Plasma pharmacokinetics and faecal excretion of ivermectin (Eqvalan® paste) and doramectin (Dectomax®, 1%) following oral administration in donkeys

Research in Veterinary Science

Volumn 79, Issue 3, 2005, Pages 233-238

  Gokbulut, C ^a   Boyacioglu, M ^a   Karademir, U ^a  

^a ADNAN MENDERES UNIVERSITY   (Turkey)

Author keywords

Donkey; Doramectin; Environmental impact; Faecal excertion; Ivermectin; Pharmacokinetics

Indexed keywords

DORAMECTIN; IVERMECTIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DONKEY; DRUG BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG FECES LEVEL; DRUG HALF LIFE; DRY WEIGHT; MEAN RESIDENCE TIME; NONHUMAN; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ADMINISTRATION, ORAL; ANIMALS; ANTHELMINTICS; AREA UNDER CURVE; EQUIDAE; FECES; IVERMECTIN;

EQUUS ASINUS;

EID: 23044471852     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2005.01.002     Document Type: Article

References (19)

1. A.H. Atta M.N. Abo-Shihada Comparative pharmacokinetics of doramectin and ivermectin in sheep Journal of Veterinary Pharmacology and Therapeutics 23 2000 49-52
2. S. Barber V. Bowles A. Lespine M. Alvinerie The comparative serum disposition kinetics of subcutaneous administration of doramectin, ivermectin and moxidectin in the Australian Merino sheep Journal of Veterinary Pharmacology and Therapeutics 26 2003 343-348
3. S. Chiu M. Greene F.P. Baylis D. Eline A. Rosegay H. Meriwether T.A. Jacob Absorption, tissue distribution, and excretion of tritium-labeled ivermectin in cattle, sheep, and rat Journal of Agricultural and Food Chemistry 38 1990 2072-2078
4. C. Gokbulut A.M. Nolan Q.A. Mckellar Plasma pharmacokinetics and faecal excretion of ivermectin, doramectin and moxidectin after oral administration in horses Equine Veterinary Journal 33 2001 494-498
5. B.A. Halley W.J.A. Vandenheuvel P.G. Wislocki Environmental effects of the usage of avermectins in livestock Veterinary Parasitology 48 1993 109-125
6. C. Lanusse A. Lifschitz G. Virkel L. Alvarez S. Sanchez J.F. Sutra P. Galtier M. Alvinerie Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle. Journal of Veterinary Pharmacology and Therapeutics 20 1997 91-99
7. Lumaret, J.P., 1997. Ecological disturbance of endectocides on non-target fauna in pasture. In: Proceedings of the 16th International Conference of World Association for the Advancement of Veterinary Parasitology, Sun City, South Africa, p. 54
8. J.P Lumaret F. Errouissi Use of anthelmintics in herbivores and evaluation of risks for the non target fauna of pastures Veterinary Research 33 2002 547-562
9. S.E. Marriner I. McKinnon J.A. Bogan The pharmacokinetics of ivermectin after oral and subcutaneous administration to sheep and horses Journal of Veterinary Pharmacology and Therapeutics 10 1987 175-179
10. Q.A. Mckellar Ecotoxicology and residues of anthelmintic compounds Veterinary Parasitology 72 1997 413-426
11. Q.A. Mckellar H.A. Benchaoui Avermectins and milbemycins Journal of Veterinary Pharmacology and Therapeutics 19 1996 331-351
12. R. Perez I. Cabezas M. Garcia L. Rubilar J.F. Sutra P. Galtier M. Alvinerie Comparison of the pharmacokinetics of moxidectin (Equest®) and ivermectin (Eqvalan®) in horses Journal of Veterinary Pharmacology and Therapeutics 22 1999 174-180
13. R. Perez I. Cabezas J.F. Sutra P. Galtier M. Alvinerie Faecal excretion profile of moxidectin and ivermectin after oral administration in horses The Veterinary Journal 161 2001 85-92
14. R. Perez C. Godoy C. Palma I. Cabezas L. Munoz L. Rubilar M. Arboix M. Alvinerie Plasma profiles of ivermectin in horses following oral or intramuscular administration Journal of Veterinary Medicine A 50 2003 297-302
15. Scott, E.W., 1997. Pharmacokinetics of ivermectin in donkeys and ponies. In: Scott, E. (Ed.), Association for Veterinary Clinical Pharmacology and Therapeutics Proceedings, No. 15, Edinburgh, UK, pp. 20-21
16. W.L. Shoop B.F. Micheal H.W. Haines T.P. Murphy T.P. Faidley R. Hajdu D.R. Thompson Moxidectin and ivermectin in lambs: Plasma depletion and efficacy against helminths Journal of Veterinary Pharmacology and Therapeutics 20 1997 10-19
17. L. Strong S. James Some effects of ivermectin on the yellow dung fly, Scatophaga stercoraria Veterinary Parasitology 48 1993 181-191
18. L. Strong R. Wall Effects of ivermectin and moxidectin on the insects of cattle dung Bulletin of Entomological Research 84 1994 403-409
19. P.L. Toutain D.W. Upson T.N. Terhune M.E. Mckenzie Comparative pharmacokinetics of doramectin and ivermectin in cattle Veterinary Parasitology 72 1997 3-8