Studies of the anticancer effect of calcineurin B

Immunopharmacology and Immunotoxicology

Volumn 27, Issue 2, 2005, Pages 199-210

  Jin, Feng Z ^a   Lian, Mu L ^a   Wang, Xia ^a   Wei, Qun ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

Author keywords

Anticancer; Calcineurin B; Immunocytes; Mechanism

Indexed keywords

CALCINEURIN; CALCINEURIN B; CALCIUM CALMODULIN STIMULATED PROTEIN PHOSPHATASE; CONCANAVALIN A; PHOSPHOPROTEIN PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CALCIUM BINDING; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENTIATION; ENZYME SUBUNIT; IMMUNE SYSTEM; LYMPHOCYTE; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PRIORITY JOURNAL; SOLID TUMOR; SPLEEN LYMPHOCYTE;

ANIMALS; ANTINEOPLASTIC AGENTS; CALCINEURIN; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CONCANAVALIN A; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; KILLER CELLS, NATURAL; LYMPHOCYTE SUBSETS; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED BALB C; PHAGOCYTOSIS; SARCOMA 180; SPLEEN;

MURINAE;

EID: 23244467561     PISSN: 08923973     EISSN: None     Source Type: Journal    
DOI: 10.1081/IPH-200067709     Document Type: Article

References (29)

