Effects of D-glucose concentration, D-fructose, and inhibitors of enzymes of the pentose phosphate pathway on the development and sex ratio of bovine blastocysts

Molecular Reproduction and Development

Volumn 72, Issue 2, 2005, Pages 201-207

  Kimura, Koji ^a,b   Spate, L D ^a   Green, M P ^a   Roberts, R Michael ^a  

^a UNIVERSITY OF MISSOURI   (United States)

^b NATIONAL INSTITUTE OF LIVESTOCK AND GRASSLAND SCIENCE   (Japan)

Author keywords

6 aminonicotinamide; Dehydroepiandrosterone; Embryo development; Glucose 6 phosphate dehydrogenase; NADPH; X chromosome inactivation

Indexed keywords

6 AMINONICOTINAMIDE; BRILLIANT CRESYL BLUE; DYE; ENZYME INHIBITOR; FRUCTOSE; GENE PRODUCT; GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; PRASTERONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BLASTOCYST; CATTLE; CHEMOSENSITIVITY; CULTURE MEDIUM; EMBRYO; EMBRYO CULTURE; EMBRYO DEATH; EMBRYO DEVELOPMENT; FEMALE; GENETIC TRANSCRIPTION; GLUCOSE METABOLISM; IN VITRO PRODUCED EMBRYO; IN VITRO STUDY; MALE; MORULA; NONHUMAN; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; SEX RATIO; X CHROMOSOME; ZYGOTE;

ANIMALS; BLASTOCYST; CATTLE; DEHYDROEPIANDROSTERONE; EMBRYO CULTURE TECHNIQUES; EMBRYONIC DEVELOPMENT; ENZYME INHIBITORS; FEMALE; FRUCTOSE; GLUCOSE; GLUCOSEPHOSPHATE DEHYDROGENASE; MALE; MORULA; OXAZINES; PENTOSE PHOSPHATE PATHWAY; SEX RATIO; STAINING AND LABELING;

BOVINAE;

EID: 23244460355     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.20342     Document Type: Article

References (65)

