Sexual dimorphism in urinary metabolite profiles of Han Wistar rats revealed by nuclear-magnetic-resonance-based metabonomics

Analytical Biochemistry

Volumn 343, Issue 2, 2005, Pages 195-202

  Stanley, E G ^a   Bailey, N J C ^b   Bollard, M E ^a   Haselden, J N ^c   Waterfield, C J ^c   Holmes, E ^a   Nicholson, J K ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Fyfield Business and Research Park   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Chemometrics; Chlorogenic acid metabolism; Gender variation; HPLC MS; Metabonomics; NMR spectroscopy

Indexed keywords

GENES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHASE SEPARATION; PHYSIOLOGICAL MODELS; PLANTS (BOTANY); RATS; SULFUR COMPOUNDS;

CHEMOMETRICS; CHLOROGENIC ACIDS; GENDER VARIATION; HPLC-MS; METABONOMICS;

METABOLITES;

3 HYDROXYPHENYLPROPIONIC ACID; ACETIC ACID DERIVATIVE; BIOLOGICAL MARKER; CHLOROGENIC ACID; CHOLIC ACID; GLYCINE DERIVATIVE; N ACETYLGLYCOPROTEIN; N,N' DIMETHYLGLYCINE; PROPIONIC ACID DERIVATIVE; SULFATE; TRIMETHYLAMINE OXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CHEMOMETRICS; CONCENTRATION (PARAMETERS); CONJUGATION; CONTROLLED STUDY; FEMALE; GENETIC VARIABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLISM; METABOLITE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SEX DIFFERENCE; SOLID PHASE EXTRACTION; STATISTICAL SIGNIFICANCE; URINALYSIS;

ANIMALIA; RATTUS NORVEGICUS;

EID: 23044483202     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2005.01.024     Document Type: Article

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