-
1
-
-
0033653261
-
For how long is brain tissue salvageable? Imaging-based evidence
-
Baron J-C, Moseley ME: For how long is brain tissue salvageable? Imaging-based evidence. J Stroke Cerebrovasc Dis (2000) 9(6):15-20.
-
(2000)
J. Stroke Cerebrovasc. Dis.
, vol.9
, Issue.6
, pp. 15-20
-
-
Baron, J.-C.1
Moseley, M.E.2
-
2
-
-
0037224703
-
Adventures in the pathophysiology of brain ischemia: Penumbra, gene expression, neuroprotection: The 2002 Thomas Willis lecture
-
Ginsberg MD: Adventures in the pathophysiology of brain ischemia: Penumbra, gene expression, neuroprotection: The 2002 Thomas Willis lecture. Stroke (2003) 34(1):214-223.
-
(2003)
Stroke
, vol.34
, Issue.1
, pp. 214-223
-
-
Ginsberg, M.D.1
-
3
-
-
0028806656
-
Massive persistent release of excitatory amino acids following human occlusive stroke
-
Bullock R, Zauner A, Woodward J, Young HF: Massive persistent release of excitatory amino acids following human occlusive stroke. Stroke (1995) 26(11):2187-2189.
-
(1995)
Stroke
, vol.26
, Issue.11
, pp. 2187-2189
-
-
Bullock, R.1
Zauner, A.2
Woodward, J.3
Young, H.F.4
-
4
-
-
0000452931
-
Nitroxide radical adducts in biology: Chemistry applications, and pitfalls
-
Berliner LJ, Reuben J (Eds), Plenum Publishing, New York, NY, USA
-
Mottley C, Mason RP: Nitroxide radical adducts in biology: Chemistry applications, and pitfalls. In: Biological Magnetic Resonance. Berliner LJ, Reuben J (Eds), Plenum Publishing, New York, NY, USA (1999) 8:489-546.
-
(1999)
Biological Magnetic Resonance
, vol.8
, pp. 489-546
-
-
Mottley, C.1
Mason, R.P.2
-
5
-
-
0030901284
-
Induction of ischemic tolerance and antioxidant activity by brief focal ischemia
-
Toyoda T, Kassell NF, Lee KS: Induction of ischemic tolerance and antioxidant activity by brief focal ischemia. Neuroreport (1997) 8(4):847-851.
-
(1997)
Neuroreport
, vol.8
, Issue.4
, pp. 847-851
-
-
Toyoda, T.1
Kassell, N.F.2
Lee, K.S.3
-
6
-
-
0034708706
-
Spermine is neuroprotective against anoxia and N-methyI-D-aspartate in hippocampal slices
-
Ferchmin PA, Pérez D, Biello M: Spermine is neuroprotective against anoxia and N-methyI-D-aspartate in hippocampal slices. Brain Res (2000) 859(2):273-279.
-
(2000)
Brain Res.
, vol.859
, Issue.2
, pp. 273-279
-
-
Ferchmin, P.A.1
Pérez, D.2
Biello, M.3
-
7
-
-
0037205108
-
Polyamines and central nervous system injury: Spermine and spermidine decrease following transient focal cerebral ischemia in spontaneously hypertensive rats
-
Adibhatla RM, Hatcher JF, Sailor K, Dempsey RJ: Polyamines and central nervous system injury: Spermine and spermidine decrease following transient focal cerebral ischemia in spontaneously hypertensive rats. Brain Res (2002) 938(1-2):81-86.
-
(2002)
Brain Res.
, vol.938
, Issue.1-2
, pp. 81-86
-
-
Adibhatla, R.M.1
Hatcher, J.F.2
Sailor, K.3
Dempsey, R.J.4
-
8
-
-
0028187682
-
Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage
-
Hall ED, McCall JM, Means ED: Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage. Adv Pharmacol (1994) 28:221-268.
-
(1994)
Adv. Pharmacol.
