Tetracycline at subcytotoxic levels inhibits matrix metalloproteinase-2 and -9 but does not remove the smear layer

Journal of Periodontology

Volumn 76, Issue 7, 2005, Pages 1129-1139

  Wang, Yao ^a   Morlandt, Anthony B ^a   Xu, Xiaoping ^a   Carnes Jr , David L ^a   Chen, Zhihua ^a   Steffensen, Bjorn ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Cytotoxicity; Metalloproteinases, matrix; Periodontal diseases drug therapy; Periodontal regeneration; Smear layer; Tetracycline therapeutic use; Tooth root

Indexed keywords

GELATINASE A; GELATINASE B; TETRACYCLINE;

ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DENTAL SURGERY; DRUG DOSE REGIMEN; DRUG EFFICACY; ENZYME ASSAY; ENZYME INHIBITION; GINGIVA; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; PERIODONTAL LIGAMENT; SCANNING ELECTRON MICROSCOPY; STATISTICAL ANALYSIS;

ANTI-BACTERIAL AGENTS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GINGIVA; HUMANS; INHIBITORY CONCENTRATION 50; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; PERIODONTAL LIGAMENT; PROTEASE INHIBITORS; SMEAR LAYER; TETRACYCLINE; TOOTH ROOT;

EID: 23044442613     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2005.76.7.1129     Document Type: Article

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