1. Augustin R, Pocar P, Navarrete-Santos A, Wrenzycki C, Gandolfi F, Niemann H, Fischer B. 2001. Glucose transporter expression is developmentally regulated in vitro derived bovine preimplantation embryos. Mol Reprod Dev 60:370-376.
2. Avery B, Madison V, Greve T. 1991. Sex and development in bovine in vitro fertilized embryos. Theriogenology 35:953-963.
3. Avery B, Jorgensen CB, Madison V, Greve T. 1992. Morphological development and sex of bovine in vitro-fertilized embryos. Mol Reprod Dev 32:256-270.
4. Babior B. 2000. Phagocytes and oxidative stress. Am J Med 109:33-44.
5. Biaglow JE, Ayene IS, Koch CJ, Donahue J, Stamato TD, Tuttle SW. 2000. G6PD deficient cells and the bioreduction of disulfides: effects of DHEA, GSH depletion and phenylarsine oxide. Biochem Biophys Res Commun 273:846-852.
6. Biggers JD. 1998. Reflections on the culture of the preimplantation embryo. Int J Dev Biol 42:879-884.
7. Canseco RS, Sparks AET, Page RL, Russell CG, Johnson JL, Velander WH, Pearson RE, Drohan WN, Gwazdauskas FC. 1994. Gene transfer efficiency during gestation and the influence of co-transfer of non-manipulated embryos on production of transgenic mice. Transgenic Res 3:20-25.
8. Carlson D, Black DL, Howe GR. 1970. Oviduct secretion in the cow. J Reprod Fertil 22:549-552.
9. Donnay I, Leese HJ. 1999. Embryos metabolism during the expansion of the bovine blastocyst. Mol Reprod Dev 53:171-178.
10. Downs SM, Dow MPD. 1991. Hypoxanthine-maintained two-cell block in mouse embryos: Dependence on glucose and effect of hypoxanthine phosphoribosyltransferase inhibitors. Biol Reprod 44:1025-1039.
11. Downs SM, Humpherson PG, Leese HJ. 1998. Meiotic induction in cumulus cell-enclosed mouse oocytes: Involvement of the pentose phosphate pathway. Biol Reprod 58:1084-1094.
12. Filosa S, Fico A, Paglialunga F, Balestrieri M, Crooke A, Verde P, Abrescia P, Bautista JM, Martini G. 2003. Failure to increase glucose consumption through the PPP results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress. Biochem J 370:935-943.
13. Foote RH. 1977. Sex ratios in dairy cattle under various conditions. Theriogenology 8:349-356.
14. Gardner DK, Lane M, Batt P. 1993. Uptake and metabolism of pyruvate and glucose by individual sheep preattachment embryos developed in vivo. Mol Reprod Dev 36:313-319.
15. Gardner DK, Lane M, Calderon I, Leeton J. 1996. Environment of the preimplantation human embryo in vivo: Metabolite analysis of oviduct and uterine fluids and metabolism of cumulus cells. Fertil Steril 65:349-353.
16. Gordon G, Mackow MC, Levy Hr. 1995. On the mechanism of interaction of steroids with human glucose 6-phosphate dehydrogenase. Arch Biochem Biophys 318:25-29.
17. Guerin P, El Mouatassim S, Menezo Y. 2001. Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surrounding. Hum Reprod Update 7:175-189.
18. Gutiérrez-Adán A, Oter M, Martinez-Madrid B, Pintado B, De La Fuente J. 2000. Differential expression of two genes located on the X chromosome between male and female in vitro-produced bovine embryos at the blastocyst stage. Mol Reprod Dev 55:146-151.
19. Gutiérrez-Adán A, Granados J, Pintado B, De la Fuente J. 2001. Influence of glucose on the sex ratio of bovine IVM/IVF embryos cultured in vitro. Reprod Fertil Dev 13:361-365.
20. Guyader-Joly C, Khatchadourian C, Menezo Y. 1996. Comparative glucose and fructose incorporation and conversion by in vitro produced bovine embryos. Zygote 4:85-91.
21. Harvey AJ, Kind KL, Thompson JG. 2002. REDOX regulation of early embryo development. Reprod 123:479-486.
22. Hernandez-Ledzma JJ, Sikes JD, Murphy CN, Watson AJ, Schultz GA, Roberts RM. 1992. Expression of bovine trophoblast Interferon in conceptuses derived by in vitro techniques. Biol Reprod 47:374-380.
23. Iwata H, Akamatsu S, Minami N, Yamada M. 1998. Effects of antioxidants on the development of bovine IVM/IVF embryos in various concentrations of glucose. Theriogenology 50:365-375.
