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Volumn 65, Issue 15, 2005, Pages 7013-7022

Cocarcinogenic effects of islet hormones and N-nitrosomorpholine in hepatocarcinogenesis after intrahepatic transplantation of pancreatic islets in streptozotocin-diabetic rats

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; NITROSOMORPHOLINE; PANCREAS HORMONE; POLYSTYRENE;

EID: 23044470044     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-0122     Document Type: Article
Times cited : (10)

References (34)
  • 1
    • 0002550061 scopus 로고
    • The cytoplasm of hepatocytes during carcinogenesis. Electron- and lightmicroscopical investigations of the nitrosomorpholine-intoxicated rat liver
    • Rentchnick P, editor. Berlin-Heidelberg: Springer
    • Bannasch P. The cytoplasm of hepatocytes during carcinogenesis. Electron- and lightmicroscopical investigations of the nitrosomorpholine-intoxicated rat liver. In: Rentchnick P, editor. Recent results in cancer research (Volume 19). Berlin-Heidelberg: Springer: 1968. p. 1-100.
    • (1968) Recent Results in Cancer Research , vol.19 , pp. 1-100
    • Bannasch, P.1
  • 2
    • 0031798943 scopus 로고    scopus 로고
    • Differential expression of key enzymes of energy metabolism in preneoplastic and neoplastic rat liver lesions induced by N-nitrosomorpholine and dehydroepiandrosterone
    • Mayer D, Metzger C, Leonetti P, Beier K, Benner A, Bannasch P. Differential expression of key enzymes of energy metabolism in preneoplastic and neoplastic rat liver lesions induced by N-nitrosomorpholine and dehydroepiandrosterone. Int J Cancer 1998;79:232-40.
    • (1998) Int J Cancer , vol.79 , pp. 232-240
    • Mayer, D.1    Metzger, C.2    Leonetti, P.3    Beier, K.4    Benner, A.5    Bannasch, P.6
  • 3
    • 0032405807 scopus 로고    scopus 로고
    • Xenomorphic hepatocellular precursors and neoplastic progression of tigroid cell foci induced in rats with low doses of N-nitrosomorpholine
    • Ströbel P, Klimek F, Zerban H, Kopp-Schneider A, Bannasch P. Xenomorphic hepatocellular precursors and neoplastic progression of tigroid cell foci induced in rats with low doses of N-nitrosomorpholine. Carcinogenesis 1998;19:2069-80.
    • (1998) Carcinogenesis , vol.19 , pp. 2069-2080
    • Ströbel, P.1    Klimek, F.2    Zerban, H.3    Kopp-Schneider, A.4    Bannasch, P.5
  • 4
    • 0028303879 scopus 로고
    • Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by single oral exposures to N-nitrosomorpholine
    • Weber E, Bannasch P. Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by single oral exposures to N-nitrosomorpholine. Carcinogenesis 1994;15:1219-26.
    • (1994) Carcinogenesis , vol.15 , pp. 1219-1226
    • Weber, E.1    Bannasch, P.2
  • 5
    • 0028334636 scopus 로고
    • Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced in stop experiment by oral exposure to N-nitrosomorpholine
    • Weber E, Bannasch P. Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced in stop experiment by oral exposure to N-nitrosomorpholine. Carcinogenesis 1994;15:1227-34.
    • (1994) Carcinogenesis , vol.15 , pp. 1227-1234
    • Weber, E.1    Bannasch, P.2
  • 6
    • 0028303881 scopus 로고
    • Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by continuous oral exposure to N-nitrosomorpholin
    • Weber E, Bannasch P. Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by continuous oral exposure to N-nitrosomorpholin. Carcinogenesis 1994;15:1235-42.
    • (1994) Carcinogenesis , vol.15 , pp. 1235-1242
    • Weber, E.1    Bannasch, P.2
  • 7
    • 0020361679 scopus 로고
    • Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver
    • Hacker HJ, Moore MA, Mayer D, Bannasch P. Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver. Carcinogenesis 1982;3:1265-72.
    • (1982) Carcinogenesis , vol.3 , pp. 1265-1272
    • Hacker, H.J.1    Moore, M.A.2    Mayer, D.3    Bannasch, P.4
  • 8
    • 0032521192 scopus 로고    scopus 로고
    • Cytochemical and biochemical studies on adenylate cyclase activity in preneoplastic and neoplastic liver tissue and cultured liver cells
    • Mayer D, Klimek F, Bannasch P. Cytochemical and biochemical studies on adenylate cyclase activity in preneoplastic and neoplastic liver tissue and cultured liver cells. Microsc Res Tech 1998;40:463-72.
