Global model for optimizing crossflow microfiltration and ultrafiltration processes: A new predictive and design tool

Biotechnology Progress

Volumn 21, Issue 4, 2005, Pages 1013-1025

  Baruah, Gautam Lal ^a,b   Venkiteshwaran, Adith ^a   Belfort, Georges ^a  

^a Rensselaer Polytechnic Institute   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHMS; ELECTROSTATICS; HEMOGLOBIN; MATHEMATICAL MODELS; MEMBRANES; MICROFILTRATION; OPTIMIZATION;

CROSSFLOW MICROFILTRATION; IONIC ENVIRONMENT; MEMBRANE PROPERTIES; POLYDISPERSITY;

ULTRAFILTRATION;

BOVINE SERUM ALBUMIN; HEMOGLOBIN; IMMUNOGLOBULIN G; PROTEIN;

ALGORITHM; ANIMAL; ARTIFICIAL MEMBRANE; CHEMISTRY; ELECTRICITY; GOAT; ISOLATION AND PURIFICATION; METHODOLOGY; MILK; OSMOLARITY; PRESSURE; REPRODUCIBILITY; REVIEW; THEORETICAL MODEL; ULTRAFILTRATION;

ALGORITHMS; ANIMALS; ELECTROSTATICS; GOATS; HEMOGLOBINS; IMMUNOGLOBULIN G; MEMBRANES, ARTIFICIAL; MILK; MODELS, THEORETICAL; OSMOLAR CONCENTRATION; PRESSURE; PROTEINS; REPRODUCIBILITY OF RESULTS; SERUM ALBUMIN, BOVINE; ULTRAFILTRATION;

BOVINAE; CAPRA HIRCUS;

EID: 23244443902     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp050184r     Document Type: Review

References (44)