24. Iwata H, Akamatsu S, Minami N, Yamada M. 1999. Allopurinol, an inhibitor of xanthine oxidase, improves the development of IVM/IVF bovine embryos (>4 cell) in vitro under certain culture conditions. Theriogenology 51:613-622.
25. Iwata H, Kimura K, Hashimoto S, Ohta M, Tominaga K, Minami N. 2002. Role of G6PD activity on sex ratio and developmental competence of bovine embryos under oxidative stress. J Reprod Dev 48:447-453.
26. Kabashima T, Kawaguchi T, Wadzinski BE, Uyeda K. 2003. Xylulose 5-phosphate mediates glucose-induced lipogenesis by xylulose 5-phosphate-activated protein phosphatase in rat liver. Proc Natl Acad Sci USA 100:5107-5112.
27. Kenny DA, Humpherson PG, Leese HJ, Morris DG, Tomos AD, Diskin MG, Sreenan JM. 2002. Effect of elevated systematic concentrations of ammonia and urea on the metabolite and ionic composition of oviductal fluid in cattle. Biol Reprod 66:1797-1804.
28. Khurana NK, Niemann H. 2000. Energy metabolism in preimplantation bovine embryos derived in vitro or in vivo. Biol Reprod 62:847-856.
29. Kim JH, Niwa K, Lim JM, Okuda K. 1993. Effects of phosphate, energy substrates, and amino acids on development of in vitro-matured, in vitro-fertilized bovine oocytes in a chemically defined, protein-free culture medium. Biol Reprod 48:132-135.
30. Kimura K, Spate LD, Green MP, Roberts RM. 2004. Effects of oxidative stress and inhibitions of the pentose phosphate pathway on sexually dimorphic production of IFN-τ by bovine blastocysts. Mol Reprod Dev 68:88-95.
31. Kohler E, Barrach H, Neubert D. 1970. Inhibition of NADP dependent oxidoreductases by the 6-aminonicotinamide analogue of NADP. FEES Lett 6:225-228.
32. Kubisch HM, Larson MA, Roberts RM. 1998. Relationship between age of blastocyst formation and interferon-tau secretion by in vitro-derived bovine embryos, Mol Reprod Dev 49:254-260.
33. Kwun J, Chang K, Lim J, Lee E, Lee B, Kang S, Hwang W. 2003. Effects of exogenous hexoses on bovine in vitro fertilized and cloned embryo development: Improved blastocyst formation after glucose replacement with fructose in a serum-free culture medium. Mol Reprod Dev 65:167-174.
34. Larson MA, Kimura K, Kubisch HM, Roberts RM. 2001. Sexual dimorphism among bovine embryos in their ability to make the transition to expanded blastocyst and in the expression of the signaling molecule IFN-tau. Proc Natl Acad Sci USA 98:9677-9682.
35. Lee AJ, Twardock AR, Bubar RH, Hall JE, Davis CL. 1978. Blood metabolic profiles: Their use and relation to nutritional status of dairy cows. J Dairy Sci 61:1652-1670.
36. Leese HJ, Tay JI, Reischl J, Downing SJ. 2001. Formation of Fallopian tubal fluid: Role of a neglected epithelium. Reproduction 121:339-346.
37. Loutradis D, John D, Kissling AA. 1987. Hypoxanthine causes a 2-cell block in random-bred mouse embryos. Biol Reprod 37:311-316.
38. McDonald LE. 1980. Pancreas hormones: Insulin and glucagons. In: Veterinary endocrinology and reproduction. Philadelphia, PA: Lea & Febiger. pp 131-147.
39. Parrish JJ, Susko-Parrish JL, First NL. 1989. Capacitation of bovine sperm by heparin: Inhibitory effect of glucose and role of intracellular pH. Biol Reprod 41:683-699.
40. Peippo J, Kurkilahti M, Bredbacka P. 2001. Developmental kinetics if in vitro produced bovine embryos: The effect of sex, glucose and exposure to time-lapse environment. Zygote 9:105-113.
41. Peippo J, Farazmand A, Kurkilahti M, Markkula M, Basrur PK, King WA. 2002. Sex-chromosome linked gene expression in in-vitro produced bovine embryos. Mol Hum Reprod 8:923-929.
42. Peura T, Hyttinen M, Turunen M, Jane J. 1991. A reliable sex determination assay for bovine preimplantation embryos using the polymerase chain reaction. Theriogenology 35:545-556.
43. Pinyopummintr T, Bavister BD. 1996a. Effects of amino acids on development in vitro of cleavage-stage bovine embryos into blastocysts. Reprod Fertil Dev 8:835-841.
44. Pinyopummintr T, Bavister BD. 1996b. Energy substrate requirements for in vitro development of early cleavage-stage bovine embryos. Mol Reprod Dev 44:193-199.
