Y-box-binding protein-1 expression is not correlated with p53 expression but with proliferating cell nuclear antigen expression in non-small cell lung cancer

Anticancer Research

Volumn 25, Issue 5, 2005, Pages 3437-3443

  Yoshimatsu, Takashi ^a   Uramoto, Hidetaka ^a   Oyama, Tsunehiro ^a,c   Yashima, Yasunori ^a   Gu, Chundong ^b   Morita, Masaru ^a   Sugio, Kenji ^a   Kohno, Kimitoshi ^a   Yasumoto, Kosei ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Lung cancer; p53; PCNA; YB 1

Indexed keywords

CCAAT BINDING FACTOR; CYCLINE; PROTEIN P53; Y BOX BINDING PROTEIN 1;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CELL PROLIFERATION; DNA REPAIR; FEMALE; GENETIC TRANSCRIPTION; GROWTH REGULATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LABELING INDEX; LARGE CELL CARCINOMA; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DNA BINDING; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CCAAT-ENHANCER-BINDING PROTEINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MIDDLE AGED; NFI TRANSCRIPTION FACTORS; PROGNOSIS; PROLIFERATING CELL NUCLEAR ANTIGEN; SURVIVAL RATE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; Y-BOX-BINDING PROTEIN 1;

EID: 23344439484     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Ginsberg R, Yokes E and Raben A: Non-small cell lung cancer. In: Cancer, Principles and Practice of Oncology (De Vita V, Jr, Helleman S and Rosenberg S, eds.). Philadelphia, Lippencott-Raven, pp. 858-911, 1997.
2. Hara N, Nakanishi Y and Izumi M: Epidemiology of lung cancer in Japan. Nippon Rinsho 58: 1005-1011, 2000.
3. Mountain CF: Revisions in the International System for Staging Lung Cancer. Chest 111: 1710-1717, 1997.
4. Martini N, Bains MS, Burt ME, Zakowski MF, McCormack P, Rusch VW and Ginsberg RJ: Incidence of local recurrence and second primary tumors in resected stage I lung cancer. J Thorac Cardiovasc Surg 109: 120-129, 1995.
5. Strauss GM, Kwiatkowski DJ, Harpole DH, Lynch TJ, Skarin AT and Sugarbaker DJ: Molecular and pathologic markers in stage I non-small-cell carcinoma of the lung. J Clin Oncol 13: 1265-1279, 1995.
6. Wang G, Reed E and Li QQ: Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer. Oncol Rep 5: 955-965, 2004.
7. Kohno K, Izumi H, Uchiumi T, Ashizuka M and Kuwano M: The pleiotropic functions of the Y-box-binding protein, YB-1. Bioessays 7: 691-698, 2003.
8. Kuwano M, Uchiumi T, Hayakawa H, Ono M, Wada M, Izumi H and Kohno K: The basic and clinical implications of ABC transporters, Y-box-binding protein-1 (YB-1) and angiogenesis-related factors in human malignancies. Cancer Sci 1: 9-14, 2003.
9. Ise T, Nagatani G, Imamura T, Kato K, Takano H, Nomoto M, Izumi H, Ohmori H, Okamoto T, Ohga T, Uchiumi T, Kuwano M and Kohno K: Transcription factor Y-box binding protein 1 binds preferentially to cisplatin-modified DNA and interacts with proliferating cell nuclear antigen. Cancer Res 59: 342-346, 1999.
10. Okamoto T, Izumi H, Imamura T, Takano H, Ise T, Uchiumi T, Kuwano M and Kohno K: Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression. Oncogene 19: 6194-6202, 2000.
11. Uramoto H, Izumi H, Ise T, Tada M, Uchiumi T, Kuwano M, Yasumoto K, Funa K and Kohno K: p73 interacts with c-Myc to regulate Y-box-binding protein-1 expression. J Biol Chem 277: 31694-31702, 2002.
12. Uramoto H, Izumi H, Nagatani G, Ohmori H, Nagasue N, Ise T, Yoshida T, Yasumoto K and Kohno K: Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression. Biochem J 371: 301-310, 2003.
