Synthesis and characterization of methacrylic derivatives of 5-amino salicylic acid with pH-sensitive swelling properties

AAPS PharmSciTech

Volumn 2, Issue 4, 2001, Pages 6-

  Davaran, S ^a   Rashidi, M R ^a   Hashemi, M ^a  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

5 ASA; Colon targeting; Hydrogel; Hydrolysis; Methacrylic copolymers

Indexed keywords

MACROGOL DERIVATIVE; MESALAZINE; NONSTEROID ANTIINFLAMMATORY AGENT; POLY (METHACRYLIC ACID CO ETHYLENEGLYCOL MONOMETHOACRYLATE CO METHACRYLOYLOXYETHYL 5 AMINO SALICYLATE); POLY (METHACRYLIC ACID-CO-ETHYLENEGLYCOL MONOMETHOACRYLATE-CO-METHACRYLOYLOXYETHYL 5-AMINO SALICYLATE); POLYMER; POLYMETHACRYLIC ACID DERIVATIVE; METHACRYLIC ACID DERIVATIVE; METHACRYLOYLOXYETHYL 5 AMINO SALICYLATE; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; CHEMISTRY; COLON; DELAYED RELEASE FORMULATION; HYDROGEL; PH; SYNTHESIS; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG HYDROLYSIS; DRUG RELEASE; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; INTESTINE FLUID; MATHEMATICAL COMPUTING; POLYMERIZATION; SIMULATION; STOMACH PH; TISSUE SPECIFICITY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; COLON; DELAYED-ACTION PREPARATIONS; HYDROGELS; HYDROGEN-ION CONCENTRATION; MESALAMINE; POLYETHYLENE GLYCOLS; POLYMERS; POLYMETHACRYLIC ACIDS;

EID: 23144440011     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1007/bf02830569     Document Type: Article

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