45. Pujol M, López-Bèjar M, Paramio MT. 2004. Developmental competence of heifer oocytes selected using the brilliant cresyl blue (BCB) test. Theriogenology 61:735-744.
46. Rieger D. 1992. Relationships between energy metabolism and development of early mammalian. Theriogenology 37:75-93.
47. Rieger D, Loskutoff NM, Betteridge KJ. 1992a. Developmentally related changes in the uptake and metabolism of glucose, glutamine and pyruvate by cattle embryos produced in vitro. Reprod Fertil Dev 4:547-557.
48. Rieger D, Loskutoff NM, Betteridge KJ. 1992b. Developmentally related changes in the metabolism of glucose and glutamine by cattle embryos produced and co-cultured in vitro. J Reprod Fertil 95:585-595.
49. Rodriguez-Gonzalez E, Lopez-Bejar M, Velilla E, Paramio MT. 2002. Selection of prepubertal goat oocytes using the brilliant cresyl blue test. Theriogenology 57:1397-1409.
50. Rieger D, McGowan LT, Cox SF, Pugh PA, Thompson JG. 2002. Effect of 2,4-dinitrophenol on the energy metabolism of cattle embryos produced by in vitro fertilization and culture. Reprod Fertil Dev 14:339-343.
51. Salvemini F, Franze A, lervolino A, Filosa S, Salzano S, Ursini MV. 1999. Enhanced glutathione levels and oxidoresistance mediated by increased glucose-6-phosphate dehydrogenase expression. J Biol Chem 274:2750-2757.
52. Saran M. 2003. To what end does nature produce Superoxide? NADPH oxidase autocrine modifier of membrane phospholipids generating paralipid messengers. Free Radic Res 37:1045-1059.
53. Schini SA, Bavister BD. 1988. Two-cell block to development of cultured hamster embryos is caused by phosphate and glucose. Biol Reprod 39:1183-1192.
54. Scott L, Whittingham DG. 2002. Role of facultative glucose uptake in the glucose-inorganic phosphate-mediated retardation and inhibition of development in different strains of mouse embryos. Reproduction 123:691-700.
55. Seshagiri PB, Bavister BD. 1989. Glucose inhibits development of hamster 8-cell embryos in vitro. Biol Reprod 40:599-606,
56. Seshagiri PB, Bavister BD. 1991. Glucose and phosphate inhibit respiration and oxidative metabolism in cultured hamster eight-cell embryos: Evidence for the "crabtree effect". Mol Reprod Dev 30:105-111.
57. Shantz LM, Talalay P, Gordon GB. 1989. Mechanism of inhibition of growth of 3T3-L1 fibroblasts and their differentiation to adipocytes by dehydroepiandrosterone and related steroids: role of glucose-6-phosphate dehydrogenase. Proc Natl Acad Sci USA 86:3852-3856.
58. Suga T, Masaki J. 1973. Studies on the secretions of the cow 6. Sugar and polyol constituents in the luminal fluid of the bovine uterus. Jpn J Anim Reprod 18:143-147.
59. Takahashi T, First NL. 1992. In vitro development of bovine one-cell embryos: Influence of glucose, lactate, pyruvate, amino acids and vitamins. Theriogenology 37:963-978.
60. Thompson JG, Simpson AC, Pugh PA, Wright RW Jr, Tervit HR. 1991. Glucose utilization by sheep embryos derived in vivo and in vitro. Reprod Fertil Dev 3:571-576.
61. Thompson JG, Simpson AC, Pugh PA, Tervit HR. 1992. Requirement for glucose during in vitro culture of sheep preimplantation embryos. Mol Reprod Dev 31:253-257.
62. Thompson JG, Partridge RJ, Houghton FD, Cox CI, Leese HJ. 1996. Oxygen uptake and carbohydrate metabolism by in vitro derived bovine embryos. J Reprod Fertil 106:299-306.
63. Tiffin GJ, Rieger D, Betteridge KJ, Yadav BR, King WA. 1991. Glucose and glutamine metabolism in pre-attachment cattle embryos in relation to sex and stage of development. J Reprod Fertil 93:125-132.
64. Walker SK, Hill JL, Kleemann DO, Nancarrow CD. 1996. Development of ovine embryos in synthetic oviductal fluid containing amino acids at oviductal fluid concentrations. Biol Reprod 55:703-708.
65. Xu KP, Yadav BR, King WA, Betteridge KJ. 1992. Sex-related differences in developmental rates of bovine embryos produced and cultured in vitro. Mol Reprod Dev 31:249-252.