Ischemia-reperfusion causes exudative detachment of the rabbit retina

Investigative Ophthalmology and Visual Science

Volumn 46, Issue 7, 2005, Pages 2592-2600

  Uckermann, Ortrud ^a,b   Uhlmann, Susann ^a   Pannicke, Thomas ^a   Franche, Mike ^a   Gamsalijew, Ruslan ^a   Makarov, Felix ^c   Ulbricht, Elke ^a   Wiedemann, Peter ^a   Reichenbach, Andreas ^a   Osborne, Neville N ^d   Bringmann, Andreas ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY HOSPITAL LEIPZIG   (Germany)

^c PAVLOV INSTITUTE OF PHYSIOLOGY   (Russian Federation)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; LECTIN; POTASSIUM; TRIAMCINOLONE ACETONIDE; CALCIUM CHANNEL; GLUCOCORTICOID; POTASSIUM CHANNEL; PURINE P2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; GLIOSIS; HYPERTROPHY; IMMUNOCOMPETENT CELL; INTRAOCULAR PRESSURE; MICROGLIA; MUELLER CELL; NERVE FIBER; NONHUMAN; PHOTORECEPTOR CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; REPERFUSION INJURY; RETINA ISCHEMIA; ANIMAL; CELL COUNT; CELL MEMBRANE POTENTIAL; DISEASE MODEL; EXUDATE; FEMALE; MALE; METABOLISM; PATHOLOGY; PHOTORECEPTOR; RABBIT; RETINA BLOOD VESSEL; RETINA DETACHMENT;

ANIMALS; CALCIUM CHANNELS; CELL COUNT; DISEASE MODELS, ANIMAL; EXUDATES AND TRANSUDATES; FEMALE; GLIOSIS; GLUCOCORTICOIDS; MALE; MEMBRANE POTENTIALS; MICROGLIA; NERVE FIBERS; PHOTORECEPTORS, VERTEBRATE; PIGMENT EPITHELIUM OF EYE; POTASSIUM CHANNELS; RABBITS; RECEPTORS, PURINERGIC P2; REPERFUSION INJURY; RETINAL DETACHMENT; RETINAL VESSELS; TRIAMCINOLONE ACETONIDE;

EID: 23244433875     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.04-1402     Document Type: Article

References (55)