, vol.28
, pp. 221-268
-
-
Hall, E.D.1
McCall, J.M.2
Means, E.D.3
-
9
-
-
0035200537
-
Effects of the nitrone radical scavengers PBN and S-PBN on in vivo trapping of reactive oxygen species after traumatic brain injury in rats
-
Marklund N, Lewander T, Clausen F, Hillered L: Effects of the nitrone radical scavengers PBN and S-PBN on in vivo trapping of reactive oxygen species after traumatic brain injury in rats. J Cereb Blood Flow Metab (2001) 21(11):1259-1267.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, Issue.11
, pp. 1259-1267
-
-
Marklund, N.1
Lewander, T.2
Clausen, F.3
Hillered, L.4
-
10
-
-
0032806959
-
Dynamics of cerebral injury, perfusion, and blood-brain barrier changes after temporary and permanent middle cerebral artery occlusion in the rat
-
Kastrup A, Engelhorn T, Beaulieu C, de Crespigny A, Moseley ME: Dynamics of cerebral injury, perfusion, and blood-brain barrier changes after temporary and permanent middle cerebral artery occlusion in the rat. J Neurol Sci (1999) 166(2):91-99.
-
(1999)
J. Neurol. Sci.
, vol.166
, Issue.2
, pp. 91-99
-
-
Kastrup, A.1
Engelhorn, T.2
Beaulieu, C.3
de Crespigny, A.4
Moseley, M.E.5
-
11
-
-
0032925674
-
Combination of hypoxia/aglycemia compromises in vitro blood-brain barrier integrity
-
Abbruscato TJ, Davis TP: Combination of hypoxia/aglycemia compromises in vitro blood-brain barrier integrity. J Pharmacol Exp Ther (1999) 289(2):668-675.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, Issue.2
, pp. 668-675
-
-
Abbruscato, T.J.1
Davis, T.P.2
-
12
-
-
0035054659
-
Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059
-
Maples KR, Ma F, Zhang Y-K: Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059. Free Radic Res (2001) 34(4):417-426.
-
(2001)
Free Radic. Res.
, vol.34
, Issue.4
, pp. 417-426
-
-
Maples, K.R.1
Ma, F.2
Zhang, Y.-K.3
-
13
-
-
84935138208
-
In vivo detection of free radical metabolites by spin trapping
-
Symons MCR (Ed) London, UK Royal Society of Chemistry
-
Mason RP, Maples KR, Knecht KT: In vivo detection of free radical metabolites by spin trapping. In: Electron Spin Resonance. Symons MCR (Ed), Royal Society of Chemistry, London, UK (1999) 11B:1-10.
-
(1999)
Electron. Spin Resonance
, vol.11 B
, pp. 1-10
-
-
Mason, R.P.1
Maples, K.R.2
Knecht, K.T.3
-
14
-
-
0028181531
-
α-Phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia
-
Cao X, Phillis JW: α-Phenyl-tert-butyl-nitrone reduces cortical infarct and edema in rats subjected to focal ischemia. Brain Res (1994) 644(2):267-272.
-
(1994)
Brain Res.
, vol.644
, Issue.2
, pp. 267-272
-
-
Cao, X.1
Phillis, J.W.2
-
15
-
-
0033502692
-
Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat
-
Kuroda S, Tsuchidate R, Smith M-L, Maples KR, Siesjö BK: Neuroprotective effects of a novel nitrone, NXY-059, after transient focal cerebral ischemia in the rat. J Cereb Blood Flow Metab (1999) 19(7):778-787.
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, Issue.7
, pp. 778-787
-
-
Kuroda, S.1
Tsuchidate, R.2
Smith, M.-L.3
Maples, K.R.4
Siesjö, B.K.5
-
16
-
-
0035134434
-
Efficacy of disodium 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (NXY-059), a free radical trapping agent, in a rat model of hemorrhagic stroke
-
Peeling J, Del Bigio MR, Corbett D, Green AR, Jackson DM: Efficacy of disodium 4-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (NXY-059), a free radical trapping agent, in a rat model of hemorrhagic stroke. Neuropharmacology (2001) 40(3):433-439.
-
(2001)
Neuropharmacology
, vol.40
, Issue.3
, pp. 433-439
-
-
Peeling, J.1
Del Bigio, M.R.2
Corbett, D.3
Green, A.R.4
Jackson, D.M.5
-
17
-
-
0035800578
-
NXY-059, a novel free radical trapping compound, reduces cortical infarction after permanent focal cerebral ischemia in the rat
-
Zhao A, Cheng M, Maples KR, Ma JY, Buchan AM: NXY-059, a novel free radical trapping compound, reduces cortical infarction after permanent focal cerebral ischemia in the rat. Brain Res (2001) 909(1-2):46-50.
-
(2001)
Brain Res.
