Egyptian population. Am J Clin Nutr 1991;54:657-67.
4. Caulfield LE, Zavaleta N, Shankar A, Merialdi M. The potential contribution of maternal zinc supplementation to child survival programs. Am J Clin Nutr 1998;68(Suppl):499S-508S.
5. Hepper PG. Fetal behavior and neural functioning. In: Lecanuet JP, Fifer WP, Krasnegor NA, Smotherman WP, editors. Fetal development: a psychobiological perspective. Hillsdale, NJ: Lawrence Erlbaum Associates; 1995. p. 405-17.
6. Prechtl HFR. Continuity and change in early neural development. In: Prechtl HFR, editor. Continuity of neural function to prenatal to postnatal life. Philadelphia: Lippincott; 1984. p. 1-15.
7. Parer JT. Fetal heart rate. In: Creasy RK, Resnik R, editors. Maternal-fetal medicine. 4th ed. Philadelphia: WB Saunders; 1999. p. 270-99.
8. Dawes GS, Houghton CW, Redman CW, Visser GH. Pattern of the normal human fetal heart rate. BJOG 1982;89:276-84.
9. Gagnon R, Campbell K, Hunse C, Patrick J. Patterns of human fetal heart rate accelerations from 26 weeks to term. Am J Obstet Gynecol 1987;157:743-9.
10. Merialdi M, Caulfield LE, Zavaleta N, Figueroa A, DiPietro JA. Adding zinc to prenatal iron and folate supplements improves fetal neurobehavioral development. Am J Obstet Gynecol 1999;180:483-90.
11. Caulfield LE, Zavaleta N, Figueroa A. Adding zinc to prenatal iron and folate supplements improves maternal and neonatal zinc status in a Peruvian population. Am J Clin Nutr 1999;69:1257-63.
12. Sacco LM, Caulfield LE, Zavaleta N, Retamozo L. Dietary pattern and usual nutrient intakes of Peruvian women during pregnancy. Eur J Clin Nutr 2003;57:1492-7.
13. DiPietro JA. Fetal neurobehavioral development. In: Zeskind P, Singer L, editors. Biobehavioral assessment of the newborn and young infant. New York: Guilford Publications; 2001. p. 43-80.
14. Besinger RE, Johnson TRB. Doppler recordings of fetal movement: clinical correlation with real-time ultrasound. Obstet Gynecol 1989;74:277-80.
15. DiPietro JA, Costigan KA, Pressman EK. Fetal movement detection: comparison of the Toitu actograph with ultrasound from 20 weeks gestation. J Matern Fetal Med 1999;8:237-42.
16. Diggle PJ, KungYee L, Zeger SL. Analysis of longitudinal data. Oxford: Oxford University Press; 1994 p. 45, 151-2.
17. Almi CR, Ball RH, Wheller ME. Human fetal and neonatal movement patterns: gender differences and fetal-to-neonatal continuity. Dev Psychobiol 2001;38:252-73.
18. DiPietro JA, Bornstein MH, Costigan KA, Pressman EK, Hahn CS, Painter K, et al. What does fetal movement predict about behavior during the first two years of life? Dev Psychobiol 2002;40:358-71.
19. Terao T, Kawashima Y, Noto H, Inamoto Y, Lin TY, Sumimoto K, et al. Neurological control of fetal heart rate in 20 cases of anencephalic fetuses. Am J Obstet Gynecol 1984;149:201-8.
20. Peleg D, Goldman JA. Fetal heart patterns: a study of the anencephalic fetus. Obstet Gynecol 1979;53:530-3.
21. Kurauchi O, Ishida T, Ohno Y, Ando H, Nomura S, Mizutani S, et al. Serial fetal heart rate monitoring in monozygotic twin, one of which was anencephalic. Arch Gynecol Obstet 1995;256:53-6.
22. Yoshizato T, Koyanagi T, Takashima TSS, Akazawa K, Nakano H. The relationship between age-related heart rate changes and developing brain function: a model of anencephalic human fetuses in utero. Ear Hum Dev 1994;36:101-12.
23. DiPietro JA, Costigan KA, Pressman EK, Doussard-Roosevelt J. Antenatal origins of individual differences in heart rate. Dev Psychobiol 2000;37:221-8.
24. Bornstein M, DiPietro J, Hahn C, Painter K, Haynes O, Costigan K. Prenatal cardiac function and postnatal cognitive development: an exploratory study. Infancy 2002;3:475-94.
25. Snidman N, Kagan J, Riordan L, Shannon D. Cardiac function and behavioral reactivity during infancy. Psychophysiol 1995;32:199-207.
26. Caulfield LE, Zavaleta N, Figueroa A, Leon Z. Maternal zinc supplementation does not affect size at birth or pregnancy duration in Peru. J Nutr 1999;129:1563-8.