1. Osborne NN, Casson RJ, Wood JP, Chidlow G, Graham M, Melena J. Retinal ischemia: mechanisms of damage and potential therapeutic strategies. Prog Retin Eye Res. 2004;23:91-147.
2. Block F, Schwarz M. Effects of antioxidants on ischemic retinal dysfunction. Exp Eye Res. 1997;64:559-564.
3. Muller A, Pietri S, Villain M, Frejaville C, Bonne C, Culcas M. Free radicals in rabbit retina under ocular hyperpressure and functional consequences. Exp Eye Res. 1997;64:637-643.
4. Szabo ME, Droy-Lefaix MT, Doly M. Direct measurement of free radicals in ischemic/reperfused diabetic rat retina. Clin Neurosci. 1997;4:240-245.
5. Lucas DR, Newhouse JP. The toxic effect of sodium L-glutamate on the inner layers of the retina. Arch Ophthalmol. 1957;58:193-201.
6. Louzada-Junior P, Dias JJ, Santos WF, Lachat JJ, Bradford HF, Coutinho-Netto J. Glutamate release in experimental ischaemia of the retina: an approach using microdialysis. J Neurochem. 1992; 59:358-363.
7. Kuroiwa T, Ting P, Martinez H, Klatzo I. The biphasic opening of the blood-brain barrier to proteins following temporary middle cerebral artery occlusion. Acta Neuropathol (Bert). 1985;68:122-129.
8. Belayev L, Busto R, Zhao W, Ginsberg MD. Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats. Brain Res. 1996;739:88-96.
9. Rosenbaum DM, Rosenbaum PS, Gupta H, et al. The role of the p53 protein in the selective vulnerability of the inner retina to transient ischemia. Invest Ophthalmol Vis Sci. 1998;39:2132-2139.
10. Shibuki H, Katai N, Kuroiwa S, Kurokawa T, Yodoi J, Yoshimura N. Protective effect of adult T-cell leukemia-derived factor on retinal ischemia-reperfusion injury in the rat. Invest Ophthalmol Vis Sci. 1998;39:1470-1477.
11. Smith GG, Baird CD. Survival time of retinal cells when deprived of their blood supply by increased intraocular pressure. Am J Ophthalmol. 1952;35:133-136.
12. Hughes WF. Quantification of ischemic damage in the rat retina. Exp Eye Res. 1991;53:573-582.
13. Buchi ER, Suivaizdis I, Fu J. Pressure-induced retinal ischemia in rats: an experimental model for quantitative study. Ophthalmologica. 1991;203:138-147.
14. Larsen AK, Osborne NN. Involvement of adenosine in retinal ischemia. Invest Ophthalmol Vis Sci. 1996;37:2603-2611.
15. Rosenbaum DM, Rosenbaum PS, Singh M, et al. Functional and morphologic comparison of two methods to produce transient retinal ischemia in the rat. J Neuroophthalmol. 2001;21:62-68.
16. Ju WK, Kim KY, Park SJ, et al. Nitric oxide is involved in sustained and delayed cell death of rat retina following transient ischemia. Brain Res. 2000;881:231-236.
17. Johnson NF. Effects of acute ischaemia on the structure of the rabbit retina. Trans Ophthalmol Soc UK. 1974;94:394-405.
18. Johnson NF. Retinal glycogen content during ischaemia. Graefes Arch Clin Exp Ophthalmol. 1977;203:271-282.
19. Parrish R, Gass JD, Anderson DR. Outer retina ischemic infarction-a newly recognized complication of cataract extraction and closed vitrectomy. Part 2. An animal model. Ophthalmology. 1982; 89:1472-1477.
20. Brandstätter JH, Koulen P, Wässle H. Diversity of glutamate receptors in the mammalian retina. Vision Res. 1998;38:1385-1397.
21. Hayashi A, Koroma BM, Imai K, de Juan E Jr. Increase of protein tyrosine phosphorylation in rat retina after ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 1996;37:2146-2156.
22. Neufeld AH, Kawai S, Das S, et al. Loss of retinal ganglion cells following retinal ischemia: trie role of inducible nitric oxide synthase. Exp Eye Res. 2002;75:521-528.
23. Neufeld AH. Nitric oxide: a potential mediator of retinal ganglion cell damage in glaucoma. Surv Ophthalmol. 1999;43:S129-S135.
24. Wen R, Song Y, Cheng T, et al. Injury-induced upregulation of bFGF and CNTF mRNAs in the rat retina. J Neurosci. 1995;15: 7377-7385.
25. Harada T, Harada C, Nakayama N, et al. Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration. Neuron. 2000;26:533-541.
26. Bringmann A, Francke M, Reichenbach A. Müller cells in retinopathies. In: Hertz L, ed. Non-neuronal Cells in the Nervous System: Function and Dysfunction. Part III: Pathological Conditions. Amsterdam, Elsevier; 2004:1117-1132.
27. Yuan L, Neufeld AH. Tumor necrosis factor-alpha: a potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head. Glia. 2000;32:42-50.
28. Tezel G, Wax MB. Increased production of tumor necrosis factor-alpha by glial cells exposed to simulated ischemia or elevated hydrostatic pressure induces apoptosis in cocultured retinal ganglion cells. J Neurosci. 2000;20:8693-8700.