, vol.909
, Issue.1-2
, pp. 46-50
-
-
Zhao, A.1
Cheng, M.2
Maples, K.R.3
Ma, J.Y.4
Buchan, A.M.5
-
18
-
-
0034073967
-
Neuroprotection by 2-h postischemia administration of two free radical scavengers, α-phenyl-N-tert-butyl-nitrone (PBN) and N-tert-butyl-(2-sulfophenyl)-nitrone (S-PBN), in rats subjected to focal embolic cerebral ischemia
-
Yang Y, Li Q, Shuaib A: Neuroprotection by 2-h postischemia administration of two free radical scavengers, α-phenyl-N-tert-butyl-nitrone (PBN) and N-tert-butyl-(2-sulfophenyl)-nitrone (S-PBN), in rats subjected to focal embolic cerebral ischemia. Exp Neurol (2000) 163(1):39-45.
-
(2000)
Exp. Neurol.
, vol.163
, Issue.1
, pp. 39-45
-
-
Yang, Y.1
Li, Q.2
Shuaib, A.3
-
19
-
-
0036281174
-
Effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) on intracerebral hemorrhage in a rabbit large clot embolic stroke model: Combination studies with tissue plasminogen activator
-
Lapchak PA, Araujo DM, Song D, Wei J, Purdy R, Zivin JA: Effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) on intracerebral hemorrhage in a rabbit large clot embolic stroke model: Combination studies with tissue plasminogen activator. Stroke (2002) 33(6):1665-1670.
-
(2002)
Stroke
, vol.33
, Issue.6
, pp. 1665-1670
-
-
Lapchak, P.A.1
Araujo, D.M.2
Song, D.3
Wei, J.4
Purdy, R.5
Zivin, J.A.6
-
20
-
-
0036152938
-
Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window
-
Sydserff SG, Borelli AR, Green AR, Cross AJ: Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window. Br J Pharmacol (2002) 135(1):103-112.
-
(2002)
Br. J. Pharmacol.
, vol.135
, Issue.1
, pp. 103-112
-
-
Sydserff, S.G.1
Borelli, A.R.2
Green, A.R.3
Cross, A.J.4
-
21
-
-
0142070852
-
Neuroprotective effects of nitrone radical scavenger S-PBN on reperfusion nerve injury in rats
-
Gray C, Nukada H, Jackson DM, McMorran PD, Wu A, Ma F: Neuroprotective effects of nitrone radical scavenger S-PBN on reperfusion nerve injury in rats. Brain Res (2003) 982(2):179-185.
-
(2003)
Brain Res.
, vol.982
, Issue.2
, pp. 179-185
-
-
Gray, C.1
Nukada, H.2
Jackson, D.M.3
McMorran, P.D.4
Wu, A.5
Ma, F.6
-
22
-
-
0032102275
-
Nitrone spin traps and their pyrrolidine analogs in myocardial reperfusion injury: Hemodynamic and ESR implications - Evidence for a cardioprotective phosphonate effect for 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide in rat hearts
-
Pietri S, Liebgott T, Frejaville C, Tordo P, Culcasi M: Nitrone spin traps and their pyrrolidine analogs in myocardial reperfusion injury: Hemodynamic and ESR implications - evidence for a cardioprotective phosphonate effect for 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide in rat hearts. Eur J Biochem (1998) 254(2):256-265.
-
(1998)
Eur. J. Biochem.
, vol.254
, Issue.2
, pp. 256-265
-
-
Pietri, S.1
Liebgott, T.2
Frejaville, C.3
Tordo, P.4
Culcasi, M.5
-
23
-
-
0035206665
-
Isolated perfused rat hearts release secondary free radicals during ischemia reperfusion injury: Cardiovascular effects of the spin trap α-phenyl N-tert-butylnitrone
-
Vergely C, Tabard A, Maupoil V, Rochette L: Isolated perfused rat hearts release secondary free radicals during ischemia reperfusion injury: Cardiovascular effects of the spin trap α-phenyl N-tert-butylnitrone. Free Radical Res (2001) 35(5):475-489.
-
(2001)
Free Radical. Res.
, vol.35
, Issue.5
, pp. 475-489
-
-
Vergely, C.1
Tabard, A.2
Maupoil, V.3
Rochette, L.4
-
24
-
-
0034721770
-
Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species
-
Kotamraju S, Konorev EA, Joseph J, Kalyanaraman B: Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species. J Biol Chem (2000) 275(43):33585-33592.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.43
, pp. 33585-33592
-
-
Kotamraju, S.1
Konorev, E.A.2
Joseph, J.3
Kalyanaraman, B.4
-
25
-
-
0042837942
-
Stilbazulenyl nitrone, a novel antioxidant, is highly protective in focal ischemia
-
Ginsberg MD, Becker DA, Busto R, Belayev A, Zhang Y, Khoutorova L, Ley JJ, Zhao W, Belayev L: Stilbazulenyl nitrone, a novel antioxidant, is highly protective in focal ischemia. Ann Neurol (2003) 54(3):330-342.
