Viscoelastic evaluation of topical creams containing microcrystalline cellulose/sodium carboxymethyl cellulose as stabilizer

AAPS PharmSciTech

Volumn 3, Issue 2, 2002, Pages

  Adeyeye, Moji Christianah ^a   Jain, Ashwinkumar C ^a   Ghorab, Mohamed K M ^a   Reilly Jr , William J ^b  

^a DUQUESNE UNIVERSITY   (United States)

^b Independent Pharmaceutical Formulation Consultant   (United States)

Author keywords

Bridging flocculation; Cream Avicel CL 611; Hydrocortisone acetate; Loss modulus; Microstructure; Storage modulus; Thixotropic; Viscoelastic

Indexed keywords

AVICEL CL 611; CARBOXYMETHYLCELLULOSE; GLYCEROL STEARATE; HEXADECANOL; HYDROCORTISONE ACETATE; METHYL PARABEN; MICROCRYSTALLINE CELLULOSE; PROPYL PARABEN; PROPYLENE GLYCOL; STABILIZING AGENT; ANTIINFLAMMATORY AGENT; CELLULOSE; DRUG DERIVATIVE; HYDROCORTISONE; OINTMENT BASE;

ARTICLE; CONTINUOUS FLOW REACTOR; CONTROLLED STUDY; CORRELATION ANALYSIS; CREAM; DRUG FORMULATION; DRUG RELEASE; DRUG STORAGE; ELASTICITY; FLOW MEASUREMENT; GEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PREDICTION; SHEAR STRESS; STRESS; STRESS STRAIN RELATIONSHIP; THIXOTROPY; VISCOSITY; YOUNG MODULUS; CHEMISTRY; COMPARATIVE STUDY; FLOW KINETICS; INSTRUMENTATION; MECHANICAL STRESS; METABOLISM; METHODOLOGY; PHARMACEUTICS; RADIATION EXPOSURE; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANTI-INFLAMMATORY AGENTS; CARBOXYMETHYLCELLULOSE; CELLULOSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STORAGE; ELASTICITY; HYDROCORTISONE; OINTMENT BASES; RHEOLOGY; STRESS, MECHANICAL; TECHNOLOGY, PHARMACEUTICAL; VISCOSITY;

EID: 23144461095     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt030208     Document Type: Article

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