Characterization of tetraethylammonium uptake across the basolateral membrane of the Drosophila Malpighian (renal) tubule

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 289, Issue 2 58-2, 2005, Pages

  Rheault, Mark R ^a,b   Debicki, Donna M ^a   O'Donnell, Michael J ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Comparative renal physiology; Drosophila melanogaster; Malpighian tubule; Organic cation transport

Indexed keywords

CIMETIDINE; ORGANIC CATION TRANSPORTER; QUININE; TRIMETHYLAMMONIUM SALT DERIVATIVE; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BASOLATERAL MEMBRANE; CATION TRANSPORT; COMPETITIVE INHIBITION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; DRUG UPTAKE; HYPERPOLARIZATION; MALPIGHIAN TUBULE; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; METABOLIC REGULATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; SECOND MESSENGER;

EID: 23044499857     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00109.2005     Document Type: Article

References (40)

1. Armstrong CM and Binstock L. Anomalous rectification in squid giant axon injected with tetraethylammonium chloride. J Gen Physiol 48: 859-872, 1965.
2. Ashburner M. Drosophila: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
3. Boom SAP, Gribnau FWJ, and Russel FGM. Organic cation transport and cationic drug interactions in freshly isolated proximal tubular cells of the rat. J Pharmacol Exp Ther 263: 445-450, 1992.
4. Brändle E and Greven J. Transport of Cimetidine across the basolateral membrane of rabbit kidney proximal tubules: characterization of transport mechanisms. J Pharmacol Exp Ther 258: 1038-1045, 1991.
5. 1-methylnicotinamide transport by isolated perfused snake renal tubules. Am J Physiol Renal Fluid Electrolyte Physiol 250: F407-F418, 1986.
6. Dantzler WH, Evans KK, and Wright WH. Basolateral choline transport in isolated rabbit renal proximal tubules. Pflügers Arch 436: 899-905, 1998.
7. Dow JAT, Maddrell SHP, Görtz A, Skaer NJV, Brogan S, and Kaiser K. The Malpighian tubules of Drosophila melanogaster, a novel phenotype for studies of fluid secretion and its control. J Exp Biol 197: 421-428, 1994.
8. Dow JAT and Davies SA. The Drosophila melanogaster Malpighian tubule, a genetic model for insect epithelia. Adv Insect Physiol 28: 1-83, 2001.
9. Gaertner LS, Murray CL, and Morris CE. Transepithelial transport of nicotine and vinblastine in isolated Malpighian tubules of the tobacco hornworm (Manduca sexta) suggests a p-glycoprotein-like mechanism. J Exp Biol 201: 2637-2645, 1998.
10. Gekeler V, Ise W, Sanders KH, Ulrich WR, and Beck J. The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance. Biochem Biophys Res Commun 208: 345-352, 1995.
11. Groves CE, Evans KK, Dantzler WH, and Wright SH. Peritubular organic cation transport in isolated rabbit proximal tubules. Am J Physiol Renal Fluid Electrolyte Physiol 266: F450-F458, 1994.
12. Hazel MH, Ianowski JP, Christensen RJ, Maddrell SHP, and O'Donnell MJ. Amino acids modulate ion transport and fluid secretion by insect Malpighian tubules. J Exp Biol 206: 79-91, 2003.
13. Hille B. Potassium channels and chloride channels. In: Ionic Channels of Excitable Membranes. Sunderland, MA: Sinauer, 1992, p 131-162.
14. Hodgkin AL and Katz B. The effect of sodium ions on the electrical activity of the giant axon of the squid. J Physiol 108: 37-77, 1949.
15. - conductance. J Exp Biol 207: 2599-2609, 2004.
16. Kaewmokul S, Chatsudthipong V, Evans KK, Dantzler WH, and Wright SH. Functional mapping of rbOCT1 and rbOCT2 activity in the S2 segment of rabbit proximal tubule. Am J Physiol Renal Physiol 285: F1149-F1159, 2003.
17. Kim YK and Dantzler WH. Relation of membrane potential to basolateral TEA transport in isolated snake proximal tubules. Am J Physiol Regul Integr Comp Physiol 268: R1539-R1545, 1995.