    • (1998) Microsc Res Tech , vol.40 , pp. 463-472
    • Mayer, D.1    Klimek, F.2    Bannasch, P.3
  • 9
    • 0024399313 scopus 로고
    • Biochemical microanalysis of α-glucosidase activity in preneoplastic and neoplastic hepatic lesions induced in rats by N-nitrosomorpholine
    • Klimek F, Bannasch P. Biochemical microanalysis of α-glucosidase activity in preneoplastic and neoplastic hepatic lesions induced in rats by N-nitrosomorpholine. Virchows Arch B Cell Pathol Incl Mol Pathol 1989;57: 245-50.
    • (1989) Virchows Arch B Cell Pathol Incl Mol Pathol , vol.57 , pp. 245-250
    • Klimek, F.1    Bannasch, P.2
  • 10
    • 0022964468 scopus 로고
    • Loss of adenylate cyclase activity in preneoplastic and neoplastic lesions induced in rat liver by N-nitrosomorpholine
    • Ehemann V, Mayer D, Hacker HJ, Bannasch P. Loss of adenylate cyclase activity in preneoplastic and neoplastic lesions induced in rat liver by N-nitrosomorpholine. Carcinogenesis 1986;7:567-73.
    • (1986) Carcinogenesis , vol.7 , pp. 567-573
    • Ehemann, V.1    Mayer, D.2    Hacker, H.J.3    Bannasch, P.4
  • 11
    • 0021341353 scopus 로고
    • Biochemical microanalysis of glycogen content and glucose-6-phosphate dehydrogenase activity in focal lesions of the rat liver induced by N-nitrosomorpholin
    • Klimek F, Mayer D, Bannasch P. Biochemical microanalysis of glycogen content and glucose-6-phosphate dehydrogenase activity in focal lesions of the rat liver induced by N-nitrosomorpholin. Carcinogenesis 1984;5:265-8.
    • (1984) Carcinogenesis , vol.5 , pp. 265-268
    • Klimek, F.1    Mayer, D.2    Bannasch, P.3
  • 12
    • 0020365210 scopus 로고
    • The dose dependence and sequential appearance of putative preneoplastic populations induced in the rat liver by stop experiments with N-nitrosomorpholine
    • Moore MA, Mayer D, Bannasch P. The dose dependence and sequential appearance of putative preneoplastic populations induced in the rat liver by stop experiments with N-nitrosomorpholine. Carcinogenesis 1982;3:1429-36.
    • (1982) Carcinogenesis , vol.3 , pp. 1429-1436
    • Moore, M.A.1    Mayer, D.2    Bannasch, P.3
  • 13
    • 0035235718 scopus 로고    scopus 로고
    • Significance of hepatic preneoplasia for cancer chemoprevention
    • Miller AB, Bartsch H, Bofetta P, Dragsted L, Vainio H, editors. IARC Sci Publ. Lyon: IARC Press
    • Bannasch P, Nehrbass D, Kopp-Schneider A. Significance of hepatic preneoplasia for cancer chemoprevention. In: Miller AB, Bartsch H, Bofetta P, Dragsted L, Vainio H, editors. Biomarkers in cancer chemoprevention, no. 154, IARC Sci Publ. Lyon: IARC Press; 2001. p. 223-40.
    • (2001) Biomarkers in Cancer Chemoprevention , Issue.154 , pp. 223-240
    • Bannasch, P.1    Nehrbass, D.2    Kopp-Schneider, A.3
  • 14
    • 0030691794 scopus 로고    scopus 로고
    • Early bioenergetic changes in hepatocarcinogenesis: Preneoplastic phenotypes mimic responses to insulin and thyroid hormone
    • Bannasch P, Klimek F, Mayer D. Early bioenergetic changes in hepatocarcinogenesis: preneoplastic phenotypes mimic responses to insulin and thyroid hormone. J Bioenerg Biomembr 1997;29:303-13.
    • (1997) J Bioenerg Biomembr , vol.29 , pp. 303-313
    • Bannasch, P.1    Klimek, F.2    Mayer, D.3
  • 15
    • 0028149499 scopus 로고
    • Hyperproliferative liver acini after intraportal islet transplantation in streptozotocin-induced diabetic rats
    • Dombrowski F, Lehringer-Polzin M, Pfeifer U. Hyperproliferative liver acini after intraportal islet transplantation in streptozotocin-induced diabetic rats. Lab Invest 1994;71:688-99.
    • (1994) Lab Invest , vol.71 , pp. 688-699
    • Dombrowski, F.1    Lehringer-Polzin, M.2    Pfeifer, U.3
  • 16
    • 0029922052 scopus 로고    scopus 로고
    • Altered liver acini induced in diabetic rats by portal vein islet isografts resemble preneoplastic hepatic foci in their enzymic pattern
    • Dombrowski F, Filsinger E, Bannasch P, Pfeifer U. Altered liver acini induced in diabetic rats by portal vein islet isografts resemble preneoplastic hepatic foci in their enzymic pattern. Am J Pathol 1996;148:1249-56.
