Effects of estrogens and the phytoestrogen genistein on adipogenesis and lipogenesis in males and females

Birth Defects Research Part A - Clinical and Molecular Teratology

Volumn 73, Issue 7, 2005, Pages 472-473

  Cooke, Paul S ^a   Naaz, Afia ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; DAIDZEIN; ESTRADIOL; ESTROGEN DERIVATIVE; ESTROGEN RECEPTOR ALPHA; GENISTEIN; LIPOPROTEIN LIPASE; PHYTOESTROGEN; PROTEIN P21; PROTEIN P27;

ADIPOCYTE; ANIMAL CELL; BODY FAT; CELL COUNT; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL HYPERPLASIA; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CONFERENCE PAPER; ENZYME INHIBITION; FEMALE; INSULIN RESISTANCE; LIPOGENESIS; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN TARGETING; REGULATORY MECHANISM;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; GENISTEIN; HUMANS; LIPID METABOLISM; MALE; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; PHYTOESTROGENS;

ANIMALIA;

EID: 22944462662     PISSN: 15420752     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdra.20142     Document Type: Conference Paper

References (6)

1. Dang ZC, Audinot V, Papapoulos SE, et al. 2003. Peroxisome proliferator-activated receptor gamma (PPARgamma) as a molecular target for the soy phytoestrogen genistein. J Biol Chem 278:962-967.
2. Heine PA, Taylor JA, Iwamoto GA, et al. 2000. Increased adipose tissue in male and female estrogen receptor-alpha knockout mice. Proc Natl Acad Sci USA 97:12729-12734.
3. Jones ME, Thorburn AW, Britt KL, et al. 2000. Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity. Proc Natl Acad Sci USA 97:12735-12740.
4. Maffei L, Murata Y, Rochira V, et al. 2004. Dysmetabolic syndrome in a man with a novel mutation of the aromatase gene: effects of testosterone, alendronate, and estradiol treatment. J Clin Endocrinol Metab 89:61-70.
5. Naaz A, Yellayi S, Zakroczymski MA, et al. 2003. The soy isoflavone genistein decreases adipose deposition in mice. Endocrinology 144: 3315-3320.
6. Naaz A, Holsberger DR, Iwamoto GA, et al. 2004. Loss of cyclin-dependent kinase inhibitors produces adipocyte hyperplasia and obesity. FASEB J 18:1925-1927.