18. 2+ effects on basolateral tetraethylammonium transport in isolated snake renal proximal tubules. Pflügers Arch 435: 28-33, 1997.
19. +-ATPase to basolateral ion transport in Malpighian tubules of Drosophila melanogaster. J Exp Biol 202: 1561-1570, 1999.
20. Linton SM and O'Donnell MJ. Novel aspects of the transport of organic anions by the Malpighian tubules of Drosophila melanogaster. J Exp Biol 203: 3575-3584, 2000.
21. Maddrell SH and Gardiner BOC. Excretion of alkaloids by Malpighian tubules of insects. J Exp Biol 64: 267-281, 1976.
22. Maddrell SH and O'Donnell MJ. Insect Malpighian tubules: V-ATPase action in ion and fluid transport. J Exp Biol 172: 417-479, 1992.
23. McKinney TD, Myers P, and Speef KV. Cimetidine secretion by rabbit renal tubules in vitro. Am J Physiol Renal Fluid Electrolyte Physiol 241: F69-F76, 1981.
24. Meijer DKF, Mol WE, Müller M, and Kurz G. Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations. J Pharmacokinet Biopharm 18: 35-70, 1990.
25. Miller DS and Holohan PD. Organic cation secretion in flounder renal tissue. Am J Physiol Regul Integr Comp Physiol 253: R861-R867, 1987.
26. Neame KD and Richards TG. Elementary Kinetics of Membrane Carrier Transport. New York: Wiley, 1972, p. 1-120.
27. Nijhout HF. Excretory role of the midgut in larvae of the tobacco hornworm, Manduca sexta (L.). J Exp Biol 62: 221-230, 1975.
28. O'Donnell MJ and Maddrell SH. Fluid reabsorption and ion transport by the lower Malpighian tubules of adult female Drosophila. J Exp Biol 198: 1643-1647, 1995.
29. O'Donnell MJ, Dow JAT, Huesmann GR, Tublitz NJ, and Maddrell SHP. Separate control of anion and cation transport in Malpighian tubules of Drosophila melanogaster. J Exp Biol 199: 1163-1175, 1996.
30. O'Donnell MJ and Spring JH. Modes of control of insect Malpighian tubules: synergism, antagonism, cooperation and autonomous regulation. J Insect Physiol 46: 107-117, 2000.
31. Pritchard JB and Miller DS. Mechanisms mediating renal secretion of organic anions and cations. Physiol Rev 73: 765-796, 1993.
32. Rheault MR and O'Donnell MJ. Organic cation transport by Malpighian tubules of Drosophila melanogaster: application of two novel electrophysiological techniques. J Exp Biol 207: 2173-2184, 2004.
33. Smith PM, Pritchard JB, Miller DS. Membrane potential drives organic cation transport in teleost renal proximal tubules. Am J Physiol Regul Integr Comp Physiol 255: R492-R499, 1988.
34. Taylor CA, Stanley KN, and Shirras AD. The Orel gene of Drosophila melanogaster codes for a putative organic cation transporter with six or 12 transmembrane domains. Gene 201: 69-74, 1997.
35. -, pH; inhibition by aliphatic primary, secondary, and tertiary amines, and mono and bisquaternary compounds. Pflügers Arch 419: 84-92, 1991.
36. Ullrich KJ, Rumrich G, Neiteler K, and Fritzsch G. Contraluminal transport of organic cations in the proximal tubule of the rate kidney. II. Specificity: anilines, phenylalkylamines (catecholamines), heterocyclic compounds (pyridines, quinolines, acridines). Pflügers Arch 420: 29-38, 1992.
37. Ullrich KJ, Rumrich G, David C, and Fritzsch G. Bisubstrates: substances that interact with renal Contraluminal organic anion and organic cation transport systems. I. Amines, piperidines, piperazines, azepines, pyridines, quinolines, imidazoles, thiazoles, guanidines, and hydrazines. Pflügers Arch 425: 280-299, 1992.
38. Wright SH, Evans KK, Zhang X, Cherrington NJ, Sitar DS, and Dantzler WH. Functional map of TEA transport activity in isolated rabbit renal proximal tubules. Am J Physiol Renal Physiol 287: F442-F451, 2004.
39. Wright SH and Dantzler WH. Molecular and cellular physiology of renal organic cation and anion transport. Physiol Rev 84: 987-1049, 2004.
40. Zhang X, Evans KK, and Wright SH. Molecular cloning of rabbit organic cation transporter rbOCT2 and functional comparisons with rbOCT1. Am J Physiol Renal Physiol 283: F124-F133, 2002.