-
(2003)
Ann. Neurol.
, vol.54
, Issue.3
, pp. 330-342
-
-
Ginsberg, M.D.1
Becker, D.A.2
Busto, R.3
Belayev, A.4
Zhang, Y.5
Khoutorova, L.6
Ley, J.J.7
Zhao, W.8
Belayev, L.9
-
26
-
-
0035797132
-
Targeting large molecules to mitochondria
-
Muratovska A, Lightowlers RN, Taylor RW, Wilce JA, Murphy MP: Targeting large molecules to mitochondria. Adv Drug Deliv Rev (2001) 49(1-2):189-198.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.49
, Issue.1-2
, pp. 189-198
-
-
Muratovska, A.1
Lightowlers, R.N.2
Taylor, R.W.3
Wilce, J.A.4
Murphy, M.P.5
-
27
-
-
0042627941
-
Improvement of peripheral endothelial dysfunction by acute vitamin C application: Different effects in patients with coronary artery disease,. ischemic, and dilated cardiomyopathy
-
Erbs S, Gielen S, Linke A, Mobius-Winkler S, Adams V, Baither Y, Schuler G, Hambrecht R: Improvement of peripheral endothelial dysfunction by acute vitamin C application: Different effects in patients with coronary artery disease, ischemic, and dilated cardiomyopathy. Am Heart J (2003) 146(2):280-285.
-
(2003)
Am. Heart J.
, vol.146
, Issue.2
, pp. 280-285
-
-
Erbs, S.1
Gielen, S.2
Linke, A.3
Mobius-Winkler, S.4
Adams, V.5
Baither, Y.6
Schuler, G.7
Hambrecht, R.8
-
28
-
-
0037167715
-
Heat shock protein 72 enhances manganese superoxide dismutase activity during myocardial ischemia-reperfusion injury, associated with mitochondrial protection and apoptosis reduction
-
Suzuki K, Murtuza B, Sammut IA, Latif N, Jayakumar J, Smolenski RT, Kaneda Y, Sawa Y, Matsuda H, Yacoub MH: Heat shock protein 72 enhances manganese superoxide dismutase activity during myocardial ischemia-reperfusion injury, associated with mitochondrial protection and apoptosis reduction. Circulation (2002) 106(12 Suppl 1):1270-1276.
-
(2002)
Circulation
, vol.106
, Issue.12 SUPPL. 1
, pp. 1270-1276
-
-
Suzuki, K.1
Murtuza, B.2
Sammut, I.A.3
Latif, N.4
Jayakumar, J.5
Smolenski, R.T.6
Kaneda, Y.7
Sawa, Y.8
Matsuda, H.9
Yacoub, M.H.10
-
29
-
-
0345118252
-
Nitrones as neuroprotective agents in cerebral ischemia, with particular reference to NXY-059
-
Green AR, Ashwood T, Odergren T, Jackson DM: Nitrones as neuroprotective agents in cerebral ischemia, with particular reference to NXY-059. Pharmacol Ther (2003) 100(3):195-214.
-
(2003)
Pharmacol. Ther.
, vol.100
, Issue.3
, pp. 195-214
-
-
Green, A.R.1
Ashwood, T.2
Odergren, T.3
Jackson, D.M.4
-
30
-
-
0037319241
-
Tolerability of NXY-059 at higher target concentrations in patients with acute stroke
-
Lees KR, Barer D, Ford GA, Hacke W, Kostulas V, Sharma AK, Odergren T: Tolerability of NXY-059 at higher target concentrations in patients with acute stroke. Stroke (2003) 34(2):482-487.
-
(2003)
Stroke
, vol.34
, Issue.2
, pp. 482-487
-
-
Lees, K.R.1
Barer, D.2
Ford, G.A.3
Hacke, W.4
Kostulas, V.5
Sharma, A.K.6
Odergren, T.7
-
31
-
-
0042919342
-
Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion
-
Marshall JW, Cummings RM, Bowes LJ, Ridley RM, Green AR: Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion. Stroke (2003) 34(9):2228-2233.
-
(2003)
Stroke
, vol.34
, Issue.9
, pp. 2228-2233
-
-
Marshall, J.W.1
Cummings, R.M.2
Bowes, L.J.3
Ridley, R.M.4
Green, A.R.5
|