29. Martin KR, Levkovitch-Verbin H, Valenta D, Baumrind L, Pease ME, Quigley HA. Retinal glutamate transporter changes in experimental glaucoma and after optic nerve transection in the rat. Invest Ophthalmol Vis Sci. 2002;43:2236-2243.
30. Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 1996;19:312-318.
31. Streit WJ. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia. 2002;40:133-139.
32. Banati RB, Gehrmann J, Schubert P, Kreutzberg GW. Cytotoxicity of microglia. Glia. 1993;7:111-118.
33. Hopkins SJ, Rothwell NJ. Cytokines and the nervous system. I. Expression and recognition. Trends Neurosci. 1995;18:83-88.
34. Frade JM, Barde YA. Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron. 1998;20:35-41.
35. Roque RS, Rosales AA, Jingjing L, Agarwal N, Al-Ubaidi MR. Retina-derived microglial cells induce photoreceptor cell death in vitro. Brain Res. 1999;836:110-119.
36. Thanos S, Mey J, Wild M. Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro. J Neurosci. 1993;13:455-466.
37. Harada T, Harada C, Kohsaka S, et al. Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration. J Neurosci. 2002;22:9228-9236.
38. Newman EA, Reichenbach A. The Müller cell: a functional element of the retina. Trends Neurosci. 1996;19:307-312.
39. Francke M, Pannicke T, Biedermann B, et al. Loss of inwardly rectifying potassium currents by human retinal glial cells in diseases of the eye. Glia. 1997;20:210-218.
40. Francke M, Faude F, Pannicke T, et al. Electrophysiology of rabbit Müller (glial) cells in experimental retinal detachment and PVR. Invest Ophthalmol Vis Sci. 2001;42:1072-1079.
41. Pannicke T, Iandiev I, Uckermann O, et al. A potassium channel-linked mechanism of glial cell swelling in the postischemic retina. Mol Cell Neurosci. 2004;26:493-502.
42. Francke M, Weick M, Pannicke T, et al. Up-regulation of extracellular ATP-induced Müller cell responses in a dispase model of proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 2002; 43:870-881.
43. Uhlmann S, Bringmann A, Uckermann O, et al. Early glial cell reactivity in experimental retinal detachment: effect of suramin. Invest Ophthalmol Vis Sci. 2003;44:4114-4122.
44. Uckermann O, Grosche J, Reichenbach A, Bringmann A. ATP-evoked calcium responses of radial glial (Müller) cells in the postnatal rabbit retina. J Neurosci Res. 2002;70:209-218.
45. Reichenbach A, Wohlrab F. Morphometric parameters of Muller (glial) cells dependent on their topographic localization in the nonmyelinated part of the rabbit retina: a consideration of functional aspects of radial glia. J Neurocytol. 1986;15:451-459.
46. Newman EA. Distribution of potassium conductance in mammalian Müller (glial) cells: a comparative study. J Neurosci. 1987;7: 2423-2432.
47. Osborne NN, Wood JPM, Cupido A, Melena J, Chidlow G. Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity. Invest Ophthalmol Vis Sci. 2002;43:1456-1464.
48. Faude F, Francke M, Makarov F, et al. Experimental retinal detachment causes widespread and multilayered degeneration in rabbit retina. J Neurocytol. 2001;30:379-390.
49. AB-2/Kir4.1, on mammalian retinal Müller cell membrane: their regulation by insulin and laminin signals. J Neurosci. 1997;17:7725-7735.
50. Kofuji P, Biedermann B, Siddharthan V, et al. Kir potassium channel subunit expression in retinal glial cells: implications for spatial potassium buffering. Glia. 2002;39:292-303.
51. Ip M, Kahana A, Altaweel M. Treatment of central retinal vein occlusion with triamcinolone acetonide: an optical coherence tomography study. Semin Ophthalmol. 2003;18:67-73.
52. Massin P, Audren F, Haouchine B, et al. Intravitreal triamcinolone acetonide for diabetic diffuse macular edema: preliminary results of a prospective controlled trial. Ophthalmology. 2004:111:218-224.
53. Ando N, Sen HA, Berkowitz BA, Wilson CA, de Juan E Jr. Localization and quantification of blood-retinal barrier breakdown in experimental proliferative vitreoretinopathy. Arch Ophthalmol. 1994;112:117-122.
54. Sakamoto T, Miyazaki M, Hisatomi T, et al. Triamcinolone-assisted pars plana vitrectomy improves the surgical procedures and decreases the postoperative blood-ocular barrier breakdown. Graefes Arch Clin Exp Ophthalmol. 2002;240:423-429.
55. Penfold PL, Wen L, Madigan MC, Gillies MC, King NJ, Provis JM. Triamcinolone acetonide modulates permeability and intercellular adhesion molecule-1 (ICAM-1) expression of the ECV304 cell line: implications for macular degeneration. Clin Exp Immunol. 2000; 121:458-465.