    • (1996) Am J Pathol , vol.148 , pp. 1249-1256
    • Dombrowski, F.1    Filsinger, E.2    Bannasch, P.3    Pfeifer, U.4
  • 17
    • 0031050882 scopus 로고    scopus 로고
    • Hepatocellular neoplasms induced by low-number pancreatic islet transplants in streptozotocin diabetic rats
    • Dombrowski F, Bannasch P, Pfeifer U. Hepatocellular neoplasms induced by low-number pancreatic islet transplants in streptozotocin diabetic rats. Am J Pathol 1997;150:1071-87.
    • (1997) Am J Pathol , vol.150 , pp. 1071-1087
    • Dombrowski, F.1    Bannasch, P.2    Pfeifer, U.3
  • 18
    • 0033828897 scopus 로고    scopus 로고
    • Analysis of the IGF axis in preneoplastic hepatic foci and hepatocellular neoplasms developing after low-number pancreatic islet transplantation into the livers of streptozotocin diabetic rats
    • Scharf JG, Ramadori G, Dombrowski F. Analysis of the IGF axis in preneoplastic hepatic foci and hepatocellular neoplasms developing after low-number pancreatic islet transplantation into the livers of streptozotocin diabetic rats. Lab Invest 2000;80: 1399-411.
    • (2000) Lab Invest , vol.80 , pp. 1399-1411
    • Scharf, J.G.1    Ramadori, G.2    Dombrowski, F.3
  • 19
    • 12344261004 scopus 로고    scopus 로고
    • Over-expression of fatty acid synthase in chemically and hormonally induced hepatocarcinogenesis of the rat
    • Evert M, Schneider-Stock R, Dombrowski F. Over-expression of fatty acid synthase in chemically and hormonally induced hepatocarcinogenesis of the rat. Lab Invest 2005;85:99-108.
    • (2005) Lab Invest , vol.85 , pp. 99-108
    • Evert, M.1    Schneider-Stock, R.2    Dombrowski, F.3
  • 20
    • 0034002793 scopus 로고    scopus 로고
    • Fatty-acid synthase and human cancer: New perspectives on its role in tumor biology
    • Kuhajda F. Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology. Nutrition 2000;16:202-8.
    • (2000) Nutrition , vol.16 , pp. 202-208
    • Kuhajda, F.1
  • 21
    • 7444249697 scopus 로고    scopus 로고
    • Insulin receptor, insulin receptor substrate-1, Raf-1, and Mek-1 during hormonal hepatocarcinogenesis by intrahepatic pancreatic islet transplantation in diabetic rats
    • Evert M, Sun JP, Pichler S, Slavova N, Schneider-Stock R, Dombrowski F. Insulin receptor, insulin receptor substrate-1, Raf-1. and Mek-1 during hormonal hepatocarcinogenesis by intrahepatic pancreatic islet transplantation in diabetic rats. Cancer Res 2004;64:8093-100.
    • (2004) Cancer Res , vol.64 , pp. 8093-8100
    • Evert, M.1    Sun, J.P.2    Pichler, S.3    Slavova, N.4    Schneider-Stock, R.5    Dombrowski, F.6
  • 22
    • 0014462639 scopus 로고
    • Stereological principles for morphometry in electron microscopic cytology
    • Weibel ER. Stereological principles for morphometry in electron microscopic cytology. Int Rev Cytol 1969;26:235-302.
    • (1969) Int Rev Cytol , vol.26 , pp. 235-302
    • Weibel, E.R.1
  • 23
    • 0043065488 scopus 로고    scopus 로고
    • Apolipoprotein A-IV mRNA overexpression in early preneoplastic hepatic foci induced by low-number pancreatic islet transplants in streptozotocin- diabetic rats
    • Evert M, Schneider-Stock R, Dombrowski F. Apolipoprotein A-IV mRNA overexpression in early preneoplastic hepatic foci induced by low-number pancreatic islet transplants in streptozotocin-diabetic rats. Pathol Res Pract 2003;199:373-9.
    • (2003) Pathol Res Pract , vol.199 , pp. 373-379
    • Evert, M.1    Schneider-Stock, R.2    Dombrowski, F.3
  • 24
    • 2642702617 scopus 로고    scopus 로고
    • Insulinomas derived from hyperplastic intra-hepatic islet transplants
    • Dombrowski F, Klingmüller D, Pfeifer U. Insulinomas derived from hyperplastic intra-hepatic islet transplants. Am J Pathol 1998;152:1025-38.