13. Bargou RC, Jurchott K, Wagener C, Bergmann S, Metzner S, Bommert K, Mapara MY, Winzer KJ, Dietel M, Dorken B and Royer HD: Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression. Nature Med 3: 447-450, 1997.
14. Oda Y, Sakamoto A, Shinohara N, Ohga T, Uchiumi T, Kohno K, Tsuneyoshi M, Kuwano M and Iwamoto Y: Nuclear expression of YB-1 protein correlates with P-glycoprotein expression in human osteosarcoma. Clin Cancer Res 4: 2273-2277, 1998.
15. Kamura T, Yahata H, Amada S, Ogawa S, Sonoda T, Kobayashi H, Mitsumoto M, Kohno K, Kuwano M and Nakano H: Is nuclear expression of Y box-binding protein-1 a new prognostic factor in ovarian serous adenocarcinoma? Cancer 85: 2450-2454, 1999.
16. Shibao K, Takano H, Nakayama Y, Okazaki, Nagata N, Izumi H, Uchiumi T, Kuwano M, Kohno K and Itoh H: Enhanced coexpression of YB-1 and DNA topoisomerase II alpha genes in human colorectal carcinomas. Int J Cancer 83: 732-737, 1999.
17. Shibahara K, Sugio K, Osaki T, Uchiumi T, Maehara Y, Kohno K, Yasumoto K, Sugimachi K and Kuwano M: Nuclear expression of the Y-box binding protein, YB-1, as a novel marker of disease progression in non-small cell lung cancer. Clin Cancer Res 7: 3151-3155, 2001.
18. Bravo R, Frank R, Blundell PA and Macdonald-Bravo H: Cyclin/PCNA is the auxiliary protein of DNA polymerase-delta. Nature 326: 515-517, 1987.
19. Iwatani Y, Kamigaki T, Suzuki S, Ohno M, Nakamura T and Kuroda Y: Proliferating cell nuclear antigen as a predictor of therapeutic effect of continuous 5-fluorouracil administration in gastric cancer. Int J Oncol 14: 965-970, 1999.
20. Oyama T, Osaki T, Mitsudomi T, Ogawa R, Nakanishi R, Sugio K and Yasumoto K: p53 alteration, proliferating cell nuclear antigen, and nucleolar organizer regions in thymic epithelial tumors. Int J Mol Med 1: 823-826, 1998.
21. Dobashi K, Sugio K, Osaki T, Oka T and Yasumoto K: Micrometastatic p53-positive cells in the lymph nodes of non-small-cell lung cancer: prognostic significance. J Thorac Cardiovasc Surg 114: 339-346, 1997.
22. Ohga T, Koike K, Ono M, Makino Y, Itagaki Y, Tanimoto M, Kuwano M and Kohno K: Role of the human Y box-binding protein YB-1 in cellular sensitivity to the DNA-damaging agents cisplatin, mitomycin C, and ultraviolet light. Cancer Res 56: 4224-4228, 1996.
23. Gu C, Oyama T, Osaki T, Kohno K and Yasumoto K: Expression of Y box-binding protein-1 correlates with DNA topoisomerase IIalpha and proliferating cell nuclear antigen expression in lung cancer. Anticancer Res 4A: 2357-2362, 2001.
24. Uramoto H, Osaki T, Inoue M, Taga S, Takenoyama M, Hanagiri T, Yoshino I, Nakanishi R, Ichiyoshi Y and Yasumoto K: Fas expression in non-small cell lung cancer: its prognostic effect in completely resected stage III patients. Eur J Cancer 35: 1462-1465, 1999.
25. Kaplan E and Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53: 457-481, 1958.
26. Peto R, Pike MC, Armitage P, Breslow NE, Cox DR, Howard SV, Mantel N, McPherson K, Peto J and Smith PG: Design and analysis of randomised clinical trials requiring prolonged observation of each patient. Br J Cancer 35: 1-39, 1977.
27. Wolffe A, Tafuri S, Ranjan M and Familari M: The Y-box factors: a family of nucleic acid binding proteins conserved from Escherichia coli to man. New Biol 4: 290-298, 1992.