1. van Reis, R.; Frautschy, L. N.; Goodrich, E. M.; Saksena, S.; Kuriyel, R.; Simpson, C. M.; Pearl, S.; Zydney, A. L. High performance tangential flow filtration. Biotechnol. Bioeng. 1997, 56, 71-82.
2. Cherkasov, A. N.; Polotsky, A. E. The resolving power of Ultrafiltration. J. Membr. Sci. 1996, 110, 79-82.
3. DiLeo, A. J.; Allegrezza, A. E.; Builder, S. E. High-resolution removal of virus from protein solutions using a membrane of unique structure. Bio/Technology 1992, 10, 182-188.
4. Muller, A.; Daufin, G.; Chaufer, B. Ultrafiltration modes of operation for the separation of α-lactalbumin from acid casein whey. J. Membr. Sci. 1999, 153, 9-21.
5. Rabiller-Baudry, M.; Chaufer, B.; Aimar, P.; Bariou, B.; Lucas, D. Application of a convection-diffusion-electrophoretic migration model to ultrafiltration of lysozyme at different pH values and ionic strengths. J. Membr. Sci. 2000, 179, 163-174.
6. Nystrom, M.; Aimar, P.; Luque, S.; Kulovarra, M.; Metsamuuronen, S. Fractionation of model proteins using their physicochemical properties. Colloids Surf. 1998, 138, 185-205.
7. Saksena, S.; Zydney, A. L. Effect of solution pH and ionic strength on the separation of albumin from immunoglobulin-(IgG) by selective filtration. Biotechnol. Bioeng. 1994, 43, 960-968.
8. van Reis, R.; Saksena, S. M. Optimization diagram for membrane separations. J. Membr. Sci. 1997, 129, 19-29.
9. Baruah, G. L.; Belfort, G. A predictive aggregate transport model for microfiltration of combined macromolecular solutions and poly-disperse suspensions: model development. Biotechnol. Prog. 2003, 19, 1524-1532.
10. Baruah, G. L.; Couto, D.; Belfort, G. A predictive aggregate transport model for microfiltration of combined macromolecular solutions and poly-disperses suspensions: testing model with transgenic goat milk. Biotechnol. Prog. 2003, 19, 1533-1540.
11. Samuelsson, G.; Huisman, I. H.; Tragardh, G.; Paulsson, M. Predicting limiting permeation flux of skim milk in cross-flow microfiltration. J. Membr. Sci. 1997, 129, 277-281.
12. Dharmappa, H. B.; Verink, J.; Aim, R. B.; Yamamoto, K.; Vigneswaran, S. A comprehensive model for cross-flow filtration incorporating polydispersity of the influent. J. Membr. Sci. 1992, 65, 173-185.
13. Baruah, G. L.; Belfort, G. Optimized recovery of monoclonal antibodies from transgenic goat milk by microfiltration. Biotechnol. Bioeng. 2004, 87, 274-285.
14. Belfort, G. Coiled membrane filtration system. U.S. Patent RE 37, 759, 2002.
15. Belfort, G.; Davis, R. H.; Zydney, A. L. The behavior of suspensions and macromolecular solutions in crossflow microfiltration. J. Membr. Sci. 1994, 96, 1-58.
16. Zeman, L. J.; Zydney, A. L. Microfiltration and Ultrafiltration Principles and Applications; Marcel Dekker: New York, 1996.
17. Pujar, S. N.; Zydney, A. L. Electrostatic effects on protein partitioning in size- exclusion chromatography and membrane ultrafiltration. J. Chromatogr. A 1998, 796, 229-238.
18. Smith, F. G.; Deen, W. M. Electrostatic double-layer interactions for spherical colloids in cylindrical pores. J. Coll. Interface Sci. 1980, 78, 444-465.
19. Bhattacharjee, S.; Sharma, A. Lifshitz-van der Waals energy of spherical particles in cylindrical pores. J. Colloid Interface Sci. 1995, 171, 288-296.
20. Winzeler, H. B.; Belfort, G. Enhanced performance for pressure-driven membrane processes: The argument for fluid instabilities. J. Membr. Sci. 1993, 80, 35-47.
21. Luque, S.; Mallubhotla, H.; Gelhert, G.; Kuriyel, R.; Dzengeleski, S.; Pearl, S.; Belfort, G. S. A new, coiled hollow fiber module design for enhanced microfiltration performance. Biotechnol. Bioeng. 1999, 65, 247-257.
22. Torre, J. C.; Huertas, M. L.; Carrasco, B. Calculation of hydrodynamic properties of globular proteins from their atomic level structure. Biophys. J. 2000, 78, 719-730.
23. Dupont, M. A.; Focault, G.; Vacher, M.; Devaux, P.; Cribier, S. Translational diffusion of globular ptoteins in the cytoplasm of cultured muscle cells. Biophys. J. 2000, 78, 901-907.
24. Zydney, A. L.; Mehta, A. Permeability and selectivity analysis for ultrafiltration membranes. J. Membr. Sci. 2005, 249, 245-249.
25. Negin, R. S.; Carbeck, J. D. Measurement of electrostatic interactions in protein folding with the use of protein charge ladders. J. Am. Chem. Soc. 2001, 124, 2911-2916.
26. Giddings, J. C.; Kucera, E.; Russel, C. P.; Myers, M. N. Statistical theory for the equilibrium distribution of rigid molecules in inert porous networks. J. Phys. Chem. 1968, 72, 4397-4408.
27. Opong, W. S.; Zydney, A. L. Diffusive and convective transport through asymmetric membranes. AIChE J. 1991, 37, 1497-1510.
28. Mochizuki, S.; Zydney, A. L. Dextran transport through asymmetric ultrafiltration membranes: Comparison with hydrodynamic models. J. Membr. Sci. 1992, 68, 21-41.
29. Langsdorf, L. J.; Zydney, A. L. Diffusive and convective transport through through hemodialysis membranes: Comparison with hydrodynamic predictions. J. Biomed. Mater. Res. 1994, 28, 573-582.
30. Al-Akoum, O.; Mercier-Bonin, M.; Ding, L.; Fonade, C.; Aptel, P.; Jaffrin, M. Hydrodynamic characterization and comparison of three particular systems used for flux enhancement: Application to crossflow filtration of a yeast suspension. ICOM oral 2002, 573.
31. Po, H. N.; Senozan, N. M. The Henderson-Hasselbach equation: its history and limitations J. Chemm. Educ. 2001, 78, 1499-1503.
32. DelPhi Poisson-Boltzmann Electrostatics Simulation Engine; Accelrys: San Diego, Ca.
33. Voet, D.; Voet, J. G.; Pratt, C. Fundamentals of Biochemistry; Wiley: New York, 1999.
34. Yoon, B. J.; Lenhoff, A. M. Computation of the electrostatic interaction energy between a protein and a charged surface. J. Phys. Chem. 1992, 96, 3130-3134.
35. Dodds, J. A. The porosity and contact points in multicomponent random sphere packings calculated by a simple statistical geometric model. J. Colloid Interface Sci. 1980, 77, 317-327.
36. Farris, R. J. Prediction of the viscosity of multimodal suspensions from unimodal viscosity data. Trans. Soc. Rheol. 1968, 12, 281-301.
37. Probstein, R. F.; Sengun, M. Z.; Tseng, T. C. Bimodal model of concentrated suspension viscosity for distributed particle sizes. J. Rheol. 1994, 38, 811-829.
38. Gondret, P.; Petit, L. Dynamic viscosity of macroscopic suspensions of bimodal sized solid spheres. J. Rheol. 1997, 41, 1261-1274.
39. Forman, S.; DeBernardez, E. R.; Feldberg, R. S.; Swartz, R. W. Cross-flow filtration of inclusion bodies from soluble proteins in recombinant e-coli cell lysate. J. Membr. Sci. 1990, 48, 263-279.
40. Bailey, S. M.; Meagher, M. M. Cross-flow microfiltration of recombinant e-coli cell lysates after high-pressure homogenization. Biotechnol. Bioeng. 1997, 56, 304-310.
41. Raymond, H. C.; van Eijndhoven; Saksena, S.; Zydney, A. L. Protein fractionation using electrostatic interactions in membrane filtration. Biotechnol. Bioeng. 1995, 48, 406-414.
42. Saksena, S.; Zydney, A. L. Effect of solution pH and ionic strength on the separation of albumin from immunoglobulins by selective filtration. Biotechnol. Bioeng. 1994, 43, 960-968.
43. Le Berre, O.; Daufin, G. Microfiltration (0.1 μm) of milk: effect of protein size and charge. J. Dairy Res. 1998, 65, 443-455.
44. Baker, R. J.; Fane, A. G.; Fell, C. J. D.; Yoo, B. H. Factors affecting flux in crossflow filtration. Desalination 1985, 53, 81-93.