Effects of antioxidants on ischemic retinal dysfunction

Experimental Eye Research

Volumn 64, Issue 4, 1997, Pages 559-564

  Block, F ^a,b   Schwarz, M ^b  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Antioxidants; Electroretinogram; Rat; Retinal ischemia

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; THIOCTIC ACID;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTRORETINOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA BLOOD FLOW; RETINA ISCHEMIA;

EID: 0031126568     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1996.0244     Document Type: Article

References (31)

1. Amagasa, M., Mizoi, K., Yoshimoto, T. and Suzuki, J. (1988). Protective effect of various agents against ischemic neuronal damage in guinea pig hippocampal neurons studied in vitro. Neurol. Surg. 16, 1363-71.
2. Bast, A. and Haenen, R. M. M. (1988). Interplay between lipoic acid and glutathione in the protection against microsomal lipid peroxidation. Biochem. Biophys. Acta 963, 558-61.
3. Benveniste, H., Drejer, J., Schousboe, A. and Diemer, N. H. (1984). Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43, 369-74.
4. Blauth, C., Smith, P., Newman, S., Arnold, J., Siddons, F., Harrison, M. J., Treasure, T., Klinger, L. and Taylor, K. M. (1989). Retinal microembolism and neuropsychological deficit following clinical cardiopulmonary bypass: comparison of a membrane and a bubble oxygenator. Eur. J. Card. Surg. 3, 135-8.
5. Block, F., Pergande, G. and Schwarz, M. (1994). Flupirtine protects against ischemic retinal dysfunction in rats. Neuroreport 5, 2630-2.
6. Block, F., Schwarz, M. and Sontag, K.-H. (1992). Retinal ischemia induced by occlusion of both common carotid arteries in rats as demonstrated by electroretinography. Neurosci. Lett. 144, 124-6.
7. Block, F. and Sontag, K.-H. (1994). Differential effects of transient occlusion of common carotid arteries in normotensive rats on the somatosensory and visual system. Brain Res. Bull. 33, 589-93.
8. Bresnick, G. H. (1989). Excitotoxins : a possible new mechanism for the pathogenesis of ischemic retinal damage. Arch. Ophthalmol. 107, 339-41.
9. Brunette, J. R., Olivier, P., Blondeau, P., Zaharia, M. and Lafond, G. (1986). Electroretinographic recovery from controlled total ischemia. Can. J. Ophthalmol. 21, 13-8.
10. Busse, E., Zimmer, G., Schopohl, B. and Kornhuber, B. (1992). Influence of α-lipoic acid on intracellular glutathione in vitro and in vivo. Arzneim-Forsch./Drug Res. 42, 829-31.
11. Coleman, K., Fitzgerald, D., Eustace, P. and Bouchier-Hayes, D. (1990). Electroretinography, retinal ischemia and carotid artery disease. Eur. J. Vasc. Surg. 4, 569-73.
12. Delbarre, G., Delbarre, B., Calinon, F. and Ferger, A. (1991). Accumulation of amino acids and hydroxyl free radicals in brain and retina of gerbil after transient ischemia. J. Ocular. Pharmacol. 7, 147-55.
13. Dugan, J. D. and Green, W. R. (1991). Ophthalmic manifestation of carotid occlusive disease. Eye 5, 226-38.
14. Ehrenthal, W. and Prellwitz, W. (1986). Biochemie und Pharmakologie der Liponsäure. In Interdisziplinäre Bestandsaufnahme der Polyneuropathien. (Eds Neundörfer, B. and Sailer, D.) Erlangen: Perimed-Fachbuchverlag, pp. 154-66.
15. 14C-tocopheryl acetate in the rat following oral administration. Arch. Int. Pharmaco. 250, 4-17.
16. Gryglewski, R. J., Palmer, R. M. J. and Moncada, S. (1986). Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320, 454-6.
17. Halliwell, B. and Gutteridge, J. M. C. (1985). Oxygen radicals and the nervous system. Trends Neurosci. 8, 22-6.
18. Hara, H., Kato, H. and Kogure, K. (1990). Protective effect of α-tocopherol on ischemic neuronal damage in the gerbil hippocampus. Brain Res. 510, 335-8.
19. Holm, S. (1979). A simple sequentially rejective multiple test procedure. Scand. J. Stat. 6, 65-70.
20. Miller, R. F. and Dowling, J. E. (1970). Intracellular responses of the Müller (glial) cells of mudpuppy retina : their relation to b-wave of the electroretinogram. J. Neurophysiol. 33, 323-41.
21. Nayak, M. S., Kita, M. M. and Marmor, M. F. (1992). Protection of rabbit retina from ischemic injury by superoxide dismutase and catalase. Invest. Ophthalmol. Vis. Sci. 33 (Suppl), 917.
22. Osborne, N. N., Block, F. and Sontag, K.-H. (1991). Reduction in ocular blood flow results in GFAP expression in rat retinal Müller cells. Vis. Neurosci. 7, 637-9.
23. Pelligrini-Giampietro, D. E., Cherici, G., Alesiani, M., Carla, V. and Moroni, F. (1990). Excitatory amino acid release and free radical formation may corporate in the genesis of ischemia-induced neuronal damage. J. Neurosci. 10, 1035-41.
24. Prehn, J. H. M., Karkoutly, C., Nuglisch, J., Peruche, B. and Krieglstein, J. (1992). Didydrolipoate reduces neuronal injury after cerebral ischemia. J. Cereb. Blood Flow Metab. 12, 78-87.
25. Sato, P. H. and Hall, E. D. (1992). Tirilazad protects vitamins C and E in brain ischemia-reperfusion injury. J. Neurochem. 58, 2263-8.
26. Siesjö, B. K. (1990). Calcium in the brain under physiological and pathologic conditions. Eur. Neurol. 30(suppl), 3-9.
27. Siesjö, B. K., Agardh, C.-D. and Bengtsson, F. (1989). Free radicals and brain damage. Cerebrovasc. Brain Metab. Rev. 1, 165-211.
28. Szabo, M. E., Droy-Lefaix, M. T., Doly, M. and Braquest, P. (1991). Free radical-mediated effects in reperfusion injury: a histological study with SOD and EGB761 in rat retina. Ophthalmic. Res. 23, 225-34.
29. Veriac, S., Tissie, G. and Bonne, C. (1993). Oxygen free radicals adversely affect the regulation of vascular tone by nitric oxide in the rabbit retina under high intraocular pressure. Exp. Eye Res. 56, 85-8.
30. Yoon, Y. H. and Marmor, M. F. (1989). Dextromethorphan protects retina against ischemic injury in vivo. Arch. Ophthalmol. 107, 409-11.
31. Zager, E. L. and Ames, A. (1988). Reduction of cellular energy requirements. Screening for agents that may protect against CNS ischemia. J. Neurosurg. 69, 568-79.