28. Wolffe A: Structural and functional properties of the evolutionarily ancient Y-box family of nucleic acid binding proteins. Bioessays 16: 245-251, 1994.
29. Swamynathan S, Nambiar A and Guntaka R: Role of single-stranded DNA regions and Y-box proteins in transcriptional regulation of viral and cellular genes. FASEB J 12: 515-522, 1998.
30. Izumi H, Imamura T, Nagatani G, Ise T, Murakami T, Uramoto H, Torigoe T, Ishiguchi H, Yoshida Y, Nomoto M, Okamoto T, Uchiumi T, Kuwano M, Funa K and Kohno K: Y box-binding protein-1 binds preferentially to single-stranded nucleic acids and exhibits 3'→5' exonuclease activity. Nucleic Acids Res 29: 1200-1207, 2001.
31. Okamoto T, Izumi H, Imamura T, Takano H, Ise T, Uchiumi T, Kuwano M and Kohno K: Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression. Oncogene 19: 6194-6202, 2000.
32. Ohga T, Uchiumi T, Makino Y, Koike K, Wada M, Kuwano M and Kohno K: Direct involvement of the Y-box binding protein YB-1 in genotoxic stress-induced activation of the human multidrug resistance 1 gene. J Biol Chem 273: 5997-6000, 1998.
33. Imoto H, Osaki T, Taga S, Ohgami A, Ichiyoshi Y and Yasumoto K: Vascular endothelial growth factor expression in non-small-cell lung cancer: prognostic significance in squamous cell carcinoma. J Thorac Cardiovasc Surg 115: 1007-1014, 1998.
34. Gu C, Osaki T, Oyama T, Inoue M, Kodate M, Dobashi K, Oka T and Yasumoto K: Detection of micrometastatic tumor cells in pNO lymph nodes of patients with completely resected nonsmall cell lung cancer: impact on recurrence and survival. Ann Surg 235: 133-139, 2002.
35. Osaki T, Oyama T, Gu CD, Yamashita T, So T, Takenoyama M, Sugio K and Yasumoto K: Prognostic impact of micrometastatic tumor cells in the lymph nodes and bone marrow of patients with completely resected stage I non-small-cell lung cancer. J Clin Oncol 20: 2930-2936, 2002.
36. Yasumoto K, Osaki T, Watanabe Y, Kato H and Yoshimura T: Prognostic value of cytokeratin-positive cells in the bone marrow and lymph nodes of patients with resected non-small cell lung cancer: a multicenter prospective study. Ann Thorac Surg 76: 194-201, 2003.
37. Inoue M, Osaki T, Noguchi M, Hirohashi S, Yasumoto K and Kasai H: Lung cancer patients have increased 8-hydroxydeoxyguanosine levels in peripheral lung tissue DNA. Jpn J Cancer Res 89: 691-695, 1998.
38. Osaki T, Mitsudomi T, Oyama T, Nakanishi R and Yasumoto K: Serum level and tissue expression of c-erbB-2 protein in lung adenocarcinoma. Chest 108: 157-162, 1995.
39. Mitsudomi T, Oyama T, Nishida K, Ogami A, Osaki T, Sugio K, Yasumoto K, Sugimachi K and Gazdar AF: Loss of heterozygosity at 3p in non-small cell lung cancer and its prognostic implication. Clin Cancer Res 2: 1185-1189, 1996.
40. Sugio K, Ishida T, Yokoyama H, Inoue T, Sugimachi K and Sasazuki T: Ras gene mutations as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis. Cancer Res 52: 2903-2906, 1992.
41. Sugio K, Inoue T, Inoue K, Yaita H, Inuzuka S, Ishida T and Sugimachi K: Different site mutation of the K-ras gene in a patient with metachronous double lung cancers. Anticancer Res 13: 2469-2471, 1993.
42. Taga S, Osaki T, Ohgami A, Imoto H and Yasumoto K: Prognostic impact of telomerase activity in non-small cell lung cancers. Ann Surg 230: 715-720, 1999.
43. Uramoto H, Sugio K, Oyama T, Nakata S, Ono K, Morita M, Funa K and Yasumoto K: Expression of deltaNp73 predicts poor prognosis in lung cancer. Clin Cancer Res 10: 6905-6911, 2004.