Microfluidic chip for biochemical reaction and electrophoretic separation by quantitative volume control

Sensors and Actuators, B: Chemical

Volumn 110, Issue 1, 2005, Pages 164-173

  Lee, Sang Ho ^a,b   Cho, Seung Il ^a   Lee, Chang Soo ^a   Kim, Byung Gee ^a   Kim, Yong Kweon ^a  

^a Seoul National University   (South Korea)

^b University of California   (United States)

Author keywords

Capillary pressure; Enzyme reaction; Microchip electrophoresis; Microfluidics; Pneumatic sample injection

Indexed keywords

CAPILLARITY; ELECTROPHORESIS; ENZYMES; FLUIDICS; HYDROSTATIC PRESSURE; MICROELECTRODES;

CAPILLARY PRESSURE; ENZYME REACTION; MICROCHIP ELECTROPHORESIS; MICROFLUIDICS; PNEUMATIC SAMPLE INJECTION;

MICROPROCESSOR CHIPS;

EID: 23144464867     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2005.01.030     Document Type: Article

References (33)

1. T. Vilkner, D. Janasek, and A. Manz Micro total analysis systems Recent developments Anal. Chem. 76 2004 3373 3386
2. G.J.M. Bruin Recent developments in electrokinetically driven analysis on microfabricated devices Electrophoresis 21 2000 3931 3951
3. S. Mouradian Lab-on-a-chip: applications in proteomics Curr. Opin. Biotechnol. 6 2001 51 56
4. M.A. Burns, B.N. Johnson, S.N. Brahmasandra, K. Handique, J.R. Webster, M. Krishnan, T.S. Sammarco, P.M. Man, D. Jones, D. Heldsinger, C.H. Mastrangelo, and D.T. Burke An integrated nanoliter DNA analysis device Science 282 1998 484 487
5. D.J. Harrison, K. Fluri, K. Seiler, B.Z. Fan, C.S. Effenhauser, and A. Manz Micromachining a miniaturized capillary electrophoresis-based chemical analysis system on a chip Science 261 1993 895 897
6. B.M. Paegel, C.A. Emrich, G.J. Wedmayer, J.R. Scherer, and R.A. Mathies High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor Proc. Natl. Acad. Sci. 99 2002 574 579
7. E.T. Lagally, C.A. Emrich, and R.A. Mathies Fully integrated PCR-capillary electrophoresis microsystem for DNA analysis Lab Chip 1 2001 102 107
8. D.J. Harrison, P.G. Glavina, and A. Manz Towards miniaturized electrophoresis and chemical analysis systems on silicon: an alternative to chemical sensors Sens. Actuators B: Chem. 10 1993 107 116
9. V. Dolnik, S. Liu, and S. Jovanovich Capillary electrophoresis on micro chip Electrophoresis 21 2000 41 54
10. J. Khandurina, T.E. McKnight, S.C. Jacobson, L.C. Waters, R.S. Foote, and J.M. Ramsey Integrated system for rapid PCR-based DNA analysis in microfluidic devices Anal. Chem. 72 2000 2995 3000
11. B.J. Burke, and F.E. Regnier Electrophoretically mediated microanalysis of β-galactosidase on microchips Electrophoresis 22 2001 3744 3751
12. S.C. Jacobson, R. Hergenröder, A.W. Moore Jr., and J.M. Ramsey Precolumn reactions with electrophoretic analysis integrated on a microchip Anal. Chem. 66 1994 4127 4132
13. S.C. Jacobson, C.T. Culbertson, J.E. Daler, and J.M. Ramsey Microchip structures for submillisecond electrophoresis Anal. Chem. 70 1998 3476 3480
14. S.C. Jacobson, R. Hergenröder, L.B. Koutny, R.J. Warmack, and J.M. Ramsey Effects of injection schemes and column geometry on the performance of microchip electrophoresis devices Anal. Chem. 66 1994 1107 1113