1. Klee, C.B.; Crouch, T.H.; Krinks, M.H. Calcineurin: a calcium- and calmodulin-binding protein of the nervous system. Proc. Natl. Acad. Sci. U. S. A. 1979, 76, 6270-6273.
2. Klee, C.B.; Ren, H.; Wang, X. Regulation of the calmodulin-stimulated protein phosphatase, calcineurin. J. Biol. Chem. 1998, 273, 13367-13370.
3. Liu, J.; Farmer, J.D., Jr.; Lane, W.S.; Friedman, J.; Weissman, I.; Schreiber, S.L. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 1991, 66, 807-815.
4. Zoeteweij, J.P.; Moses, A.V.; Rinderknecht, A.S.; Davis, D.A.; Overwijk, W.W.; Yarchoan, R.; Orenstein, J.M.; Blauvelt, A. Targeted inhibition of calcineurin signaling blocks calcium-dependent reactivation of Kaposi sarcoma-associated herpesvirus. Blood 2001, 97, 2374-2380.
5. Paliogianni, F.; Hama, N.; Mavrothalassitis, G.J.; Thyphronitis, G.; Boumpas, D.T. Signal requirements for interleukin 4 promoter activation in human T cells. Cell. Immunol. 1996, 168 (1), 33-38.
6. Staruch, M.J.; Camacho, R.; Dumont, F.J. Distinctive calcineurin- dependent (FK506-sensitive) mechanisms regulate the production of the CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES vs. IL-2 and TNF-alpha by activated human T cells. Cell. Immunol. 1998, 190 (2), 121-131.
7. Haddy, A.; Swanson, S.K.; Born, T.L.; Rusnak, F. Inhibition of calcineurin by cyclosporin A-cyclophilin requires calcineurin B. FEBS Lett. 1992, 314 (1), 37-40.
8. Ueki, K.; Muramatsu, T.; Kincaid, R.L. Structure and expression of two isoforms of the murine calmodulin-dependent protein phosphatase regulatory subunit (calcineurin B). Biochem. Biophys. Res. Commun. 1992, 187, 537-543.
9. Kakalis, L.T.; Kennedy, M.; Sikkink, R.; Rusnak, F.; Armitage, I.M. Characterization of the calcium-binding sites of calcineurin B. FEBS Lett. 1995, 362, 55-58.
10. Wang, M.G.; Yi, H.; Guerini, D.; Klee, C.B.; McBride, O.W. Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21→q22 and 2p16→p15 respectively. Cytogenet. Cell Genet. 1996, 72, 236-241.
11. Jain, J.; McCaffrey, P.G.; Miner, Z.; Kerppola, T.K.; Lambert, J.N.; Verdine, G.L.; Curran, T.; Rao, A. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. Nature 1993, 365 (6444), 352-355.
12. Liu, J.; Zhu, J.K. A calcium sensor homolog required for plant salt tolerance. Science 1998, 280 (5317), 1943-1945.
13. Remillard, S.P.; Lai, E.Y.; Levy, Y.Y.; Fulton, C.A. calcineurin-B- encoding gene expressed during differentiation of the amoeboflagellate Naegleria gruberi contains two introns. Gene 1995, 154, 39-49.
14. Geiffith, J.P.; Kim, J.L.; Kim, E.E.; Sintchak, M.D.; Thomson, J.A.; Fitzgibbon, M.J.; Fleming, M.A.; Caron, P.R.; Hsiao, K.; Navia, M.A. X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex. Cell 1995, 82, 507-522.
15. Wei, Q.; Lian, M.L.; Jin, F.Z.; Zhang, N.; Yan, M.S. Studies of calcineurin B subunit from genetic engineering for use in medicine. Drug Dev. Res. 2002, 56, 40-43.
16. Wei, Q.; Lee, E.Y. Expression and reconstitution of calcineurin A and B subunits. Biochem. Mol. Biol. Int. 1997, 41, 169-177.
17. Fernandez-Urrusuno, R.; Fattal, E.; Rodrigues, J.M.; Feger, J.; Bedossa, P.; Couvreur, P. Effect of polymeric nanoparticle administration on the clearance activity of the mononuclear phagocyte system in mice. J. Biomed. Mater. Res. 1996, 31 (3), 401-408.
18. Ferrari, M.; Fornasiero, M.C.; Isetta, A.M. MTT colorimetric assay for testing macrophage cytotoxic activity in vitro. J. Immunol. Methods 1990, 131, 165-172.
19. Sladowski, D.; Steer, S.J.; Clothier, R.H.; Balls, M. An improved MTT assay. J. Immunol. Methods 1993, 157, 203-207.
20. Huttunen, K.; Ilonen, J. The determination of natural killer activity of human peripheral blood lymphocytes by measuring the DNA-synthesis of proliferating target cells (K 562 cell line). Acta Pathol. Microbiol. Immunol. Scand. C 1983, 91 (3), 197-201.
21. Davies, J.W.; Hall, T.C. Liquid scintillation counting methods for accurate assay of beta radioactivity in biological experiments. Anal. Biochem. 1969, 27 (1), 77-90.
22. Li, W.; Handschumacher, R.E. Identification of two calcineurin B-binding proteins: tubulin and heat shock protein 60. Biochim. Biophys. Acta 2002, 1599 (1-2), 72-81.
23. Kothe, G.D.; Free, S.J. Calcineurin subunit B is required for normal vegetative growth in Neurospora crassa. Fungal Genet. Biol. 1998, 23, 248-258.
24. Jackson, P.G.; Evans, S.R. Intraperitoneal macrophages and tumor immunity: a review. J. Surg. Oncol. 2000, 75 (2), 146-154.
25. Papamichail, M.; Perez, S.A.; Gritzapis, A.D.; Baxevanis, C.N. Natural killer lymphocytes: biology, development, and function. Cancer Immunol. Immunother. 2004, 53 (3), 176-186.
26. Yoon, T.J.; Yoo, Y.C.; Kang, T.B.; Song, S.K.; Lee, K.B.; Her, E.; Song, K.S.; Kim, J. B. Antitumor activity of the Korean mistletoe lectin is attributed to activation of macrophages and NK cells. Arch. Pharm. Res. 2003, 26 (10), 861-867.
27. Singh, N.; Singh, S.M.; Shrivastava, P. Immunomodulatory and antitumor actions of medicinal plant Tinospora cordifolia are mediated through activation of tumor-associated macrophages. Immunopharmacol. Immunotoxicol. 2004, 26 (1), 145-162.
28. Griffin, F.M.; Mullinax, P.J. High concentrations of bacterial lipopolysaccharide, but not microbial infection-induced inflammation, activate macrophage C3 receptors for phagocytosis. J. Immunol. 1990, 145 (2), 697-701.
29. Lane, T.E.; Wu-Hsieh, B.A.; Howard, D.H. Gamma interferon cooperates with lipopolysaccharide to activate mouse splenic macrophages to an antihistoplasma state. Infect. Immun. 1993, 61 (4), 1468-1473.