CD151 promotes neovascularization and improves blood perfusion in a rat hind-limb ischemia model

Journal of Endovascular Therapy

Volumn 12, Issue 4, 2005, Pages 469-478

  Lan, Rong Fang ^a   Liu, Zheng Xiang ^a   Liu, Xiao Chun ^b   Song, Yu E ^a   Wang, Dao Wen ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Arteriogenesis; CD151; Gene therapy; Ischemia model; Neovascularization; Rat hind limb

Indexed keywords

CD151 ANTIGEN; GENE PRODUCT; MEMBRANE PROTEIN; PARVOVIRUS VECTOR; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ENDOTHELIUM CELL; GENE EXPRESSION; GENE THERAPY; IMMUNOHISTOCHEMISTRY; LIMB ISCHEMIA; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; VASCULAR ENDOTHELIUM; VIRAL GENE THERAPY; VIRUS RECOMBINANT;

ANGIOGRAPHY; ANIMALS; ANTIGENS, CD; BIOPSY, NEEDLE; CYTOMEGALOVIRUS; DISEASE MODELS, ANIMAL; DNA, COMPLEMENTARY; ENDOTHELIUM, VASCULAR; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HINDLIMB; HUMANS; IMMUNOHISTOCHEMISTRY; ISCHEMIA; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; PROBABILITY; RANDOM ALLOCATION; RATS; RATS, WISTAR; REFERENCE VALUES; REGIONAL BLOOD FLOW; TREATMENT OUTCOME;

EID: 23344432116     PISSN: 15266028     EISSN: None     Source Type: Journal    
DOI: 10.1583/04-1478R.1     Document Type: Article

References (27)

1. Chang DS, Su H, Tang GL, et al. Adeno-associated viral vector-mediated gene transfer of VEGF normalizes skeletal muscle oxygen tension and induces arteriogenesis in ischemic rat hind limb. Mol Ther. 2003;7:44-51.
2. Shimpo M, Ikeda U, Maeda Y, et al. AAV-mediated VEGF gene transfer into skeletal muscle stimulates angiogenesis and improves blood flow in a rat hind limb ischemia model. Cardiovasc Res. 2002;53:993-1001.
3. Ho HK, Jang JJ, Kaji S, et al. Developmental endothelial locus-1 (Del-1), a novel angiogenic protein: its role in ischemia. Circulation. 2004; 109:1314-1319.
4. Mistry A, Harbottle R, Hart S, et al. Integrins and angiogenesis: unlocking the route to gene therapy. Curr Opin Mol Ther. 2003;5:603-610.
5. Kazarov AR, Yang X, Stipp CS, et al. An extracellular site on tetraspanin CD151 determines alpha 3 and alpha 6 integrin-dependent cellular morphology. J Cell Biol. 2002;158:1299-1309.
6. Zhang XA, Kazarov AR, Yang X, et al. Function of the tetraspanin CD151-α6β1 integrin complex during cellular morphogenesis. Mol Biol Cell. 2002;13:1-11.
7. Wang Z, Ma HI, Li J, et al. Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo. Gene Ther. 2003;10:2105-2111.
8. Xiao X, Li J, Samulski RJ. Production of high-titer recombinant adeno-associated virus vectors in the absence of helper virus. J Virol. 1998;72:2224-2232.
9. Wang T, Li H, Zhao C, et al. Recombinant adeno-associated virus-mediated kallikrein gene therapy reduces hypertension and attenuates its cardiovascular injuries. Gene Ther. 2004;11: 1342-1350.
10. Auricchio A, Hildinger M, O'Connor E, et al. Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column. Hum Gene Ther. 2001;12:71-76.
11. Chan VT, Fleming KA, McGee JO. Detection of sub-picogram quantities of specific DNA sequences on blot hybridization with biotinylated probes. Nucleic Acids Res. 1985;13:8083-8091.
12. Couffinhal T, Silver M, Zheng LP, et al. Mouse model of angiogenesis. Am J Pathol. 1998;152: 1667-1679.
13. Ubbink DT, Tulevski II, Jacobs MJ. Can the green laser Doppler measure skin-nutritive perfusion in patients with peripheral vascular disease? J Vasc Res. 2000;37:195-201.
14. Hershey JC, Baskin EP, Glass JD, et al. Revascularization in the rabbit hind limb: dissociation between capillary sprouting and arteriogenesis. Cardiovasc Res. 2001;49:618-625.
15. Takeshita S, Rossow ST, Kearney M, et al. Time course of increased cellular proliferation in collateral arteries after administration of vascular endothelial growth factor in a rabbit model of lower limb vascular insufficiency. Am J Pathol. 1995;147:1649-1660.
16. Hershey JC, Baskin EP, Corcoran HA, et al. Vascular endothelial growth factor stimulates angiogenesis without improving collateral blood flow following hind limb ischemia in rabbits. Heart Vessels. 2003;18:142-149.
17. Tokuhara T, Hasegawa H, Hattori N, et al. Clinical significance of CD151 gene expression in non-small cell lung cancer. Clin Cancer Res. 2001;7:4109-4114.
18. Berditchevski F. Complexes of tetraspanins with integrins: more than meets the eye. J Cell Sci. 2001;114:4143-4151.
19. Hemler ME. Specific tetraspanin functions. J Cell Biol. 2001;155:1103-1107.
20. Zhang XA, Bontrager AL, Hemler ME. Transmembrane-4 superfamily proteins associate with activated protein kinase C (PKC) and link PKC to specific beta(1) integrins. J Biol Chem. 2001;276:25005-25013.
21. Buschmann I, Schaper W. Arteriogenesis versus angiogenesis: two mechanisms of vessel growth. News Physiol Sci. 1999;14:121-125.
22. Buschmann I, Schaper W. The pathophysiology of the collateral circulation (arteriogenesis). J Pathol. 2000;190:388-342.
23. Rabinovitz I, Mercurio AM. The integrin alpha6beta4 functions in carcinoma cell migration on laminin-1 by mediating the formation and stabilization of action-containing motility structures. J Cell Biol. 1997;139:873-884.
24. Berditchevski F, Odintsova E. Characterization of integrin-tetraspanin adhesion complexes: role of tetraspanins in integrin signaling. J Cell Biol. 1999;146:477-492.
25. Fruman DA, Meyers RE, Cantley LC. Phosphoinositide kinases. Annu Rev Biochem. 1998;67: 481-507.
26. Hanks SK, Polte TR. Signaling through focal adhesion kinase. Bioessays. 1997;19:137-145.
27. Monahan PE, Samulski RJ. AAV: is clinical success in the horizon? Gene Ther. 2000;7:24-30.