    • (1998) Am J Pathol , vol.152 , pp. 1025-1038
    • Dombrowski, F.1    Klingmüller, D.2    Pfeifer, U.3
  • 25
    • 0031883172 scopus 로고    scopus 로고
    • Overexpression of insulin receptor substrate-1 emerges early in hepatocarcinogenesis and elicits preneoplastic hepatic glycogenosis
    • Nehrbass D, Klimek F, Bannasch P. Overexpression of insulin receptor substrate-1 emerges early in hepatocarcinogenesis and elicits preneoplastic hepatic glycogenosis. Am J Pathol 1998;152:341-5.
    • (1998) Am J Pathol , vol.152 , pp. 341-345
    • Nehrbass, D.1    Klimek, F.2    Bannasch, P.3
  • 26
    • 0032971785 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 is over-expressed in glycogenotic but not in amphophilic preneoplastic hepatic foci induced in rats by N-nitrosomorpholine and dehydroepiandrosterone
    • Nehrbass D, Klimek F, Bannasch P, Mayer D. Insulin receptor substrate-1 is over-expressed in glycogenotic but not in amphophilic preneoplastic hepatic foci induced in rats by N-nitrosomorpholine and dehydroepiandrosterone. Cancer Lett 1999;140:75-9.
    • (1999) Cancer Lett , vol.140 , pp. 75-79
    • Nehrbass, D.1    Klimek, F.2    Bannasch, P.3    Mayer, D.4
  • 27
    • 0037255302 scopus 로고    scopus 로고
    • Significance of hepatic preneoplasia in risk identification and early detection of neoplasia
    • Bannasch P, Haertel T, Su Q. Significance of hepatic preneoplasia in risk identification and early detection of neoplasia. Toxicol Pathol 2003;31:134-9.
    • (2003) Toxicol Pathol , vol.31 , pp. 134-139
    • Bannasch, P.1    Haertel, T.2    Su, Q.3
  • 28
    • 0018189942 scopus 로고
    • Tumorigenic action of streptozotocin on the pancreas and kidney in male Wistar rats
    • Kazumi T, Yoshino G, Fujii S, Baba S. Tumorigenic action of streptozotocin on the pancreas and kidney in male Wistar rats. Cancer Res 1978;38:2144-7.
    • (1978) Cancer Res , vol.38 , pp. 2144-2147
    • Kazumi, T.1    Yoshino, G.2    Fujii, S.3    Baba, S.4
  • 29
    • 9644294263 scopus 로고    scopus 로고
    • Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus
    • Rother KI, Harlan DM. Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus. J Clin Invest 2004;114:877-83.
    • (2004) J Clin Invest , vol.114 , pp. 877-883
    • Rother, K.I.1    Harlan, D.M.2
  • 30
    • 1842731851 scopus 로고    scopus 로고
    • Clinical islet transplantation: Advances and immunological challenges
    • Ricordi C, Strom TB. Clinical islet transplantation: advances and immunological challenges. Nat Rev Immunol 2004;4:259-68.
    • (2004) Nat Rev Immunol , vol.4 , pp. 259-268
    • Ricordi, C.1    Strom, T.B.2
  • 31
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000;343:230-8.
    • (2000) N Engl J Med , vol.343 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3
  • 32
    • 9444291835 scopus 로고    scopus 로고
    • Islet graft assessment in the Edmonton protocol: Implications for predicting long-term clinical outcome
    • Street CN, Lakey JR, Shapiro AM, et al. Islet graft assessment in the Edmonton protocol: implications for predicting long-term clinical outcome. Diabetes 2004;53:3107-14.
    • (2004) Diabetes , vol.53 , pp. 3107-3114
    • Street, C.N.1    Lakey, J.R.2    Shapiro, A.M.3
  • 33
    • 0036925183 scopus 로고    scopus 로고
    • Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using Edmonton protocol immunosuppression
    • Hirshberg B, Mog S, Patterson N, Leconte J, Harlan DM. Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using Edmonton protocol immunosuppression. J Clin Endocrinol Metab 2002;87:5424-9.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5424-5429
    • Hirshberg, B.1    Mog, S.2    Patterson, N.3    Leconte, J.4    Harlan, D.M.5
  • 34
    • 0037261429 scopus 로고    scopus 로고
    • Relevance of hepatic preneoplasia for human hepatocarcinogenesis
    • Su Q, Bannasch P. Relevance of hepatic preneoplasia for human hepatocarcinogenesis. Toxicol Pathol 2003;31:126-33.
    • (2003) Toxicol Pathol , vol.31 , pp. 126-133
    • Su, Q.1    Bannasch, P.2


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