15. B.E. Slentz, N.A. Penner, and F. Regnier Sampling bias at channel junctions in gated flow injection on chips Anal. Chem. 74 2002 4835 4840
16. A.P. O'Neil, P. O'Brien, J. Alderman, D. Hoffman, M. McEnergy, J. Murrihy, and J.D. Glennon On-chip definition of picolitre sample injection plugs for miniaturised liquid chromatography J. Chromatogr. A 924 2001 259 263
17. M. Yamada, and M. Seki Nanoliter-sized liquid dispenser array for multiple biochemical analysis in microfluidic devices Anal. Chem. 76 2004 895 899
18. X. Bai, H.J. Lee, J.S. Rossier, F. Reymond, H. Schafer, M. Wossner, and H.H. Girault Pressure-pinched injection of nanolitre volumes in planar micro analytical devices Lab chip 2 2002 45 49
19. D. Solignac, and M.A.M. Gijs Pressure pulse injection: a powerful alternative to electrokinetic sample loading in electrophoresis microchips Anal. Chem. 75 2003 1652 1657
20. S. Kaneda, and T. Fujii Combining droplet-based liquid handling and on-chip capillary electrophoresis with new sample injection method Proceedings of the Micro Total Analysis Systems'03 Squaw Valley, CA, USA, October 5-9 2003
21. S.-H. Lee, C.-S. Lee, B.-G. Kim, and Y.-K. Kim Quantitatively controlled nanoliter liquid manipulation using hydrophobic valving and control of surface wettability J. Micromech. Microeng. 13 2003 89 97
22. S.I. Cho, K.-N. Lee, Y.-K. Kim, J. Jang, and D.S. Chung Chiral separation of gemifloxacin in sodium-containing media using chiral crown ether as a chiral selector by capillary and microchip electrophoresis Electrophoresis 23 2002 972 977
23. S.-H. Lee, C.-S. Lee, D.-S. Shin, B.-G. Kim, Y.-S. Lee, and Y.-K. Kim Micro protein patterning using a liftoff process with fluorocarbon thin film Sens. Actuators B: Chem. 99 2003 623 632
24. C.-S. Lee, S.-H. Lee, S.-S. Park, Y.-K. Kim, and B.-G. Kim Protein patterning on silicon-based surface using background hydrophobic thin film Biosens. Bioelectron. 18 2003 437 444
25. K. Hosokawa, T. Fujii, and I. Endo Handling of picoliter liquid samples in a poly(dimethylsiloxane)-based microfluidic device Anal. Chem. 71 1999 4781 4785
26. K. Handique, D.T. Burke, C.H. Mastrangelo, and M.A. Burns Nanoliter liquid metering in microchannels using hydrophobic patterns Anal. Chem. 72 2000 4100 4109
27. B. Zhao, J.S. Moore, and D.J. Beebe Surface-directed liquid flow inside microchannels Science 291 2001 1023 1026
28. S.-H. Lee, S.I. Cho, D.S. Chung, and Y.-K. Kim Microchip electrophoresis integrated with nanofluidic sample handling Proceedings of the Micro Total Analysis Systems'02 Nara, Japan, November 3-7 2002
29. J.W. Mihm, and G. Leob M.E. Schrader G.I. Loeb Modern Approaches to Wettability 1992 Plenum Press New York 263 326 (Chapter 10)
30. D.J. Shaw Introduction to Colloid and Surface Chemistry 4th ed. 1998 Butterworth-Heinemann Oxford p. 93
31. R.H. Liu, M.A. Stremler, K.V. Sharp, M.G. Olsen, J.G. Santiago, R.J. Adrian, H. Aref, and D.J. Beebe Passive mixing in a three-dimensional serpentine microchannel J. Microelectromech. Syst. 9 2000 190 197
32. S.-S. Park, S.I. Cho, M.-S. Kim, Y.-K. Kim, and B.-G. Kim Integration of on-column immobilized enzyme reactor in microchip electrophoresis Electrophoresis 24 2003 200 206
33. D.R. Baker Capillary Electrophoresis 1995 Wiley New York pp. 1-48